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Published in: World Journal of Urology 11/2020

01-11-2020 | Urinary Tract Infection | Original Article

Laser enucleation of the prostate versus transurethral resection of the prostate: perioperative outcomes from the ACS NSQIP database

Authors: Nassib Abou Heidar, Muhieddine Labban, Vincent Misrai, Aurelie Mailhac, Hani Tamim, Albert El-Hajj

Published in: World Journal of Urology | Issue 11/2020

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Abstract

Purpose

To compare the perioperative outcomes associated with laser enucleation of the prostate (LEP) and transurethral resection of the prostate (TURP) using a national database.

Methods

The American College of Surgeons National Surgical Quality Improvement Program database was reviewed for patients who underwent TURP or LEP from 2008 to 2016. Baseline demographics, comorbidities, and predisposition to bleeding were compared between TURP and LEP. The 30-day perioperative outcomes including operative time, length of hospital stay (LOS), return to the operating room (OR), bleeding requiring transfusion, and organ system-specific complications were compared between the procedures. A multivariate logistic regression analysis was performed, adjusting for the type of surgery and other covariates.

Results

The series included 37,577 TURP and 2869 LEP procedures. While TURP was associated with a shorter operative time (55.20 ± 37.80 min) than LEP (102.80 ± 62.30 min), the latter was associated with a shorter hospital stay (1.29 ± 2.73 days) than TURP (2.05 ± 5.20 days). Compared to TURP, LEP had 0.52 (0.47–0.58) times the odds of a LOS > 1 day and 0.67 (0.54–0.83) times the odds of developing urinary tract infections. Nevertheless, no difference was found for other postoperative complications, need for transfusion, and return to OR.

Conclusion

Real-life data from a large national database confirmed that LEP is a safe and reproducible procedure to treat benign prostatic obstruction. Compared to TURP, LEP was associated with a lower rate of infectious complications and a shorter LOS at the expense of an increased operative time.
Footnotes
1
Partially dependent patients require assistance from another person for activities of daily activities. This category also includes those relying on prosthetics and devices. Totally dependent patients require total assistance for all activities.
 
Literature
1.
go back to reference Lukacs B, Cornu JN, Aout M, Tessier N, Hodee C, Haab F, Cussenot O, Merliere Y, Moysan V, Vicaut E (2013) Management of lower urinary tract symptoms related to benign prostatic hyperplasia in real-life practice in France: a comprehensive population study. Eur Urol 64(3):493–501CrossRefPubMed Lukacs B, Cornu JN, Aout M, Tessier N, Hodee C, Haab F, Cussenot O, Merliere Y, Moysan V, Vicaut E (2013) Management of lower urinary tract symptoms related to benign prostatic hyperplasia in real-life practice in France: a comprehensive population study. Eur Urol 64(3):493–501CrossRefPubMed
2.
go back to reference Wei JT, Calhoun E, Jacobsen SJ (2005) Urologic diseases in America project: benign prostatic hyperplasia. J Urol 173(4):1256–1261CrossRefPubMed Wei JT, Calhoun E, Jacobsen SJ (2005) Urologic diseases in America project: benign prostatic hyperplasia. J Urol 173(4):1256–1261CrossRefPubMed
3.
go back to reference Akman T, Binbay M, Tekinarslan E, Tepeler A, Akcay M, Ozgor F, Ugurlu M, Muslumanoglu A (2013) Effects of bipolar and monopolar transurethral resection of the prostate on urinary and erectile function: a prospective randomized comparative study. BJU Int 111(1):129–136CrossRefPubMed Akman T, Binbay M, Tekinarslan E, Tepeler A, Akcay M, Ozgor F, Ugurlu M, Muslumanoglu A (2013) Effects of bipolar and monopolar transurethral resection of the prostate on urinary and erectile function: a prospective randomized comparative study. BJU Int 111(1):129–136CrossRefPubMed
4.
go back to reference Kahokehr A, Gilling PJ (2014) Enucleation techniques for benign prostate obstruction: which one and why? Curr Opin Urol 24(1):49–55CrossRefPubMed Kahokehr A, Gilling PJ (2014) Enucleation techniques for benign prostate obstruction: which one and why? Curr Opin Urol 24(1):49–55CrossRefPubMed
5.
go back to reference Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S (2015) A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol 67(6):1066–1096CrossRefPubMed Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, McVary K, Novara G, Woo H, Madersbacher S (2015) A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol 67(6):1066–1096CrossRefPubMed
6.
go back to reference Roberts WW (2016) New technologies in benign prostatic hyperplasia management. Curr Opin Urol 26(3):254–258CrossRefPubMed Roberts WW (2016) New technologies in benign prostatic hyperplasia management. Curr Opin Urol 26(3):254–258CrossRefPubMed
7.
go back to reference Rivera M, Krambeck A, Lingeman J (2017) Holmium laser enucleation of the prostate in patients requiring anticoagulation. Curr Urol Rep 18(10):77CrossRefPubMed Rivera M, Krambeck A, Lingeman J (2017) Holmium laser enucleation of the prostate in patients requiring anticoagulation. Curr Urol Rep 18(10):77CrossRefPubMed
8.
go back to reference Yin L, Teng J, Huang CJ, Zhang X, Xu D (2013) Holmium laser enucleation of the prostate versus transurethral resection of the prostate: a systematic review and meta-analysis of randomized controlled trials. J Endourol 27(5):604–611CrossRefPubMed Yin L, Teng J, Huang CJ, Zhang X, Xu D (2013) Holmium laser enucleation of the prostate versus transurethral resection of the prostate: a systematic review and meta-analysis of randomized controlled trials. J Endourol 27(5):604–611CrossRefPubMed
9.
go back to reference Gilling PJ, Wilson LC, King CJ, Westenberg AM, Frampton CM, Fraundorfer MR (2012) Long-term results of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection of the prostate: results at 7 years. BJU Int 109(3):408–411CrossRefPubMed Gilling PJ, Wilson LC, King CJ, Westenberg AM, Frampton CM, Fraundorfer MR (2012) Long-term results of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection of the prostate: results at 7 years. BJU Int 109(3):408–411CrossRefPubMed
10.
go back to reference Wu WC, Schifftner TL, Henderson WG, Eaton CB, Poses RM, Uttley G, Sharma SC, Vezeridis M, Khuri SF, Friedmann PD (2007) Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. JAMA 297(22):2481–2488CrossRefPubMed Wu WC, Schifftner TL, Henderson WG, Eaton CB, Poses RM, Uttley G, Sharma SC, Vezeridis M, Khuri SF, Friedmann PD (2007) Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. JAMA 297(22):2481–2488CrossRefPubMed
11.
go back to reference Leichtle SW, Mouawad NJ, Lampman R, Singal B, Cleary RK (2011) Does preoperative anemia adversely affect colon and rectal surgery outcomes? J Am Coll Surg 212(2):187–194CrossRefPubMed Leichtle SW, Mouawad NJ, Lampman R, Singal B, Cleary RK (2011) Does preoperative anemia adversely affect colon and rectal surgery outcomes? J Am Coll Surg 212(2):187–194CrossRefPubMed
12.
go back to reference Madduri VKS, Bera MK, Pal DK (2016) Monopolar versus bipolar transurethral resection of prostate for benign prostatic hyperplasia: Operative outcomes and surgeon preferences, a real-world scenario. Urol Ann 8(3):291–296CrossRefPubMedPubMedCentral Madduri VKS, Bera MK, Pal DK (2016) Monopolar versus bipolar transurethral resection of prostate for benign prostatic hyperplasia: Operative outcomes and surgeon preferences, a real-world scenario. Urol Ann 8(3):291–296CrossRefPubMedPubMedCentral
13.
go back to reference Lerner LB, Rajender A (2015) Laser prostate enucleation techniques. Can J Urol 22(Suppl 1):53–59PubMed Lerner LB, Rajender A (2015) Laser prostate enucleation techniques. Can J Urol 22(Suppl 1):53–59PubMed
14.
go back to reference NSQIP A (2013) Variables and definitions. In: ACS NSQIP Operations Manual. pdf edn. 1–139 NSQIP A (2013) Variables and definitions. In: ACS NSQIP Operations Manual. pdf edn. 1–139
15.
go back to reference Bhojani N, Gandaglia G, Sood A, Rai A, Pucheril D, Chang SL, Karakiewicz PI, Menon M, Olugbade K Jr, Ruhotina N et al (2014) Morbidity and mortality after benign prostatic hyperplasia surgery: data from the American College of Surgeons national surgical quality improvement program. J Endourol 28(7):831–840CrossRefPubMed Bhojani N, Gandaglia G, Sood A, Rai A, Pucheril D, Chang SL, Karakiewicz PI, Menon M, Olugbade K Jr, Ruhotina N et al (2014) Morbidity and mortality after benign prostatic hyperplasia surgery: data from the American College of Surgeons national surgical quality improvement program. J Endourol 28(7):831–840CrossRefPubMed
16.
go back to reference Anderson BB, Heiman J, Large T, Lingeman J, Krambeck A (2019) Trends and perioperative outcomes across major benign prostatic hyperplasia procedures from the ACS-NSQIP 2011–2015. J Endourol 33(1):62–68CrossRefPubMed Anderson BB, Heiman J, Large T, Lingeman J, Krambeck A (2019) Trends and perioperative outcomes across major benign prostatic hyperplasia procedures from the ACS-NSQIP 2011–2015. J Endourol 33(1):62–68CrossRefPubMed
17.
go back to reference Monn MF, El Tayeb M, Bhojani N, Mellon MJ, Sloan JC, Boris RS, Lingeman JE (2015) Predictors of enucleation and morcellation time during holmium laser enucleation of the prostate. Urology 86(2):338–342CrossRefPubMed Monn MF, El Tayeb M, Bhojani N, Mellon MJ, Sloan JC, Boris RS, Lingeman JE (2015) Predictors of enucleation and morcellation time during holmium laser enucleation of the prostate. Urology 86(2):338–342CrossRefPubMed
18.
go back to reference Misrai V, Kerever S, Phe V, Zorn KC, Peyronnet B, Roupret M (2016) Direct comparison of GreenLight Laser XPS photoselective prostate vaporization and GreenLight laser en bloc enucleation of the prostate in enlarged glands greater than 80 ml: a study of 120 patients. J Urol 195(4 Pt 1):1027–1032CrossRefPubMed Misrai V, Kerever S, Phe V, Zorn KC, Peyronnet B, Roupret M (2016) Direct comparison of GreenLight Laser XPS photoselective prostate vaporization and GreenLight laser en bloc enucleation of the prostate in enlarged glands greater than 80 ml: a study of 120 patients. J Urol 195(4 Pt 1):1027–1032CrossRefPubMed
19.
go back to reference Elterman DS, Chughtai B, Lee R, Kurlander L, Yip-Bannicq M, Kaplan SA, Te AE (2013) Comparison of techniques for transurethral laser prostatectomy: standard photoselective vaporization of the prostate versus transurethral laser enucleation of the prostate. J Endourol 27(6):751–755CrossRefPubMed Elterman DS, Chughtai B, Lee R, Kurlander L, Yip-Bannicq M, Kaplan SA, Te AE (2013) Comparison of techniques for transurethral laser prostatectomy: standard photoselective vaporization of the prostate versus transurethral laser enucleation of the prostate. J Endourol 27(6):751–755CrossRefPubMed
20.
go back to reference Elmansy H, Baazeem A, Kotb A, Badawy H, Riad E, Emran A, Elhilali M (2012) Holmium laser enucleation versus photoselective vaporization for prostatic adenoma greater than 60 ml: preliminary results of a prospective, randomized clinical trial. J Urol 188(1):216–221CrossRefPubMed Elmansy H, Baazeem A, Kotb A, Badawy H, Riad E, Emran A, Elhilali M (2012) Holmium laser enucleation versus photoselective vaporization for prostatic adenoma greater than 60 ml: preliminary results of a prospective, randomized clinical trial. J Urol 188(1):216–221CrossRefPubMed
21.
go back to reference Gilfrich C, Leicht H, Fahlenbrach C, Jeschke E, Popken G, Stolzenburg JU, Weissbach L, Zastrow C, Gunster C (2016) Morbidity and mortality after surgery for lower urinary tract symptoms: a study of 95 577 cases from a nationwide German health insurance database. Prostate Cancer Prostatic Dis 19(4):406–411CrossRefPubMed Gilfrich C, Leicht H, Fahlenbrach C, Jeschke E, Popken G, Stolzenburg JU, Weissbach L, Zastrow C, Gunster C (2016) Morbidity and mortality after surgery for lower urinary tract symptoms: a study of 95 577 cases from a nationwide German health insurance database. Prostate Cancer Prostatic Dis 19(4):406–411CrossRefPubMed
22.
go back to reference Kreydin EI, Chyu J, Lerner L (2018) Laser prostate ablation and enucleation: analysis of a national cohort. Int J Urol 25(6):549–553CrossRefPubMed Kreydin EI, Chyu J, Lerner L (2018) Laser prostate ablation and enucleation: analysis of a national cohort. Int J Urol 25(6):549–553CrossRefPubMed
23.
go back to reference Malik RD, Wang CE, Lapin B, Gerber GS, Helfand BT (2015) Comparison of patients undergoing laser vaporization of the prostate versus TURP using the ACS-NSQIP database. Prostate Cancer Prostatic Dis 18(1):18–24CrossRefPubMed Malik RD, Wang CE, Lapin B, Gerber GS, Helfand BT (2015) Comparison of patients undergoing laser vaporization of the prostate versus TURP using the ACS-NSQIP database. Prostate Cancer Prostatic Dis 18(1):18–24CrossRefPubMed
24.
go back to reference Kampantais S, Dimopoulos P, Tasleem A, Acher P, Gordon K, Young A (2018) Assessing the learning curve of holmium laser enucleation of prostate (HoLEP). A systematic review. Urology 120:9–22CrossRefPubMed Kampantais S, Dimopoulos P, Tasleem A, Acher P, Gordon K, Young A (2018) Assessing the learning curve of holmium laser enucleation of prostate (HoLEP). A systematic review. Urology 120:9–22CrossRefPubMed
25.
go back to reference Foster HE, Barry MJ, Dahm P, Gandhi MC, Kaplan SA, Kohler TS, Lerner LB, Lightner DJ, Parsons JK, Roehrborn CG et al (2018) Surgical management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA Guideline. J Urol 200(3):612–619CrossRefPubMed Foster HE, Barry MJ, Dahm P, Gandhi MC, Kaplan SA, Kohler TS, Lerner LB, Lightner DJ, Parsons JK, Roehrborn CG et al (2018) Surgical management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA Guideline. J Urol 200(3):612–619CrossRefPubMed
26.
go back to reference Marien T, Kadihasanoglu M, Miller NL (2016) Holmium laser enucleation of the prostate: patient selection and perspectives. Res Rep Urol 8:181–192PubMedPubMedCentral Marien T, Kadihasanoglu M, Miller NL (2016) Holmium laser enucleation of the prostate: patient selection and perspectives. Res Rep Urol 8:181–192PubMedPubMedCentral
27.
go back to reference Alexander CE, Scullion MM, Omar MI, Yuan Y, Mamoulakis C, N'Dow JM, Chen C, Lam TB (2019) Bipolar versus monopolar transurethral resection of the prostate for lower urinary tract symptoms secondary to benign prostatic obstruction. Cochrane Database Syst Rev 12:9629 Alexander CE, Scullion MM, Omar MI, Yuan Y, Mamoulakis C, N'Dow JM, Chen C, Lam TB (2019) Bipolar versus monopolar transurethral resection of the prostate for lower urinary tract symptoms secondary to benign prostatic obstruction. Cochrane Database Syst Rev 12:9629
Metadata
Title
Laser enucleation of the prostate versus transurethral resection of the prostate: perioperative outcomes from the ACS NSQIP database
Authors
Nassib Abou Heidar
Muhieddine Labban
Vincent Misrai
Aurelie Mailhac
Hani Tamim
Albert El-Hajj
Publication date
01-11-2020
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 11/2020
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-020-03100-7

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