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Open Access 01-12-2022 | Ventricular Septal Defect | Case report

Utility of thromboelastogram in cardiac surgery in Jacobsen syndrome associated with platelet dysfunction: a case report

Authors: Chikashi Takeda, Akiko Hirotsu, Gento Yasuhara, Akito Mizuno, Kenichiro Tatsumi, Shuji Kawamoto

Published in: JA Clinical Reports | Issue 1/2022

Abstract

Background

Jacobsen syndrome is a rare genetic disorder with multiple congenital anomalies and platelet abnormalities caused by chromosome 11 deletion.

Case presentation

A 7-month-old boy with thrombocytopenia underwent ventricular septal defect closure. At the beginning of surgery, the platelet count was 168 × 10³/μL, and heparinized kaolin with heparinase reaction time (HKH-R), which represents clot formation time, was prolonged at 30.4 min. Platelet transfusion was continued, and at the end of surgery, the platelet count and HKH-R values improved to 215 × 10³/μL and 15 min, respectively.

Conclusions

As anesthetic management of patients with abnormal platelet function, the viscoelasticity test might be useful in evaluating hemostatic capacity.

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Title: Utility of thromboelastogram in cardiac surgery in Jacobsen syndrome associated with platelet dysfunction: a case report
Authors: Chikashi Takeda
Akiko Hirotsu
Gento Yasuhara
Akito Mizuno
Kenichiro Tatsumi
Shuji Kawamoto
Publication date: 01-12-2022
Publisher: Springer Berlin Heidelberg
Keywords: Ventricular Septal Defect
Ventricular Septal Defect
Thrombocytopenia
Platelet Transfusion
Published in: JA Clinical Reports / Issue 1/2022
Electronic ISSN: 2363-9024
DOI: https://doi.org/10.1186/s40981-022-00557-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Utility of thromboelastogram in cardiac surgery in Jacobsen syndrome associated with platelet dysfunction: a case report

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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