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1186 search results for:

Systemic Mastocytosis 

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  1. 04-02-2024 | Mastocytosis | Online First

    Acute Myeloid Leukemia t (8;21) with Masked Systemic Mastocytosis

  2. Open Access 04-04-2023 | Systemic Mastocytosis | OriginalPaper

    Response and resistance to cladribine in patients with advanced systemic mastocytosis: a registry-based analysis

    We sought to evaluate the efficacy of the purine analogue cladribine in 79 patients with advanced systemic mastocytosis (AdvSM) using data from the ‘German Registry on Disorders of Eosinophils and Mast Cells (GREM)’. The overall response rate …

  3. 11-07-2023 | Systemic Mastocytosis | Letter

    Successful treatment of systemic mastocytosis with acute myeloid leukemia: a case report

    Treatment with avapritinib alongside idarubicin plus cytarabine led to a favorable outcome in a patient with systemic mastocytosis associated with acute myeloid leukemia.

  4. 09-06-2023 | Systemic Mastocytosis | OriginalPaper

    Assessment of Bone Microarchitecture in Patients with Systemic Mastocytosis and its Association with Clinical and Biochemical Parameters of the Disease

    Patients with systemic mastocytosis (SM) are at high risk of bone deterioration. However, the evaluation of bone microarchitecture in this disease remains unclear. We aimed to assess bone microarchitecture in patients with SM. This was a …

  5. Open Access 01-12-2023 | Mastocytosis | OriginalPaper

    Systemic mastocytosis mimicking blastic plasmacytoid dendritic cell neoplasm: a case report

    Mastocytosis, a unique and orphan disease, refers to a clonal and neoplastic proliferation of mast cells in one or more organ(s) [ 1 ]. The clinical manifestation of mastocytosis is heterogeneous, ranging from skin lesions that can spontaneously …

  6. 01-04-2021 | Systemic Mastocytosis | ReviewPaper

    Systemic mastocytosis revisited with an emphasis on skeletal manifestations

    Systemic mastocytosis (SM) is a rare form of mastocytosis that can affect various organ systems. Bone involvement is the most common and prominent imaging feature in patients with SM regardless of the subtype. Furthermore, bone involvement is a …

  7. Open Access 01-12-2023 | Midge | Erratum

    Correction : Health-related quality of life and health literacy in patients with systemic mastocytosis and mast cell activation syndrome

  8. Open Access 01-12-2023 | Mastocytosis | OriginalPaper

    Psychometric evaluation of the Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF©) and determination of a threshold score for moderate symptoms

    Systemic mastocytosis is a rare, clonal mast cell neoplasm driven by the KIT D816V mutation [ 1 ] that is characterized by uncontrolled proliferation and activation of mast cells, which leads to severe and unpredictable symptoms for patients with …

  9. Open Access 01-12-2020 | Systemic Mastocytosis | OriginalPaper

    An aggressive systemic mastocytosis preceded by ovarian dysgerminoma

    ASM is one of the advanced forms of systemic mastocytosis (SM) with a poor prognosis. In this disorder, clonal mast cells become abnormally accumulated in the skin, lymph nodes, liver, gastrointestinal tract and bone marrow (BM) where they are …

  10. Open Access 01-12-2023 | Omalizumab | OriginalPaper

    Successful treatment with Omalizumab of a child affected by Systemic Mastocytosis: clinical and biological implications

    Mastocytosis is a rare disease, with a prevalence of 1/10.000, characterized by clonal expansion and accumulation of mast cells in different tissues, mainly skin, and various organs, such as bone marrow, gastrointestinal tract, liver, spleen and …

  11. Open Access 20-09-2022 | Systemic Mastocytosis | Letter

    Towards personalized medicine with iPS cell technology: a case report of advanced systemic mastocytosis with associated eosinophilia

  12. 01-10-2021 | Tyrosine Kinase Inhibitors | ReviewPaper

    Avapritinib in the Treatment of Systemic Mastocytosis: an Update

    Mastocytosis, an uncommon hematologic malignancy, arises from the aberrant overproduction of neoplastic mast cells [ 1 ]. Patients with the disease manifest a heterogeneous set of clinical disorders including episodes of mast cell activation …

  13. Open Access 01-12-2022 | Mastocytosis | OriginalPaper

    Health-related quality of life and health literacy in patients with systemic mastocytosis and mast cell activation syndrome

  14. 01-04-2021 | Mastocytosis

    Systemic Mastocytosis: Response to the Efficacy of Cladribine(2-CdA) with Current Terminology and Approach

  15. Open Access 01-10-2020 | Mastocytosis | OriginalPaper

    The Efficacy of Cladribine (2-CdA) in Advanced Systemic Mastocytosis

    Systemic mastocytosis (SM) is a rare clonal disorder with multi-organ involvements and shortened life expectancy. To date, no curative treatment for SM exists. Cladribine (2-CdA) is a purine analogue showing activity against neoplastic mast cells …

  16. 01-10-2020 | Fluorescence in Situ Hybridization | Letter

    A Novel PDGFRβ Rearrangement in Systemic Mastocytosis with an Associated Haematologic Neoplasm

  17. 01-04-2020 | Primary Myelofibrosis | OriginalPaper

    Systemic Mastocytosis with Associated Primary Myelofibrosis

  18. 01-01-2020 | Acute Myeloid Leukemia | Letter

    Systemic mastocytosis associated with acute myeloid leukemia

  19. 01-02-2020 | Myelodysplastic Syndrome | Letter

    Systemic mastocytosis with associated BCRABL1-negative atypical chronic myeloid leukemia

  20. 01-06-2019 | Mastocytosis | OriginalPaper

    Higher prevalence of vertebral fractures in systemic mastocytosis, but not in cutaneous mastocytosis and idiopathic mast cell activation syndrome

    Mast cell disorders (MCDs) are rare conditions associated with mast cell activation, abnormal growth, and/or accumulation in different organs. Among MCDs, SM is known to frequently involve bone with secondary osteoporosis, fragility fractures, and …

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