Issue 2/2011
Content (55 Articles)
Abnormalities of T cell signaling in systemic lupus erythematosus
Vaishali R Moulton, George C Tsokos
The role of the Notch pathway in healthy and osteoarthritic articular cartilage: from experimental models to ex vivo studies
Nadia Sassi, Lilia Laadhar, Maha Driss, Meriam Kallel-Sellami, Slaheddine Sellami, Sondes Makni
The tumour-associated glycoprotein podoplanin is expressed in fibroblast-like synoviocytes of the hyperplastic synovial lining layer in rheumatoid arthritis
Anna-Karin H Ekwall, Thomas Eisler, Christian Anderberg, Chunsheng Jin, Niclas Karlsson, Mikael Brisslert, Maria I Bokarewa
Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
Zoe E Betteridge, Harsha Gunawardena, Neil J McHugh
Is Sjögren's syndrome a retroviral disease?
Nikolaos V Sipsas, Maria N Gamaletsou, Haralampos M Moutsopoulos
Contemporary epidemiology of gout in the UK general population
Lucía Cea Soriano, Dietrich Rothenbacher, Hyon K Choi, Luis A García Rodríguez
TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study
Aya Kawasaki, Hiroshi Furukawa, Yuya Kondo, Satoshi Ito, Taichi Hayashi, Makio Kusaoi, Isao Matsumoto, Shigeto Tohma, Yoshinari Takasaki, Hiroshi Hashimoto, Takayuki Sumida, Naoyuki Tsuchiya
Comparative efficacy of a secretory phospholipase A2 inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis
Liam G Coulthard, Jaclyn Costello, Brent Robinson, Ian A Shiels, Stephen M Taylor, Trent M Woodruff
Association between the PTPN22+1858 C/T polymorphism and psoriatic arthritis
Kristina Juneblad, Martin Johansson, Solbritt Rantapää-Dahlqvist, Gerd-Marie Alenius
Erratum to: mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis
Matthew R McCann, Roxana Monemdjou, Parisa Ghassemi-Kakroodi, Hassan Fahmi, Gemma Perez, Shangxi Liu, Xu Shi-wen, Sunil K Parapuram, Fumiaki Kojima, Christopher P Denton, David J Abraham, Johanne Martel-Pelletier, Leslie J Crofford, Andrew Leask, Mohit Kapoor
Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells
Toshio Kawamoto, Yoshiyuki Abe, Jun Ito, Fumihiko Makino, Yuko Kojima, Yoshihiko Usui, Juan Ma, Shinji Morimoto, Hideo Yagita, Ko Okumura, Yoshinari Takasaki, Hisaya Akiba
The role of synovial fluid markers of catabolism and anabolism in osteoarthritis, rheumatoid arthritis and asymptomatic organ donors
Rediet Kokebie, Rohit Aggarwal, Sukhwinderjit Lidder, Arnavaz A Hakimiyan, David C Rueger, Joel A Block, Susan Chubinskaya
Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat Gouty Arthritis by suppressing inflammation: results of a randomized, dose-ranging study
Naomi Schlesinger, Marc De Meulemeester, Andrey Pikhlak, A Eftal Yücel, Dominik Richard, Valda Murphy, Udayasankar Arulmani, Peter Sallstig, Alexander So
Response to 'Effect of etanercept in polymyalgia rheumatica: a randomized controlled trial'
Pippa Watson, Hill Gaston
Whole blood lead levels are associated with radiographic and symptomatic knee osteoarthritis: a cross-sectional analysis in the Johnston County Osteoarthritis Project
Amanda E Nelson, Xiaoyan A Shi, Todd A Schwartz, Jiu-Chiuan Chen, Jordan B Renner, Kathleen L Caldwell, Charles G Helmick, Joanne M Jordan
Risk factors for ANA positivity in healthy persons
Quan-Zhen Li, David R Karp, Jiexia Quan, Valerie K Branch, Jinchun Zhou, Yun Lian, Benjamin F Chong, Edward K Wakeland, Nancy J Olsen
Chromatin as a target antigen in human and murine lupus nephritis
Annica Hedberg, Elin S Mortensen, Ole P Rekvig
Intraarticular injection of hyaluronan prevents cartilage erosion, periarticular fibrosis and mechanical allodynia and normalizes stance time in murine knee osteoarthritis
Anna Plaas, Jun Li, Julie Riesco, Rosalina Das, John D Sandy, Andrew Harrison
TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis
Anak ASSK Dharmapatni, Malcolm D Smith, Tania N Crotti, Christopher A Holding, Cristina Vincent, Helen M Weedon, Andrew CW Zannettino, Timothy S Zheng, David M Findlay, Gerald J Atkins, David R Haynes
Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development
Alexandra Bäcklund, Meirav Holmdahl, Ragnar Mattsson, Katarina Håkansson, Veronica Lindström, Kutty Selva Nandakumar, Anders Grubb, Rikard Holmdahl
Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate
Yingjuan Lu, Torian W Stinnette, Elaine Westrick, Patrick J Klein, Mark A Gehrke, Vicky A Cross, Iontcho R Vlahov, Philip S Low, Christopher P Leamon
What do measurements of molecular biomarkers in different body fluids really tell us?
A Robin Poole
Biochemical markers of ongoing joint damage in rheumatoid arthritis - current and future applications, limitations and opportunities
Morten A Karsdal, Thasia Woodworth, Kim Henriksen, Walter P Maksymowych, Harry Genant, Philippe Vergnaud, Claus Christiansen, Tanja Schubert, Per Qvist, Georg Schett, Adam Platt, Anne-Christine Bay-Jensen
Antinuclear antibodies in healthy people: the tip of autoimmunity's iceberg?
David S Pisetsky
Trapped in a vicious loop: Toll-like receptors sustain the spontaneous cytokine production by rheumatoid synovium
Shahla Abdollahi-Roodsaz, Fons AJ van de Loo, Wim B van den Berg
Associations between the HLA-Apolymorphism and the clinical manifestations of Behcet's disease
Eun Ha Kang, Jeong Yeon Kim, Fujio Takeuchi, Joon Wan Kim, Kichul Shin, Eun Young Lee, Yun Jong Lee, Eun Bong Lee, Myoung Hee Park, Yeong Wook Song
Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis
Satoko Takei, Tomoaki Hoshino, Kazuko Matsunaga, Yuki Sakazaki, Masanori Sawada, Hanako Oda, Shin-ichi Takenaka, Haruki Imaoka, Takashi Kinoshita, Seiyo Honda, Hiroaki Ida, Taka-aki Fukuda, Hisamichi Aizawa
Response to 'Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomized study over 21 months'
Miguel A Gonzalez-Gay, Carlos Gonzalez-Juanatey, Jose A Miranda-Filloy, Javier Martin, Maria T Garcia-Unzueta, Javier Llorca
Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines
Hans-Georg Schaible, Andrea Ebersberger, Gabriel Natura
The role of the central nervous system in the generation and maintenance of chronic pain in rheumatoid arthritis, osteoarthritis and fibromyalgia
Yvonne C Lee, Nicholas J Nassikas, Daniel J Clauw
Soluble IL-18 receptor complex: a new star in the firmament of rheumatoid arthritis diagnosis?
Fons AJ van de Loo
Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects
Fernando M Pimentel-Santos, Dário Ligeiro, Mafalda Matos, Ana F Mourão, José Costa, Helena Santos, Anabela Barcelos, Fátima Godinho, Patricia Pinto, Margarida Cruz, João E Fonseca, Henrique Guedes-Pinto, Jaime C Branco, Matthew A Brown, Gethin P Thomas
Distinguishing fibromyalgia from rheumatoid arthritis and systemic lupus in clinical questionnaires: an analysis of the revised Fibromyalgia Impact Questionnaire (FIQR) and its variant, the Symptom Impact Questionnaire (SIQR), along with pain locations
Ronald Friend, Robert M Bennett
Regulation of chondrocyte gene expression by osteogenic protein-1
Susan Chubinskaya, Lori Otten, Stephan Soeder, Jeffrey A Borgia, Thomas Aigner, David C Rueger, Richard F Loeser
Relative percentage and zonal distribution of mesenchymal progenitor cells in human osteoarthritic and normal cartilage
David Pretzel, Stefanie Linss, Steffen Rochler, Michaela Endres, Christian Kaps, Saifeddin Alsalameh, Raimund W Kinne
Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus
Christian Lood, Martin Stenström, Helena Tydén, Birgitta Gullstrand, Eva Källberg, Tomas Leanderson, Lennart Truedsson, Gunnar Sturfelt, Fredrik Ivars, Anders A Bengtsson
Platelet-derived growth factor receptor-β and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosis-associated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive disease: a case-control study
Maria J Overbeek, Anco Boonstra, Alexandre E Voskuyl, Madelon C Vonk, Anton Vonk-Noordegraaf, Maria PA van Berkel, Wolter J Mooi, Ben AC Dijkmans, Laurens S Hondema, Egbert F Smit, Katrien Grünberg
Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis
Jun Wu, Carl Ekman, Andreas Jönsen, Gunnar Sturfelt, Anders A Bengtsson, Anders Gottsäter, Bengt Lindblad, Elisabet Lindqvist, Tore Saxne, Björn Dahlbäck
Underexpression of mitochondrial-DNA encoded ATP synthesis-related genes and DNA repair genes in systemic lupus erythematosus
Hooi-Ming Lee, Hidehiko Sugino, Chieko Aoki, Norihiro Nishimoto
Decrease in the incidence of total hip arthroplasties in patients with rheumatoid arthritis - results from a well defined population in south Sweden
Korosh Hekmat, Lennart Jacobsson, Jan-Åke Nilsson, Ingemar F Petersson, Otto Robertsson, Göran Garellick, Carl Turesson
Hyperuricemia and the risk for subclinical coronary atherosclerosis - data from a prospective observational cohort study
Eswar Krishnan, Bhavik J Pandya, Lorinda Chung, Omar Dabbous
Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases
Terrance P O'Hanlon, Lisa G Rider, Lu Gan, Rick Fannin, Richard S Paules, David M Umbach, Clarice R Weinberg, Ruchir R Shah, Deepak Mav, Mark F Gourley, Frederick W Miller
Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers
Saedis Saevarsdottir, Bo Ding, Kristjan Steinsson, Gerdur Grondal, Helgi Valdimarsson, Lars Alfredsson, Lars Klareskog, Leonid Padyukov
A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis
Kristine L Stump, Lily D Lu, Pawel Dobrzanski, Cynthia Serdikoff, Diane E Gingrich, Ben J Dugan, Thelma S Angeles, Mark S Albom, Mark A Ator, Bruce D Dorsey, Bruce A Ruggeri, Matthew M Seavey
A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity
Yang Feng, Jiayin Shen, Emily D Streaker, Michael Lockwood, Zhongyu Zhu, Philip S Low, Dimiter S Dimitrov
Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study
Hanns-Martin Lorenz, Wilhelm H Schmitt, Vladimir Tesar, Ulf Müller-Ladner, Ingo Tarner, Ingeborg A Hauser, Falk Hiepe, Tobias Alexander, Heike Woehling, Kyuichi Nemoto, Peter A Heinzel
Macrophage migration inhibitory factor enhances osteoclastogenesis through upregulation of RANKL expression from fibroblast-like synoviocytes in patients with rheumatoid arthritis
Hae-Rim Kim, Kyoung-Woon Kim, Hong Geun Jung, Kwang-Sup Yoon, Hye-Jwa Oh, Mi-La Cho, Sang-Heon Lee
Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine
Nina Ivanovska, Petya Dimitrova
Reproduction of overall spontaneous pain pattern by manual stimulation of active myofascial trigger points in fibromyalgia patients
Hong-You Ge, Ying Wang, César Fernández-de-las-Peñas, Thomas Graven-Nielsen, Bente Danneskiold-Samsøe, Lars Arendt-Nielsen
Osteoarthritis subpopulations and implications for clinical trial design
Sita MA Bierma-Zeinstra, Arianne P Verhagen