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Vulvar Cancer 

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  1. Open Access 01-05-2024 | Vulvar Cancer | OriginalPaper

    Implementation of quality indicators for vulvar cancer in gynaecological cancer centres certified by the German Cancer Society (DKG)

    Vulvar cancer (VC) is a rare malignant disease of the lower genital tract. The majority of vulvar cancer are vulvar squamous cell carcinoma (VSCC) (< 95%) (Diagnosis, Therapy, and Follow-Up Care of Vulvar Cancer and its Precursors 2015 ). The …

  2. Open Access 03-04-2024 | Vulvar Cancer | Online First

    Significance of definitive concurrent chemoradiotherapy for vulvar cancer: a Japanese Gynecologic Oncology Group nationwide survey study

    Vulvar cancer (VC) is a rare gynecological disease. There is a 30-fold variation in incidence rates worldwide, with the highest reported in South African data (age-standardized incidence rates; ASR, 7.2 per 100,000 inhabitants). However, in …

  3. 03-01-2024 | Vulvar Cancer | ReviewPaper

    Sentinel Lymph Node Evaluation in Early-Stage Vulvar Cancer

    Sentinel lymph node mapping (SLNM) and dissection (SLND) should be used as an alternative to full inguinofemoral lymph node dissection (IFLND) in select patients with early-stage vulvar cancer. IFLND is associated with high postoperative …

  4. Open Access 12-09-2023 | Vulvar Cancer | OriginalPaper

    Definitive chemoradiation in vulvar squamous cell carcinoma: outcome and toxicity from an observational multicenter Italian study on vulvar cancer (OLDLADY 1.1)

    Vulvar cancer is a rare disease affecting elderly women and representing about 5% of gynaecological cancers [ 1 , 2 ]. The treatment of loco-regional advanced carcinoma of the vulva (LAVC) is a challenge for both gynaecologic and radiation …

  5. Open Access 01-12-2023 | Vulvar Cancer | OriginalPaper

    Factors associated with vulvar cancer from 2005 to 2021 in Togo, sub-Saharan Africa

    Vulvar cancer is a malignant tumor proliferation that originates from various structures of the vulva [ 1 ]. Cancers, including vulvar cancer, are part of the broader category of non-communicable diseases and pose a significant public health …

  6. Open Access 14-07-2023 | Vulvar Cancer | OriginalPaper

    Digital droplet PCR-based quantification of ccfHPV-DNA as liquid biopsy in HPV-driven cervical and vulvar cancer

    More than 99% of cervical cancers and up to 40% of vulvar cancers are human papillomavirus (HPV) related (Zhang et al. 2018 ; Schnürch et al. 2015 ). The most frequent HPV subtypes are HPV 16 and 18 (Burd 2003 ). During the past decades, additional …

  7. Open Access 27-11-2022 | Vulvar Cancer | OriginalPaper

    Prostaglandin E2 receptor EP1 expression in vulvar cancer

    Vulvar carcinoma is a relatively rare disease, being the fifth most common gynecological tumor worldwide (International Agency for Research on Cancer 2020 ). Squamous cell carcinoma (SCC) is its most common histologic subgroup, representing around …

  8. 28-01-2023 | Melanoma | ReviewPaper

    Assessment and Reporting of Perioperative Adverse Events and Complications in Patients Undergoing Inguinal Lymphadenectomy for Melanoma, Vulvar Cancer, and Penile Cancer: A Systematic Review and Meta-analysis

    Melanoma, penile, and vulvar cancers represent approximately 0.6–6% of all malignancies in the United States. Cumulatively, a total of 108.180 new cases are expected in 2022 [ 1 ].

  9. Open Access 01-12-2022 | Vulvar Cancer | OriginalPaper

    Cervical, vaginal and vulvar cancer incidence and survival trends in Denmark, Finland, Norway and Sweden with implications to treatment

    More than half million cervical cancers are annually diagnosed in the world, a large majority of them in developing countries where cervical cancer ranks second after breast cancer [ 1 ]. Although human papilloma virus (HPV) is the major risk …

  10. Open Access 01-12-2022 | Human Papillomavirus | OriginalPaper

    Vulvar neuroendocrine carcinoma that is independent of merkel cell polyomavirus and human papillomavirus suggests endometrial cancer recurrence: a case report

    High-grade neuroendocrine carcinomas (HGNECs) of the vulva are extremely rare, but when they occur, they usually present as aggressive neoplasms [ 1 ]. These tumors can be further classified into Merkel cell carcinoma, small cell neuroendocrine …

  11. 01-11-2022 | Vulvar Cancer | OriginalPaper

    Observational multicenter Italian study on vulvar cancer adjuvant radiotherapy (OLDLADY 1.2): a cooperation among AIRO Gyn, MITO and MaNGO groups

    Vulvar carcinoma (VC) accounts for 3 to 5% of all gynecologic malignancies and 1% of all cancers in women. [ 1 ]. Ninety percent of VC histological subtypes are squamous cell carcinoma (SCC), with strong trend toward locoregional dissemination [ 2 …

  12. 21-04-2023 | Vulvar Cancer | Erratum

    Correction to: Radiation therapy for vulvar cancer: consensus guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology. Part 1: clinical recommendations

  13. 24-03-2023 | Brachytherapy | OriginalPaper

    Radiation therapy for vulvar cancer: consensus guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology. Part 1: clinical recommendations

    Vulvar cancer is a rare type of cancer, accounting for approximately 4% of all gynaecologic malignancies worldwide. Despite its relative rarity, the incidence of vulvar cancer has risen by about 0.6% per year over the last decade [ 1 ].

  14. 24-03-2023 | Brachytherapy | OriginalPaper

    Radiation therapy for vulvar cancer: consensus technical guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology. Part 2: radiotherapy recommendations

    Vulvar cancer is a relatively rare neoplasm, accounting for approximately 5% of all gynaecological malignancies. Radiotherapy (RT) plays an important role in the treatment of vulvar cancer, both as an adjuvant treatment after surgery and for the …

  15. Open Access 01-12-2020 | Human Papillomavirus | OriginalPaper

    Role of human papillomavirus infection in the etiology of vulvar cancer in Italian women

    Vulvar squamous cell carcinoma (VSCC) is a rare tumor of the female genital tract, accounting for about 5% of all gynecological malignancies [ 1 , 2 ]. In North America, the incidence of VSCC has increased by 0.6% annually in the past decade [ 1 …

  16. 01-10-2020 | Triage | OriginalPaper

    Personalizing vulvar cancer workflow in COVID-19 era: a proposal from Vul.Can MDT

    The outbreak of the novel Coronavirus disease 2019 (COVID-19), consisting in a severe acute respiratory syndrome often associated to multiple organ dysfunction, has rapidly spread globally, being declared a pandemic by the World Health …

  17. Open Access 01-12-2022 | Metastasis | OriginalPaper

    Vulvar cancer during pregnancy and/or breastfeeding: a report of five cases from a single center study at the University Hospital of Düsseldorf

    In non-pregnant women, vulvar cancer (VC) is the fourth most common gynecological cancer, following cervical, uterine and ovarian cancer [ 1 – 6 ]. Common malignancies reported during pregnancy are breast cancer (46%) and hematological malignancies …

  18. Open Access 01-01-2022 | Computed Tomography | OriginalPaper

    Clinical and prognostic 18F-FDG PET/CT role in recurrent vulvar cancer: a multicentric experience

    Vulvar cancer (VC) is a rare gynecologic malignancy, with an incidence rate of 1.5–2.4 per 100,000 women per year [ 1 , 2 ]. Vulvar squamous cell carcinoma is the most common histotype followed by melanoma, basal cell carcinoma, adenocarcinoma and …

  19. 24-05-2022 | Vulvar Cancer | ReviewPaper

    Detection of sentinel lymph node in vulvar cancer using 99mTc-labeled colloid lymphoscintigraphy, blue dye, and indocyanine-green fluorescence: a meta-analysis of studies published in 2010–2020

    Vulvar cancer is a rare tumor and accounts for 4% of all gynecological malignancies. The tumor prevalence is higher in elderly patients, and the mean age at diagnosis is 68 years. Most vulvar cancers are diagnosed at an early stage, and only …

  20. Vulvar cancer staging: guidelines of the European Society of Urogenital Radiology (ESUR)

    MRI is the modality of choice for local staging of vulvar cancer. T2WI, DWI-MRI, and DCE-MR are recommended. The most widely accepted criterion for inguinofemoral lymphadenopathy is short-axis > 1 cm. The most specific criterion for inguinofemoral …

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