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clinical 

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  1. Journal

    Allergy, Asthma & Clinical Immunology

    A high-visibility platform for the dissemination of allergy and clinical immunology research, Allergy, Asthma & Clinical Immunology is the official journal of the Canadian Society of Allergy and Clinical Immunology. Providing rapid and rigorous …

  2. Open Access 16-05-2024 | Antiemetic Therapy | Online First

    2023 Japan Society of clinical oncology clinical practice guidelines update for antiemesis

    The Japan Society of Clinical Oncology Guidelines for Antiemetic Therapy was developed to appropriately evaluate and manage chemotherapy-induced nausea and vomiting and improve treatment efficacy, thereby improving patient quality of life (QOL) …

  3. Open Access 14-05-2024 | Heart Failure | Online First

    Advances in Clinical Cardiology 2023: A Summary of Key Clinical Trials

    In 2023, several landmark trials with the potential to change clinical practice were presented at major international meetings including the American College of Cardiology (ACC), European Association for Percutaneous Cardiovascular Interventions …

  4. Open Access 01-12-2024 | Meningitis | OriginalPaper

    Neurobrucellosis: laboratory features, clinical characteristics, antibiotic treatment, and clinical outcomes of 21 patients

    Brucella is a genus of Gram-negative bacteria that settle in cells and are commonly classified into sheep-type and bovine-type bacteria. The zoonosis caused by Brucella is called ‘brucellosis’, which is also known as ‘wavy fever’, ‘Mediterranean …

  5. 14-05-2024 | Meningioma | Online First

    Implications and interchangeability of meningioma biomarkers for clinical trials and clinical practice

  6. Open Access 01-12-2024 | Human Immunodeficiency Virus | OriginalPaper

    Demographic and clinical factors correlated with clinical outcomes among people with HIV treated by antiretroviral therapy: a retrospective cohort study

    As antiretroviral therapy (ART) continues to be promoted and optimized, mortality associated with HIV/AIDS has decreased. In China, although the number of HIV-related deaths increased from 5,485 in 2007 to 18,737 in 2019, the overall morality rate …

  7. Open Access 01-12-2024 | COVID-19 | OriginalPaper

    Effect of degalactosylated bovine glycoprotein formulations MAF and M сapsules on lymphopenia and clinical outcomes in hospitalized COVID-19 patients: a randomized clinical trial

    MAF capsules and M capsules are dietary supplements produced by Saisei Pharma, Japan. They are designated to modulate the mucosal immunity of the intestine. The main active ingredients of both products are vitamin D binding protein (VDBP) and …

  8. 01-06-2024 | OriginalPaper

    Implant stability and clinical outcome between implant placement using internal sinus floor elevation with alloplastic bone material grafting and without grafting: A 1-year randomized clinical trial

    Insufficient vertical bone height of posterior maxilla and poor bone quality may result in a critical problem for dental implant placement due to pneumatization of maxillary sinus [ 1 , 2 ].

  9. Open Access 13-04-2024 | Gastrointestinal Stromal Tumor | OriginalPaper

    English version of Japanese Clinical Practice Guidelines 2022 for gastrointestinal stromal tumor (GIST) issued by the Japan Society of Clinical Oncology

    The Japan Society of Clinical Oncology Clinical Practice Guidelines 2022 for gastrointestinal stromal tumor (GIST) have been published in accordance with the Minds Manual for Guideline Development 2014 and 2017. A specialized team independent of …

  10. 30-01-2024 | Amphotericin B | ReviewPaper

    Clinical treatment of cryptococcal meningitis: an evidence-based review on the emerging clinical data

    Cryptococcal meningitis (CM) is a fatal fungal central nervous system (CNS) infection caused by Cryptococcus infecting the meninges and/or brain parenchyma, with fever, headache, neck stiffness, and visual disturbances as the primary clinical

  11. Open Access 03-05-2024 | Atopic Dermatitis | OriginalPaper

    Lebrikizumab Provides Rapid Clinical Responses Across All Eczema Area and Severity Index Body Regions and Clinical Signs in Adolescents and Adults with Moderate-to-Severe Atopic Dermatitis

    This article is published with digital features, including an animation, to facilitate understanding of the article. To view digital features for this article go to https://doi.org/10.6084/m9.figshare.25533682 …

  12. 18-04-2024 | Warfarin | OriginalPaper

    Pharmacogenetic guided versus standard warfarin dosing for routine clinical care with its pharmacoeconomic impact: a randomized controlled clinical trial

    Warfarin still plays a role in the era of novel direct oral anticoagulants [ 1 ]. The possible reasons could be lower cost, wide availability, long clinical experience, and preferential use in prosthetic heart valve patients, children, and those …

  13. Journal

    Clinical Reviews in Allergy & Immunology

    Readers will find the journal of value in elucidating the impact of novel data on clinical management against the background of advances such as the development of standardized protocols for allergy skin testing and challenge procedures and improved understanding of cell biology.

  14. 30-03-2024 | OriginalPaper

    Are orthopedic clinical trials representative? An analysis of race and ethnicity reported in clinical trials between 2007 and 2022

    Running title: representation of clinical trials in orthopedic surgery

    Although race and ethnicity have been demonstrated to be independent predictors of healthcare outcomes [ 1 – 4 ], public reporting of race and ethnicity for United States-based clinical trial participants has only recently been required [ 5 ]. In …

  15. Open Access 01-12-2024 | COVID-19 | OriginalPaper

    A randomized clinical trial investigating the impact of magnesium supplementation on clinical and biochemical measures in COVID-19 patients

    The global outbreak of COVID-19 caused by the SARS-CoV-2 virus has presented an unprecedented challenge to public health worldwide, prompting an urgent search for effective treatment strategies [ 1 ]. As of March 19, 2023, the worldwide …

  16. Open Access 22-05-2024 | Granuloma Annulare | Online First

    Granuloma Annulare: A Clinical Update

  17. 02-05-2024 | Filgrastim | OriginalPaper

    Therapeutic use of granulocyte colony-stimulating factor (G-CSF) in patients with febrile neutropenia: a comprehensive systematic review for clinical practice guidelines for the use of G-CSF 2022 from the Japan Society of Clinical Oncology

    Febrile neutropenia (FN) is a common complication among patients undergoing chemotherapy, with incidence rates ranging from 0.8 to 20.6%, and influenced by various factors such as treatment regimens and patient backgrounds [ 1 – 3 ]. FN is notably …

  18. Open Access 01-06-2024 | Online First

    SEOM clinical guidelines for cancer anorexia-cachexia syndrome (2023)

    Cancer-related anorexia-cachexia syndrome (CACS) is a debilitating condition afflicting up to 80% of advanced-stage cancer patients. Characterized by progressive weight loss, muscle wasting, and metabolic abnormalities, CACS significantly …

  19. 05-04-2024 | Filgrastim | OriginalPaper

    Effectiveness of G-CSF in chemotherapy for digestive system tumors: a systematic review of the Clinical Practice Guidelines for the Use of G-CSF 2022 delineated by the Japan Society of Clinical Oncology

    The digestive system is a major source of cancer, with colorectal cancer being the most commonly diagnosed type in Japan in the year 2019 [ 1 ]. The development of cancer chemotherapy has significantly improved the prognosis of cancer patients; …

  20. Open Access 01-12-2024 | OriginalPaper

    Improving routine use of clinical pathway decision support through integration of an EHR with a clinical library resource designed to provide evidence-based guidance within oncology workflows

    • Research has shown that consulting evidence-based treatment pathways for cancer can help physicians keep current with new scientific discoveries and leads to better patient outcomes. • We designed treatment pathways that would be easily …

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