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Acta Neuropathologica

Issue 5/2018

Content (13 Articles)

Open Access Original Paper

Nodding syndrome in Uganda is a tauopathy

Michael S. Pollanen, Sylvester Onzivua, Janice Robertson, Paul M. McKeever, Francis Olawa, David L. Kitara, Amanda Fong

Open Access Original Paper

Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

Benjamin Falcon, Wenjuan Zhang, Manuel Schweighauser, Alexey G. Murzin, Ruben Vidal, Holly J. Garringer, Bernardino Ghetti, Sjors H. W. Scheres, Michel Goedert

Open Access Original Paper

Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy

Mariet Allen, Xue Wang, Daniel J. Serie, Samantha L. Strickland, Jeremy D. Burgess, Shunsuke Koga, Curtis S. Younkin, Thuy T. Nguyen, Kimberly G. Malphrus, Sarah J. Lincoln, Melissa Alamprese, Kuixi Zhu, Rui Chang, Minerva M. Carrasquillo, Naomi Kouri, Melissa E. Murray, Joseph S. Reddy, Cory Funk, Nathan D. Price, Todd E. Golde, Steven G. Younkin, Yan W. Asmann, Julia E. Crook, Dennis W. Dickson, Nilüfer Ertekin-Taner

Open Access Original Paper

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau

Jean-Philippe Courade, Rachel Angers, Georges Mairet-Coello, Nathalie Pacico, Kerry Tyson, Daniel Lightwood, Rebecca Munro, David McMillan, Robert Griffin, Terry Baker, Dale Starkie, Ruodan Nan, Marta Westwood, Marie-Laetitia Mushikiwabo, Sophie Jung, Geofrey Odede, Berni Sweeney, Andrew Popplewell, Gillian Burgess, Patrick Downey, Martin Citron

Open Access Original Paper

Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease

Eleanor K. Pickett, Jamie Rose, Caoimhe McCrory, Chris-Anne McKenzie, Declan King, Colin Smith, Thomas H. Gillingwater, Christopher M. Henstridge, Tara L. Spires-Jones

Open Access Original Paper

Opposite development of short- and long-range anterior cingulate pathways in autism

Basilis Zikopoulos, Xuefeng Liu, Justin Tepe, Iris Trutzer, Yohan J. John, Helen Barbas

Original Paper

DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome

Tareq A. Juratli, Devin McCabe, Naema Nayyar, Erik A. Williams, Ian M. Silverman, Shilpa S. Tummala, Alexandria L. Fink, Aymen Baig, Maria Martinez-Lage, Martin K. Selig, Ivanna V. Bihun, Ganesh M. Shankar, Tristan Penson, Matthew Lastrapes, Dirk Daubner, Matthias Meinhardt, Silke Hennig, Alexander B. Kaplan, Shingo Fujio, Benjamin M. Kuter, Mia S. Bertalan, Julie J. Miller, Julie M. Batten, Heather A. Ely, Jason Christiansen, Gustavo B. Baretton, Anat O. Stemmer-Rachamimov, Sandro Santagata, Miguel N. Rivera, Fred G. Barker II, Gabriele Schackert, Hiroaki Wakimoto, A. John Iafrate, Scott L. Carter, Daniel P. Cahill, Priscilla K. Brastianos

Original Paper

Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma

Damian Stichel, Azadeh Ebrahimi, David Reuss, Daniel Schrimpf, Takahiro Ono, Mitsuaki Shirahata, Guido Reifenberger, Michael Weller, Daniel Hänggi, Wolfgang Wick, Christel Herold-Mende, Manfred Westphal, Sebastian Brandner, Stefan M. Pfister, David Capper, Felix Sahm, Andreas von Deimling

Correspondence

cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

Daniel J. Brat, Kenneth Aldape, Howard Colman, Eric C. Holland, David N. Louis, Robert B. Jenkins, B. K. Kleinschmidt-DeMasters, Arie Perry, Guido Reifenberger, Roger Stupp, Andreas von Deimling, Michael Weller

Correspondence

On the origin of tau seeding activity in Alzheimer’s disease

Helmut Heinsen, Lea T. Grinberg

Correspondence

Rebuttal to Drs. Grinberg and Heinsen

Sarah K. Kaufman, Kelly Del Tredici, Heiko Braak, Marc I. Diamond