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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 2/2010

01-04-2010 | Editorial

Vasculogenesis in rheumatoid arthritis

Authors: Zoltán Szekanecz, Alisa E Koch

Published in: Arthritis Research & Therapy | Issue 2/2010

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Abstract

Decreased number and impaired functions of endothelial progenitor cells (EPCs) leading to impaired vasculogenesis have been associated with rheumatoid arthritis (RA). Defective vasculogenesis has also been implicated in premature atherosclerosis in RA. Recently, early-outgrowth monocytic and late-outgrowth hemangioblastic EPC subsets have been characterized. Hemangioblastic EPCs may exert increased numbers in active RA and may play a role in vascular repair underlying RA.
Literature
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Metadata
Title
Vasculogenesis in rheumatoid arthritis
Authors
Zoltán Szekanecz
Alisa E Koch
Publication date
01-04-2010
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue 2/2010
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar2943

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