Issue 10/2020
Content (21 Articles)
Are we ready to use TMB in breast cancer clinical practice?
Sara Ravaioli, Francesco Limarzi, Maria Maddalena Tumedei, Michela Palleschi, Roberta Maltoni, Sara Bravaccini
Economic evaluations of cancer immunotherapy: a systematic review and quality evaluation
Charlotte Couchoud, Philippe Fagnoni, François Aubin, Virginie Westeel, Tristan Maurina, Antoine Thiery-Vuillemin, Claire Gerard, Marie Kroemer, Christophe Borg, Samuel Limat, Virginie Nerich
Therapeutic ISCOMATRIX™ adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer
Adele M. Barr, Anabel Silva, Sandro Prato, Gabrielle T. Belz, Eugene Maraskovsky, Adriana Baz Morelli
Activated HIF1α of tumor cells promotes chemoresistance development via recruiting GDF15-producing tumor-associated macrophages in gastric cancer
Shan Yu, Qian Li, Yiyi Yu, Yuehong Cui, Wei Li, Tianshu Liu, Fenglin Liu
Expression of immune checkpoints and T cell exhaustion markers in early and advanced stages of colorectal cancer
Reem Saleh, Rowaida Z. Taha, Salman M. Toor, Varun Sasidharan Nair, Khaled Murshed, Mahwish Khawar, Mahmood Al-Dhaheri, Mahir Abdulla Petkar, Mohamed Abu Nada, Eyad Elkord
Integrity of plasma DNA is inversely correlated with vaccine-induced antitumor immunity in ovarian cancer patients
Kayoko Waki, Kanako Yokomizo, Kouichiro Kawano, Naotake Tsuda, Nobukazu Komatsu, Akira Yamada
The effects of tumor resection and adjuvant therapy on the peripheral blood immune cell profile in patients with colon carcinoma
Daniëlle Krijgsman, Natasja L. De Vries, Morten N. Andersen, Anni Skovbo, Rob A. E. M. Tollenaar, Esther Bastiaannet, Peter J. K. Kuppen, Marianne Hokland
Prevention of liver metastases through perioperative acute CpG-C immune stimulation
Liat Sorski, Rivka Melamed, Ben Levi, Pini Matzner, Hagar Lavon, Ella Rosenne, Lee Shaashua, Itay Ricon, Elad Sandbank, Amit Benbenishty, Shamgar Ben-Eliyahu
Successful treatment of steroid-refractory immune checkpoint inhibitor-related pneumonitis with triple combination therapy: a case report
Hirofumi Utsumi, Jun Araya, Keitaro Okuda, Junko Watanabe, Daisuke Takekoshi, Yu Fujita, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takanori Numata, Hiromichi Hara, Kazuyoshi Kuwano
Galectin-9 expression as a poor prognostic factor in patients with renal cell carcinoma
Ryosuke Jikuya, Takeshi Kishida, Masahiko Sakaguchi, Tomoyuki Yokose, Masato Yasui, Akihito Hashizume, Tomoyuki Tatenuma, Nobuhiko Mizuno, Kentaro Muraoka, Susumu Umemoto, Masaki Kawai, Mitsuyo Yoshihara, Yoshiyasu Nakamura, Yohei Miyagi, Tetsuro Sasada
Expression of programmed death-ligand 1 (PD-L1) in human pituitary neuroendocrine tumor
Valentine Suteau, Alexandre Collin, Philippe Menei, Patrice Rodien, Marie-Christine Rousselet, Claire Briet
Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion
Ellyn Hughes, Sarah N. Lauder, Kathryn Smart, Anja Bloom, Jake Scott, Emma Jones, Michelle Somerville, Molly Browne, Andrew Blainey, Andrew Godkin, Ann Ager, Awen Gallimore
Immune checkpoint inhibitors reverse tolerogenic mechanisms induced by melanoma targeted radionuclide therapy
Jacques Rouanet, Valentin Benboubker, Hussein Akil, Ana Hennino, Philippe Auzeloux, Sophie Besse, Bruno Pereira, Solène Delorme, Sandrine Mansard, Michel D’Incan, Françoise Degoul, Paul-Olivier Rouzaire
PD-L1 expression correlates with tumor-infiltrating lymphocytes and better prognosis in patients with HPV-negative head and neck squamous cell carcinomas
Mario Sanchez-Canteli, Rocio Granda-Díaz, Nagore del Rio-Ibisate, Eva Allonca, Fernando López-Alvarez, Jackeline Agorreta, Irati Garmendia, Luis M. Montuenga, Juana M. García-Pedrero, Juan P. Rodrigo
Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model
Philipp Metzger, Sabrina V. Kirchleitner, Daniel F. R. Boehmer, Christine Hörth, Angelika Eisele, Steffen Ormanns, Matthias Gunzer, Maciej Lech, Kirsten Lauber, Stefan Endres, Peter Duewell, Max Schnurr, Lars M. König
A TLR4–TRIF-dependent signaling pathway is required for protective natural tumor-reactive IgM production by B1 cells
Allison M. Dyevoich, Nataya S. Disher, Marcela A. Haro, Karen M. Haas
Development of CDX-527: a bispecific antibody combining PD-1 blockade and CD27 costimulation for cancer immunotherapy
Laura A. Vitale, Li-Zhen He, Lawrence J. Thomas, Anna Wasiuk, Thomas O’Neill, Jenifer Widger, Andrea Crocker, Laura Mills-Chen, Eric Forsberg, Jeffrey Weidlick, Colleen Patterson, Russell A. Hammond, James Boyer, Crystal Sisson, Diego Alvarado, Joel Goldstein, Henry C. Marsh Jr., Tibor Keler
Antitumor efficacy of BAFF-R targeting CAR T cells manufactured under clinic-ready conditions
Zhenyuan Dong, Wesley A. Cheng, D. Lynne Smith, Brian Huang, Tiantian Zhang, Wen-Chung Chang, Xiuli Wang, Stephen J. Forman, Larry W. Kwak, Hong Qin
NKG2D-Fc fusion protein promotes antitumor immunity through the depletion of immunosuppressive cells
Po-Hao Feng, Brandon Lam, Ssu-Hsueh Tseng, Yu-Jui Kung, Emily Farmer, Max A. Cheng, Chien-Fu Hung
Sex differences in the association between tumor growth and T cell response in a melanoma mouse model
Panshak P. Dakup, Kenneth I. Porter, Alexander A. Little, Hui Zhang, Shobhan Gaddameedhi
Observations on neuroimmunomodulation as a novel therapeutic strategy in metastasis
Ashwin Kumaria