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Breast Cancer Research and Treatment

Issue 1/2011

Content (38 Articles)

Preclinical study

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer

Marleen Kok, Wilbert Zwart, Caroline Holm, Renske Fles, Michael Hauptmann, Laura J. Van’t Veer, Lodewyk F. A. Wessels, Jacques Neefjes, Olle Stål, Sabine C. Linn, Göran Landberg, Rob Michalides

Preclinical study

Loss of ICAM-1 signaling induces psoriasin (S100A7) and MUC1 in mammary epithelial cells

S. Petersson, E. Shubbar, M. Yhr, A. Kovacs, C. Enerbäck

Preclinical study

Immunoconjugated gold nanoshell-mediated photothermal ablation of trastuzumab-resistant breast cancer cells

Laura B. Carpin, Lissett R. Bickford, Germaine Agollah, Tse-Kuan Yu, Rachel Schiff, Yi Li, Rebekah A. Drezek

Preclinical study

Estrogen levels act as a rheostat on p53 levels and modulate p53-dependent responses in breast cancer cell lines

Lynnette Fernández-Cuesta, Suresh Anaganti, Pierre Hainaut, Magali Olivier

Preclinical study

Biological and clinical implications of nicastrin expression in invasive breast cancer

Aleksandra Filipović, Julian Hendrik Gronau, Andrew R. Green, Jayson Wang, Sabari Vallath, Dongmin Shao, Sabeena Rasul, Ian O. Ellis, Ernesto Yagüe, Justin Sturge, R. Charles Coombes

Preclinical study

Identification of genes associated with chemosensitivity to SAHA/taxane combination treatment in taxane-resistant breast cancer cells

Hyun Chang, Hei-Cheul Jeung, Je Jun Jung, Tae Soo Kim, Sun Young Rha, Hyun Cheol Chung

Preclinical study

Presence of Foxp3 expression in tumor cells predicts better survival in HER2-overexpressing breast cancer patients treated with neoadjuvant chemotherapy

Sylvain Ladoire, Laurent Arnould, Grégoire Mignot, Bruno Coudert, Cédric Rébé, Fanny Chalmin, Julie Vincent, Mélanie Bruchard, Bruno Chauffert, François Martin, Pierre Fumoleau, François Ghiringhelli

Preclinical study

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Ching-Shyang Chen, Chia-Hwa Lee, Chang-Da Hsieh, Chi-Tang Ho, Min-Hsiung Pan, Ching-Shui Huang, Shih-Hsin Tu, Ying-Jan Wang, Li-Ching Chen, Yu-Jia Chang, Po-Li Wei, Yi-Yuan Yang, Chih-Hsiung Wu, Yuan-Soon Ho

Preclinical study

Targeting trastuzumab-resistant breast cancer cells with a lentivirus engineered to bind antibodies that recognize HER-2

Kai-xin Zhang, Connie Kim, Elaine Chow, Irvin S. Y. Chen, William Jia, Paul S. Rennie

Clinical trial

Zoledronic acid prevents bone loss in premenopausal women with early breast cancer undergoing adjuvant chemotherapy: a phase III trial of the Korean Cancer Study Group (KCSG-BR06-01)

Jeong Eun Kim, Jin-Hee Ahn, Kyung Hae Jung, Sung-Bae Kim, Hwa Jung Kim, Keun-Suk Lee, Jung-Sil Ro, Yun-Hee Park, Jin-Suk Ahn, Young-Hyk Im, Seock-Ah Im, Moon-Hee Lee, Si-Young Kim

Clinical trial

High serum TGF-α predicts poor response to lapatinib and capecitabine in HER2-positive breast cancer

Jiyoung Rhee, Sae-Won Han, Yongjun Cha, Hye Seon Ham, Hwang-phill Kim, Do-Youn Oh, Seock-Ah Im, Jong-Wan Park, Jungsil Ro, Keun Seok Lee, In Hae Park, Young-Hyuck Im, Yung-Jue Bang, Tae-You Kim

Clinical trial

Adjuvant dose-dense doxorubicin plus cyclophosphamide followed by dose-dense nab-paclitaxel is safe in women with early-stage breast cancer: a pilot study

Nicholas Robert, Lea Krekow, Chris Stokoe, Alicia Clawson, Jose Iglesias, Joyce O’Shaughnessy

Clinical trial

Pure flat epithelial atypia (DIN 1a) on core needle biopsy: study of 60 biopsies with follow-up surgical excision

Vincent Lavoué, Claire Marie Roger, Mathieu Poilblanc, Nicolas Proust, Camille Monghal-Verge, Christine Sagan, Patrick Tas, Habiba Mesbah, Philippe Porée, Catherine Gay, Gilles Body, Jean Levêque

Clinical trial

Benefits of early and prolonged fulvestrant treatment in 848 postmenopausal advanced breast cancer patients

Mathias Warm, Ronald Kates, Friedrich Overkamp, Anke Thomas, Nadia Harbeck

Clinical trial

Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer

Claudine Isaacs, Pia Herbolsheimer, Minetta C. Liu, Mary Wilkinson, Yvonne Ottaviano, Gina G. Chung, Robert Warren, Jennifer Eng-Wong, Philip Cohen, Karen L. Smith, Karen Creswell, Antonella Novielli, Rebecca Slack

Clinical trial

Impact of treatment characteristics on response of different breast cancer phenotypes: pooled analysis of the German neo-adjuvant chemotherapy trials

Gunter von Minckwitz, Michael Untch, Eveline Nüesch, Sibylle Loibl, Manfred Kaufmann, Sherko Kümmel, Peter A. Fasching, Wolfgang Eiermann, Jens-Uwe Blohmer, Serban Dan Costa, Keyur Mehta, Jörn Hilfrich, Christian Jackisch, Bernd Gerber, Andreas du Bois, Jens Huober, Claus Hanusch, Gottfried Konecny, Werner Fett, Elmar Stickeler, Nadia Harbeck, Volkmar Müller, Peter Jüni

Epidemiology

RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects

Haiming Sun, Jing Bai, Feng Chen, Yan Jin, Yang Yu, Lianhong Jin, Songbin Fu

Epidemiology

Preventable breast cancer is postmenopausal

Kari Hemminki, Asta Försti, Jan Sundquist, Seyed Mohsen Mousavi

Epidemiology

No evidence of excess breast cancer risk among mutation-negative women from BRCA mutation-positive families

Larissa A. Korde, Christine M. Mueller, Jennifer T. Loud, Jeffery P. Struewing, Kathy Nichols, Mark H. Greene, Phuong L. Mai

Epidemiology

Lack of an association between AURKA T91A polymorphisms and breast cancer: a meta-analysis involving 32,141 subjects

Haiming Sun, Jing Bai, Feng Chen, Yan Jin, Yang Yu, Songbin Fu

Epidemiology

Associations between mammographic density and serum and dietary cholesterol

Ame-Lia Tamburrini, Christy G. Woolcott, Norman F. Boyd, Martin J. Yaffe, Tim Terry, Yutaka Yasui, Charlotte A. Jones, Scott B. Patten, Kerry S. Courneya, Christine M. Friedenreich

Epidemiology

Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk

Genevieve M. Monsees, Peter Kraft, Stephen J. Chanock, David J. Hunter, Jiali Han

Epidemiology

The association of SULT1A1 codon 213 polymorphism and breast cancer susceptibility: meta-analysis from 16 studies involving 23,445 subjects

Yiyi Sun, Zhihe Zang, Xiaohong Xu, Zhonglin Zhang, Ling Zhong, Wang Zan, Yan Zhao, Lin Sun

Epidemiology

Centrosome-related genes, genetic variation, and risk of breast cancer

J. E. Olson, X. Wang, V. S. Pankratz, Z. S. Fredericksen, C. M. Vachon, R. A. Vierkant, J. R. Cerhan, F. J. Couch

Epidemiology

No evidence of MMTV-like env sequences in specimens from the Australian Breast Cancer Family Study

Daniel J. Park, Melissa C. Southey, Graham G. Giles, John L. Hopper

Epidemiology

Aromatase immunoreactivity is increased in mammographically dense regions of the breast

Celine M. Vachon, Hironobu Sasano, Karthik Ghosh, Kathleen R. Brandt, David A. Watson, Carol Reynolds, Wilma L. Lingle, Paul E. Goss, Rong Li, Sarah E. Aiyar, Christopher G. Scott, V. Shane Pankratz, Richard J. Santen, James N. Ingle

Brief Report

No evidence for an association of human papillomavirus and breast carcinoma

Raimundo Gerônimo Silva Jr., Benedito Borges da Silva

Brief Report

A recombination-based method to characterize human BRCA1 missense variants

Lucia Guidugli, Chiara Rugani, Grazia Lombardi, Paolo Aretini, Alvaro Galli, Maria Adelaide Caligo

Brief Report

Regional and seasonal influence in patient’s toxicity to adjuvant chemotherapy for early breast cancer

Juan de la Haba-Rodríguez, Álvaro Rodríguez-Lescure, Amparo Ruiz, Emilio Alba, Lourdes Calvo, Eva Carrasco, Maria Jose Escudero, Miguel Martín

Brief Report

Comprehensive CYP2D6 genotype and adherence affect outcome in breast cancer patients treated with tamoxifen monotherapy

Alastair M. Thompson, Andrea Johnson, Philip Quinlan, Grantland Hillman, Marcel Fontecha, Susan E. Bray, Colin A. Purdie, Lee B. Jordan, Roberta Ferraldeschi, Ayshe Latif, Kirsten D. Hadfield, Robert B. Clarke, Linda Ashcroft, D. Gareth Evans, Anthony Howell, Michele Nikoloff, Jeffrey Lawrence, William G. Newman

Letter to the Editor

Presence of MMTV-like env gene sequences in human breast cancer

Beatriz G.-T. Pogo, Stella M. Melana, Heberth Moran, James F. Holland

Letter to the Editor

Same data sources, different pooled analysis result: the ongoing uncertainty in the subgroup analysis of RAD51 135G/C polymorphism and breast cancer risk

Pei-Hua Lu, Chen Li, Hong-Yi Zhou, Tong Wang, Chun-Qiang Chu, Wei Shen, Guo-Qing Tao

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine