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BMC Gastroenterology
Published in: BMC Gastroenterology 1/2023

Open Access 01-12-2023 | Ulcerative Colitis | Research article

Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study

Authors: Severin A. Lautenschlager, Mamadou Pathé Barry, Gerhard Rogler, Luc Biedermann, Philipp Schreiner, Alexander R. Siebenhüner, Swiss IBD Cohort Study Group

Published in: BMC Gastroenterology | Issue 1/2023

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Abstract

Background

Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn’s disease and ulcerative colitis.

Methods

2294 patients from the Swiss IBD Cohort Study received a questionnaire regarding physical activity, nutritional habits and status of weight. In addition, a control group was formed comprising patients’ childhood friends, who grew up in a similar environment.

Results

Overall, 1111 questionnaires were returned (response rate: 48.4%). Significantly more patients with inflammatory bowel disease reported no regular practice of sport during childhood and beginning of adulthood compared to the control group (p = 0.0001). No association between intake of refined sugar and onset of inflammatory bowel disease was observed. More patients with Crohn’s disease compared to ulcerative colitis and controls suffered from overweight during childhood (12.8% vs. 7.7% and 9.7%, respectively; p = 0.027).

Conclusions

Our study underlines the relevance of environmental factors in the development of inflammatory bowel disease. Our results imply a protective effect of physical activity regarding the onset of inflammatory bowel disease.
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Metadata
Title
Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study
Authors
Severin A. Lautenschlager
Mamadou Pathé Barry
Gerhard Rogler
Luc Biedermann
Philipp Schreiner
Alexander R. Siebenhüner
Swiss IBD Cohort Study Group
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2023
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-023-02692-9

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