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01-12-2015 | Skeletal Biology and Regulation (MR Forwood and A Robling, Section Editors)

Vibration Therapy to Prevent Bone Loss and Falls: Mechanisms and Efficacy

Author: Belinda R. Beck

Published in: Current Osteoporosis Reports | Issue 6/2015

Abstract

A considerable volume of evidence has accumulated to suggest that whole-body vibration (WBV) may have a therapeutic role to play in the prevention of osteoporotic fracture, particularly for individuals who are unable to tolerate vigorous exercise interventions. There is moderate to strong evidence that WBV will prevent falls (likely due to enhanced neuromuscular function), but also some indication that the effects of WBV do not outstrip those of targeted exercise. Animal data indicates that WBV will also improve bone mass, including preventing loss due to hormone withdrawal, disuse and glucocorticoid exposure. Human trials, however, have produced equivocal outcomes for bone. Positive trends are apparent at the hip and spine, but shortcomings in study designs have limited statistical power. The mechanism of the vibration effect on bone tissue is likely to be mechanical coupling between an oscillating cell nucleus and the cytoskeleton. More robust dose-response human data are required before therapeutic guidelines can be developed.

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Title: Vibration Therapy to Prevent Bone Loss and Falls: Mechanisms and Efficacy
Author: Belinda R. Beck
Publication date: 01-12-2015
Publisher: Springer US
Published in: Current Osteoporosis Reports / Issue 6/2015
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-015-0294-8

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Vibration Therapy to Prevent Bone Loss and Falls: Mechanisms and Efficacy

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