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2297 search results for:

Sulfamethoxazole, Co-Trimethoprim 

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  1. Open Access 01-12-2023 | Toxoplasmosis | OriginalPaper

    Outcomes of trimethoprim/ sulfamethoxazole treatment for ocular toxoplasmosis in Congolese patients

    Ocular toxoplasmosis (OT) is the leading cause of infectious posterior uveitis in several geographical areas [ 1 , 2 ]. It is more common in South America, Central America, The Caribbean, and parts of tropical Africa compared to Europe and Northern …

  2. Open Access 01-12-2023 | Rituximab | OriginalPaper

    Trimethoprim-sulfamethoxazole prophylaxis during treatment of granulomatosis with polyangiitis with rituximab in the United States of America: a retrospective cohort study

    The anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV) are life-threatening systemic necrotizing small vessel vasculitides [ 1 ]. Rituximab (RTX) has increasingly become a first-line induction and maintenance treatment of …

  3. 14-07-2021 | Glucocorticoid | BriefCommunication

    Comparative effectiveness of trimethoprim-sulfamethoxazole versus atovaquone for the prophylaxis of pneumocystis pneumonia in patients with connective tissue diseases receiving prolonged high-dose glucocorticoids

    We compared the prophylactic effect of trimethoprim-sulfamethoxazole (TMP-SMX) with atovaquone for pneumocystis pneumonia (PCP) in patients with connective tissue diseases (CTDs) receiving high-dose glucocorticoids. Patients with CTDs aged ≥ 18 …

  4. 01-07-2021 | Antibiotic | OriginalPaper

    Trimethoprim-sulfamethoxazole as de-escalation in ventilator-associated pneumonia: a cohort study subanalysis

    β-lactam sparing strategies are strongly recommended to reduce the selection of extended spectrum β-lactamase (ESBL) and carbapenemase-producing bacteria [ 1 ]. Nevertheless, β-lactams are largely used for treatment of ventilator-associated …

  5. 01-12-2018 | OriginalPaper

    Safety of the concomitant use of methotrexate and a prophylactic dose of trimethoprim-sulfamethoxazole

    The objective of this study was to investigate risk factors for cytopenia when a prophylactic dose of trimethoprim-sulfamethoxazole (TMP-SMX) was co-administered with methotrexate (MTX). Patients who received MTX with or without a prophylactic …

  6. 01-08-2000 | OriginalPaper

    Pharmacokinetic Study of Azithromycin with Fluconazole and Cotrimoxazole (Trimethoprim-Sulfamethoxazole) in Healthy Volunteers

    Background: Azithromycin, fluconazole and cotrimoxazole (trimethoprim-sulfamethoxazole; TMP/SMX) are all agents that are utilised for the treatment and/or prophylaxis of opportunistic infections in patients with AIDS. Objective: To characterise …

  7. 01-07-2017 | OriginalPaper

    Frequent occurrence of trimethoprim-sulfamethoxazole hetero-resistant Staphylococcus aureus isolates in different African countries

    High rates of trimethoprim/sulfamethoxazole (SXT) resistance, a combination of two antifolate antibiotics trimethoprim (TMP) and sulfamethoxazole (SMZ), have been reported among Staphylococcus aureus isolates in Portuguese-speaking African …

  8. Open Access 01-12-2017 | OriginalPaper

    Optimal regimens of sulfamethoxazole-trimethoprim for chemoprophylaxis of Pneumocystis pneumonia in patients with systemic rheumatic diseases: results from a non-blinded, randomized controlled trial

    Pneumocystis pneumonia (PJP, also known as PCP) is a potentially life-threatening opportunistic infection caused by Pneumocystis jirovecii [ 1 , 2 ]. It has a predilection for immunocompromised patients. In the absence of chemical prophylaxis, the …

  9. Open Access 01-06-2016 | OriginalPaper

    Treatment of Pneumocystis pneumonia with intermediate-dose and step-down to low-dose trimethoprimsulfamethoxazole: lessons from an observational cohort study

    According to current guidelines and reviews, the recommended treatment of Pneumocystis jirovecii pneumonia (PCP) is high-dose trimethoprimsulfamethoxazole (TMP–SMX) in a dose of TMP 15–20 mg/kg/day and SMX 75–100 mg/kg/day for a duration of 2 or 3 …

  10. 01-10-1999 | OriginalPaper

    Trimethoprim-sulfamethoxazole resistance among urinary coliform isolates

    OBJECTIVE: A large majority of urinary tract infections are caused by coliform organisms. Trimethoprim-sulfamethoxazole (TMP-SMX) resistance among uropathogens is increasing in many areas. The objective of this study was to determine risk factors …

  11. Open Access 01-12-2016 | OriginalPaper

    TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial

  12. Open Access 01-05-2014 | Abstract

    Trimethoprim sulfamethoxazole drug resistance with co resistance to extended spectrum β-lactam antibiotics among bacterial isolates from HIV patients

    Trimethoprim-sulfamethoxazole (TMP-SMX) is a broad spectrum antimicrobial agent and also reduces the mortality among adults and children when used as prophylaxis against opportunistic infections in HIV infected patients. Drug resistant to TMP-SMX …

  13. 01-05-2008 | OriginalPaper

    Comparison of trimethoprimsulfamethoxazole and aerosolized pentamidine for primary prophylaxis of Pneumocystis jiroveci pneumonia in immunocompromised patients with connective tissue disease

    To evaluate the efficacy of primary prophylaxis for Pneumocystis jiroveci pneumonia (PCP) in patients with connective tissue disease (CTD) and immunosuppression, we compared trimethoprimsulfamethoxazole (TMP-SMZ) with aerosolized pentamidine.

  14. 01-07-1998 | OriginalPaper

    Drug-induced pneumonitis caused by sulfamethoxazole, trimethoprim during treatment of Pneumocystis carinii pneumonia in a patient with refractory ulcerative colitis

    We recently treated a patient with intractable ulcerative colitis complicated with Pneumocystis carinii pneumonia in whom sulfamethoxazole/trimethoprim caused pneumonitis. The pneumonitis was difficult to differentiate from worsening of the …

  15. 01-01-2013 | OriginalPaper

    Positivity for anti-RNP antibody is a risk factor for adverse effects caused by trimethoprimsulfamethoxazole, a prophylactic agent for P. jiroveci pneumonia, in patients with connective tissue diseases

    Pneumocystis pneumonia (PCP) is an uncommon but serious life-threatening complication caused by Pneumocystis jiroveci (formerly Pneumocystis carinii ) in immunocompromised hosts, such as patients with human immunodeficiency virus (HIV) and those …

  16. Open Access 04-04-2024 | Pneumonia | OriginalPaper

    A case of relapsing bronchopneumonia

    A patient with bronchopneumonia due to community-associated methicillin-resistant Staphylococcus aureus  had an unusual course, which involved repeated relapses and extended antibiotic treatment.

  17. Open Access 01-12-2024 | Pneumonia | OriginalPaper

    Ventilator-associated pneumonia related to extended-spectrum beta-lactamase producing Enterobacterales during severe acute respiratory syndrome coronavirus 2 infection: risk factors and prognosis

    Antimicrobial resistance is a leading global health issue. Lower respiratory tract infections alone accounted for more than 400,000 attributable deaths and 1.5 million associated deaths in 2019, worldwide [ 1 ]. Among critically ill patients …

  18. Open Access 01-12-2024 | Carbapenem Antibiotic | OriginalPaper

    Molecular epidemiology of carbapenem-resistant gram-negative bacilli in Ecuador

    The increasing number of multidrug-resistant organisms (MDROs) constitutes a major threat to health worldwide. MDROs are linked to increasing costs and mortality rates [ 1 ] and are an important challenge to clinicians due to the complicated choice …

  19. Open Access 01-12-2024 | Ciprofloxacin | ReviewPaper

    Increasing multidrug resistance in leech borne infections. Should we adjust antibiotic treatment regime in plastic surgery? A systematic review

    The use of leeches to treat soft tissue with congestion in plastic surgery gained over the last decades a sort of renaissance even with the parallel further development of micro- and supermicro surgery. Main indications for this since 2004 …

  20. Open Access 01-12-2024 | Linezolid | OriginalPaper

    Characterization of linezolid- and methicillin-resistant coagulase-negative staphylococci in a tertiary hospital in China

    Coagulase-negative staphylococci (CoNS) have become important pathogens in patients with health care-associated infections caused by indwelling medical devices or immunocompromised patients [ 1 , 2 ]. According to the monitoring data from the China …

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