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Current Neurology and Neuroscience Reports
Published in: Current Neurology and Neuroscience Reports 7/2023

03-06-2023 | Apraxia

An Update on Apraxia of Speech

Authors: Rene L. Utianski, Keith A. Josephs

Published in: Current Neurology and Neuroscience Reports | Issue 7/2023

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Abstract

Purpose of Review

Apraxia of speech (AOS) is a motor speech disorder that has long been recognized to occur secondary to acute neurologic insults and, more recently, to neurodegenerative diseases as a harbinger for progressive supranuclear palsy and corticobasal syndrome. This article reviews recent findings regarding the clinic phenotypes of AOS, neuroimaging correlates, and the underlying disease processes.

Recent Findings

Two clinical subtypes of AOS map onto two underlying 4-repeat tauopathies. New imaging techniques have recently been applied to the study of progressive AOS. There is no data on the impact of behavioral intervention, although studies of nonfluent/agrammatic primary progressive aphasia that include patients with AOS suggest some benefit in speech intelligibility and maintenance.

Summary

While recent findings suggest subtypes of AOS exist that are linked to molecular pathology and have important implications for disease progression, further research is needed to assess outcome of behavioral and other types of intervention.
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Metadata
Title
An Update on Apraxia of Speech
Authors
Rene L. Utianski
Keith A. Josephs
Publication date
03-06-2023
Publisher
Springer US
Published in
Current Neurology and Neuroscience Reports / Issue 7/2023
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-023-01275-1

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