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Gut Pathogens
Published in: Gut Pathogens 1/2021

Open Access 01-12-2021 | Ulcerative Colitis | Review

The role of mycobiota-genotype association in inflammatory bowel diseases: a narrative review

Authors: Elaheh Mahmoudi, Sayed-Hamidreza Mozhgani, Niusha Sharifinejad

Published in: Gut Pathogens | Issue 1/2021

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Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory disease affecting various parts of the gastrointestinal tract. A majority of the current evidence points out the involvement of intestinal dysbiosis in the IBD pathogenesis. Recently, the association of intestinal fungal composition With IBD susceptibility and severity has been reported. These studies suggested gene polymorphisms in the front line of host defense against intestinal microorganisms are considered to play a role in IBD pathogenesis. The studies have also detected increased susceptibility to fungal infections in patients carrying IBD-related mutations. Therefore, a literature search was conducted in related databases to review articles addressing the mycobiota-genotype association in IBD.
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Metadata
Title
The role of mycobiota-genotype association in inflammatory bowel diseases: a narrative review
Authors
Elaheh Mahmoudi
Sayed-Hamidreza Mozhgani
Niusha Sharifinejad
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Gut Pathogens / Issue 1/2021
Electronic ISSN: 1757-4749
DOI
https://doi.org/10.1186/s13099-021-00426-4

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