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Visceral Leishmaniasis 

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  1. 12-03-2024 | Visceral Leishmaniasis | OriginalPaper

    Secondary hemophagocytic lymphohistiocytosis in pediatric patients with visceral leishmaniasis and Epstein-Barr virus infection

    Visceral leishmaniasis-associated hemophagocytic lymphohistiocytosis (VL-HLH) is indistinguishable from those of HLH of other etiologies due to the overlap symptoms, posing a serious threat to life. In this study, we aimed to provide insights for …

  2. Open Access 01-12-2024 | Visceral Leishmaniasis | OriginalPaper

    Association between living in the endemic area and level of knowledge of visceral leishmaniasis

    Visceral leishmaniasis (VL), the most serious form of leishmaniasis, is caused by Leishmania parasites and is characterized as an infectious, systemic, zoonotic, vector-borne, and neglected tropical disease [ 1 , 2 ]. VL is transmitted by species …

  3. Open Access 01-12-2024 | Visceral Leishmaniasis | OriginalPaper

    Visceral leishmaniasis misdiagnosed as an upper respiratory infection and iron-deficiency anemia in a 20-month-old male patient: a case report

    Pancytopenia is an important clinical-hematological presentation, in which all three key peripheral blood lineage is reduced, including red blood cells, white blood cells, and platelets [ 1 ]. Prompt recognition of the underlying cause of …

  4. 28-09-2023 | Leishmania | OriginalPaper

    Delayed diagnosis among patients with visceral leishmaniasis

    We aimed to estimate the diagnostic latency of patients with visceral leishmaniasis (VL). A monocentric retrospective observational study was conducted including all confirmed cases of VL diagnosed from January 2005 to March 2022. Epidemiological …

  5. Open Access 01-12-2023 | Leishmania | OriginalPaper

    Accuracy of the direct agglutination test for diagnosis of visceral leishmaniasis: a systematic review and meta-analysis

    Leishmaniasis is a vector-borne disease caused by the protozoan parasite of the genus Leishmania. The parasite is transmitted by the bite of female phlebotomine sand flies [ 1 ]. There are three main clinical forms of leishmaniasis: cutaneous …

  6. Open Access 01-12-2023 | Amphotericin B | OriginalPaper

    Factors associated with relapse and hospital death in patients coinfected with visceral leishmaniasis and HIV: a longitudinal study

    Visceral leishmaniasis (VL) is an infectious disease caused by protozoa of the genus Leishmania [ 1 ]. It occurs mainly in tropical and subtropical areas, with higher rates in populations that are in situations of social vulnerability. In Latin …

  7. Open Access 24-11-2022 | Amphotericin B | ReviewPaper

    Prevalence of visceral leishmaniasis among people with HIV: a systematic review and meta-analysis

    Leishmaniasis is a parasitic infection expressing different clinical phenotypes. Visceral leishmaniasis (VL) is considered an opportunistic infection among people with human immunodeficiency virus (HIV). The objective of this review was to …

  8. Open Access 01-12-2023 | Leishmania | OriginalPaper

    Visceral leishmaniasis–human immunodeficiency virus coinfection in a 52-year-old male in southwest Iran: a case report

    Leishmaniasis is a rare infectious disease observed in subtropical and tropical areas. This disease that demonstrates different clinical characteristics is caused by intracellular Leishmania protozoan [ 1 ]. One of the important countries facing …

  9. Open Access 03-11-2022 | Leishmania | OriginalPaper

    Updated diagnosis and graft involvement for visceral leishmaniasis in kidney transplant recipients: a case report and literature review

    Visceral leishmaniasis (VL) is an infectious disease caused by protozoa of the Leishmania donovani complex , and associated with considerable morbidity and mortality [ 1 ]. VL is also a known complication of solid organ transplantation (SOT) [ 2 ]; …

  10. Open Access 01-12-2022 | Leishmania | OriginalPaper

    Understanding the risk perception of visceral leishmaniasis exposure and the acceptability of sandfly protection measures among migrant workers in the lowlands of Northwest Ethiopia: a health belief model perspective

    Visceral leishmaniasis (VL), also known as kala-azar, is a vector-borne disease caused by the protozoan parasite Leishmania donovani (Order Kinetoplastida: Family Trypanosomatidae) and spread by phlebotomine sand flies (Order Diptera: Family: …

  11. Open Access 01-12-2021 | Kidney Injury | OriginalPaper

    Continuous hypergammaglobulinemia and proteinuria after the recovery of the visceral Leishmaniasis: a case report

    A 30-year-old male visited our outpatient clinic in March 2019, presented with irregular fever and newly-onset proteinuria. He was from Shanxi province in the northwestern part of China. His fever started in April 2018, with the highest body …

  12. Open Access 01-11-2021 | Leishmania | OriginalPaper

    Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients

    Over the past decades, substantial progress has been made in the treatment of visceral leishmaniasis (VL). Geographical differences in treatment efficacy have led to variable treatment recommendations for VL, with intramuscular paromomycin being …

  13. 01-12-2021 | Amphotericin B

    Efficacy and safety of single-dose liposomal amphotericin B in patients with visceral leishmaniasis in Bangladesh: a real-life experience

    Liposomal amphotericin B (LAmB) is the drug of choice in Bangladesh to eliminate the burden of visceral leishmaniasis, also known as kala-azar, a fatal protozoan parasitic disease if left untreated. We aimed to assess efficacy and safety of a …

  14. Open Access 01-12-2021 | Leishmania | OriginalPaper

    Performance of rapid rk39 tests for the diagnosis of visceral leishmaniasis in Ethiopia: a systematic review and meta-analysis

    Visceral leishmaniasis (VL), or kala-azar, is a neglected tropical parasitic disease caused by a group of intracellular hemoflagellate protozoans of the genus Leishmania and transmitted via the bite of infected female Phlebotomine sandflies [ 1 , 2 …]. Over 90% of the global VL burden is attributed to six less developed countries: Bangladesh, Brazil, India, Ethiopia, Sudan, and South Sudan [

  15. 01-12-2021 | Leishmania | OriginalPaper

    India’s performance in controlling Visceral Leishmaniasis as compared to Brazil over past three decades: findings from global burden of disease study

    Visceral leishmaniasis (VL) is a neglected tropical disease which contributes to the mortality and morbidity significantly in India and Brazil. This study was planned to compare the trends of incidence, prevalence, death and disability-adjusted …

  16. Open Access 01-12-2021 | Leishmania | OriginalPaper

    High levels of anti-Leishmania IgG3 and low CD4+ T cells count were associated with relapses in visceral leishmaniasis

    Visceral leishmaniasis (VL) is caused by Leishmania ( L .) infantum in Brazil, being transmitted to mammals by Lutzomyia longipalpis sand fly [ 1 ]. VL is endemic in more than 90 countries or territories, however, in 2017, few countries as Brazil …

  17. 01-01-2021 | Leishmania | Letter

    Visceral Leishmaniasis Associated with Hemophagocytic Lymphohistiocytosis

  18. Open Access 01-12-2021 | Leishmania | OriginalPaper

    Comparison of the clinical features and outcome of children with hemophagocytic lymphohistiocytosis (HLH) secondary to visceral leishmaniasis and primary HLH: a single-center study

    Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive inflammation and tissue destruction due to abnormal immune activation. The absence of normal downregulation by activated macrophages and lymphocytes is possibly the cause of hyper …

  19. Open Access 01-12-2021 | Anemia | OriginalPaper

    Hematological profiles of visceral leishmaniasis patients before and after treatment of anti-leishmanial drugs at University of Gondar Hospital; Leishmania Research and Treatment Center Northwest, Ethiopia

    Leishmaniasis is a category of tropical parasitic diseases caused by species of the genus Leishmania and transmitted by female phlebotomine sand flies. It's a zoonotic and anthroponotic disease, with humans and dogs being the most prevalent hosts …

  20. Open Access 01-12-2020 | Liver Function Test | OriginalPaper

    Characterization of visceral leishmaniasis outbreak, Marsabit County, Kenya, 2014

    Visceral leishmaniasis (VL), also known as Kala-azar, still remains a public health problem with both human and veterinary health significance. Globally, an estimated 500,000 cases of visceral leshmaniasis occurs annually and 90% of these cases …

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