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Current Rheumatology Reports
Published in: Current Rheumatology Reports 10/2020

01-10-2020 | Vasculitis | Vasculitis (L Espinoza, Section Editor)

Vasculitides in HIV Infection

Authors: Luis E. Vega, Luis R. Espinoza

Published in: Current Rheumatology Reports | Issue 10/2020

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Abstract

Purpose of Review

To review the spectrum of vasculitides in HIV-infected patients and to identify the clinical features that characterize vasculitis in sero-positive HIV.

Recent Findings

Epidemiological studies conducted in the post-HAART era described the rarity of vasculitis in the setting of HIV-infected patients. A study identified histopathological features such as leukocytoclastic vasculitis of the vasa vasorum and adventitial inflammation in the large artery pathology of HIV-positive patients compared with HIV-negative patients with critical lower limb ischemia. A recent retrospective cohort study reported that HIV-positive patients with LVV developed more vascular complications, responded less to antiretroviral therapy, and had worse outcome than HIV-negative patients with LVV.

Summary

Vasculitides continue to be a rare disease in patients with HIV. The spectrum of vasculitis ranges from life-threatening conditions to relatively mild skin conditions. Recognizing vasculitis in the setting of HIV-positive patients is important because sometimes it require immunosuppressive treatment.
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Metadata
Title
Vasculitides in HIV Infection
Authors
Luis E. Vega
Luis R. Espinoza
Publication date
01-10-2020
Publisher
Springer US
Published in
Current Rheumatology Reports / Issue 10/2020
Print ISSN: 1523-3774
Electronic ISSN: 1534-6307
DOI
https://doi.org/10.1007/s11926-020-00945-0

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