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Cellular Oncology

Issue 5/2022

Content (17 Articles)

Cholesterol homeostasis and cancer: a new perspective on the low-density lipoprotein receptor

Jia Gu, Neng Zhu, Hong-Fang Li, Tan-Jun Zhao, Chan-Juan Zhang, Duan-Fang Liao, Li Qin

A comprehensive review of SHP2 and its role in cancer

Moges Dessale Asmamaw, Xiao-Jing Shi, Li-Rong Zhang, Hong-Min Liu

Review

HDAC6: A unique HDAC family member as a cancer target

Sumeet Kaur, Prerna Rajoria, Madhu Chopra

Metastasis Original Article

Therapeutic exosomes loaded with SERPINA5 attenuated endometrial cancer cell migration via the integrin β1/FAK signaling pathway

Yunfeng Song, Lei Ye, Yuan Tan, Huan Tong, Zeheng Lv, Xiaoping Wan, Yiran Li

Breast Cancer Original Article

Direct knockdown of phospho-PTM targets mediated by TRIM21 can improve personalized treatment in breast cancer

Pranay Dey, Mansi Joshi, Aaiyas Mujawar, Renu Malhotra, Abhijit De

Open Access Esophageal Cancer Original Article

YAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma

Yi-Zih Kuo, Ya-Rong Kang, Wei-Lun Chang, Lydia Chin-Ling Sim, Tzu-Chin Hsieh, Chu-Han Chang, Yi-Ching Wang, Ching-Jung Tsai, Li-Chun Huang, Sen-Tien Tsai, Li-Wha Wu

Open Access Correction

Correction to: YAP1 acts as a negative regulator of pro-tumor TAZ expression in esophageal squamous cell carcinoma

Yi-Zih Kuo, Ya-Rong Kang, Wei-Lun Chang, Lydia Chin Ling Sim, Tzu-Chin Hsieh, Chu-Han Chang, Yi-Ching Wang, Ching-Jung Tsai, Li-Chun Huang, Sen-Tien Tsai, Li-Wha Wu

Open Access NSCLC Original Article

Activation of the HSP27-AKT axis contributes to gefitinib resistance in non-small cell lung cancer cells independent of EGFR mutations

Seul-Ki Choi, Minsuh Kim, Haeseung Lee, Youngjoo Kwon, Hyuk-Jin Cha, Se Jin Jang, Younghwa Na, Yun-Sil Lee

NSCLC Original Article

Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer

Shanshan Wang, Taishu Wang, Qianyi Yang, Shaoxuan Cheng, Fang Liu, Guoheng Yang, Fuqiang Wang, Ruilin Wang, Dian Yang, Mingyu Zhou, Chengen Duan, Yingqiu Zhang, Han Liu, Zhaoxia Dai, Kang Tian, Shuyan Liu

Herpes Virus Original Article

Nm23-H1 induces apoptosis in primary effusion lymphoma cells via inhibition of NF-κB signaling through interaction with oncogenic latent protein vFLIP K13 of Kaposi’s sarcoma-associated herpes virus

Suchitra Mohanty, Amit Kumar, Piyanki Das, Sushil Kumar Sahu, Ratnadeep Mukherjee, Rajagopal Ramachandranpillai, Santhosh Sankaran Nair, Tathagata Choudhuri

Open Access Neuroblastoma Original Article

Telomerase-targeting compounds Imetelstat and 6-thio-dG act synergistically with chemotherapy in high-risk neuroblastoma models

Janina Fischer-Mertens, Felix Otte, Andrea Roderwieser, Carolina Rosswog, Yvonne Kahlert, Lisa Werr, Anna-Maria Hellmann, Maya Berding, Bill Chiu, Christoph Bartenhagen, Matthias Fischer

Acute Myeloid Leukemia Original Article

Combination of RSK inhibitor LJH-685 and FLT3 inhibitor FF-10101 promoted apoptosis and proliferation inhibition of AML cell lines

Sen Zhang, Jun Liu, Zi-Yi Lu, Yu-Tong Xue, Xing-Ru Mu, Yang Liu, Jiang Cao, Zhen-Yu Li, Feng Li, Kai-Lin Xu, Qing-Yun Wu

Heterogeneity, inherent and acquired drug resistance in patient-derived organoid models of primary liver cancer

Linfeng Xian, Pei Zhao, Xi Chen, Zhimin Wei, Hongxiang Ji, Jun Zhao, Wenbin Liu, Zishuai Li, Donghong Liu, Xue Han, Youwen Qian, Hui Dong, Xiong Zhou, Junyan Fan, Xiaoqiong Zhu, Jianhua Yin, Xiaojie Tan, Dongming Jiang, Hongping Yu, Guangwen Cao

Correction to: CCL18 secreted from M2 macrophages promotes migration and invasion via the PI3K/Akt pathway in gallbladder cancer

Zhenyu Zhou, Yaorong Peng, Xiaoying Wu, Shiyu Meng, Wei Yu, Jinghua Zhao, Heyun Zhang, Jie Wang, Wenbin Li

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine