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2752 search results for:

Sitagliptin 

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  1. Open Access 01-12-2024 | Semaglutide | OriginalPaper

    The long-term cost-effectiveness of once-weekly semaglutide versus sitagliptin for the treatment of type 2 diabetes in China

    There is a global epidemic of diabetes. China has the world’s largest number of diabetes population, with approximately 140.9 million people with a diagnosis, leading to associated deaths of 1.4 million and health expenditure of $165.3 billion in …

  2. Open Access 01-12-2024 | Sitagliptin | OriginalPaper

    Ipragliflozin and sitagliptin differentially affect lipid and apolipoprotein profiles in type 2 diabetes: the SUCRE study

    Diabetes is a major risk factor for the development of atherosclerosis and is associated with a 2- to 4-fold increased risk of cardiovascular disease [ 1 ]. Hyperglycemia, especially postprandial hyperglycemia, has been shown to cause …

  3. Open Access 18-01-2024 | Semaglutide | OriginalPaper

    Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Sitagliptin as Metformin Add-on in a Korean Population with Type 2 Diabetes

    The global prevalence of type 2 diabetes (T2D) more than doubled between 1990 and 2019, reaching approximately 437.9 million people. In addition, type 1 diabetes and T2D are directly responsible for approximately 1.5 million deaths worldwide per …

  4. Open Access 17-02-2024 | Sitagliptin | OriginalPaper

    A randomized, double-blind, active-controlled trial assessing the efficacy and safety of a fixed-dose combination (FDC) of MEtformin hydrochloride 1000 mg ER, SItagliptin phosphate 100 mg, and DApagliflozin propanediol 10 mg in Indian adults with type 2 diabetes: The MESIDA trial

    Two recent studies (VERIFY [NCT01528254] and GRADE [NCT01794143] having nearly similar (mean 5-year) follow-ups have now clearly suggested that the conventional approach of sequential addition of drugs in the treatment of type 2 diabetes (T2D) is …

  5. 01-05-2023 | Bullous Pemphigoid | News

    Sitagliptin

    Bullous pemphigoid : case report
  6. 24-06-2023 | Spironolactone | OriginalPaper

    Combination of spironolactone and sitagliptin improves clinical outcomes of outpatients with COVID-19: a prospective cohort study

    More than five million people have died from coronavirus disease 2019 (COVID-19) since the pandemic has started [ 1 ]. Patients with comorbidities, especially men and elderly, are at higher risk for death or hospitalization [ 2 ]. Although being …

  7. Open Access 16-12-2022 | Pharmacokinetics | OriginalPaper

    Bioequivalence Evaluation in Healthy Volunteers: New Generic Formulations of Sitagliptin and Sitagliptin–Metformin Fixed-Dose Combination Compared with the Originator Products

    The oral antidiabetic agent metformin is a member of the biguanide drug class that was originally described in 1922 and introduced into the pharmacologic management of type 2 diabetes (T2D) in 1958 [ 1 , 2 ]. Since then, initial pharmacologic …

  8. 07-11-2023 | Sitagliptin | OriginalPaper

    Efficacy and Safety of Switching from Sitagliptin to Ipragliflozin in Obese Japanese Patients with Type 2 Diabetes Mellitus: A Single-Arm Multicenter Interventional Study

    The goal of type 2 diabetes mellitus (T2DM) management is to achieve good glycemic control with glycosylated hemoglobin (HbA1c) serving as the main indicator [ 1 ]. Weight control and normalizing blood pressure and blood lipid parameters are also …

  9. 01-01-2023 | Bullous Pemphigoid | News

    Sitagliptin

    Bullous drug reaction: case report
  10. 01-10-2022 | Glimepiride | News

    Sitagliptin

    Collagenous colitis: case report
  11. 31-05-2023 | Metformin | OriginalPaper

    Fixed-Dose Combination of Dapagliflozin + Sitagliptin + Metformin in Patients with Type 2 Diabetes Poorly Controlled with Metformin: Phase 3, Randomized Comparison with Dual Combinations

    Type 2 diabetes (T2D) is a chronic and progressive condition associated with multiple micro- and macrovascular complications. Achieving glycemic control remains the main goal of treatment in an attempt to prevent these complications [ 1 ]. Current …

  12. Open Access 13-05-2023 | Sitagliptin | OriginalPaper

    Cost-Effectiveness of Semaglutide vs. Empagliflozin, Canagliflozin, and Sitagliptin for Treatment of Patients with Type 2 Diabetes in Denmark: A Decision-Analytic Modelling Study

    Type 2 diabetes (T2D) is a chronic and progressive disease associated with numerous risk factors, including obesity, and prognosis is related to lifestyle factors [ 1 ]. Numerous micro- [ 2 ] and macrovascular [ 3 ] complications of T2D are …

  13. 24-01-2023 | Sitagliptin | OriginalPaper

    A novel combination of sitagliptin and melatonin ameliorates T2D manifestations: studies on experimental diabetic models

    Lifestyle changes, principally, calorie-rich diet intake and nocturnality contribute to an increasing number of metabolic disorders, including obesity and Type 2 Diabetes (T2D) [ 1 ]. Disturbances in circadian rhythm are associated with metabolic …

  14. Open Access 01-12-2022 | Sitagliptin | OriginalPaper

    Regulation of Adropin by Sitagliptin monotherapy in participants with newly diagnosed type 2 Diabetes

    Adropin is a unique peptide hormone first reported in 2008. It contains 76 amino acids encoded by the Energy Homeostasis Associated (Enho) gene and is predominantly expressed in liver and brain [ 1 ]. Some animal studies have shown that adropin is …

  15. 01-03-2022 | Losartan | News

    Sitagliptin

    Lack of efficacy: case report
  16. Open Access 01-12-2022 | Sitagliptin | OriginalPaper

    Efficacy and safety of combination of empagliflozin and metformin with combination of sitagliptin and metformin during Ramadan: an observational study

    Ramadan is a lunar-based month lasting between 29 − 30 days. Fasting during the holy month of Ramadan constitutes one of the five main pillars of Islam and it is obligatory for all healthy adult Muslims to fast during Ramadan. The duration of …

  17. Open Access 01-12-2022 | Sitagliptin | OriginalPaper

    A budget impact analysis of substituting sitagliptin with liraglutide in type 2 diabetes from a private health insurance perspective in Egypt

    The upfront drug costs of adding liraglutide were offset by budget savings due to fewer CV-related complications and deaths avoided compared to the standard of care (modest budget impact). Sitagliptin resulted in a small budget impact but was …

  18. 01-10-2021 | Bullous Pemphigoid | News

    Sitagliptin/vildagliptin

    Pemphigoid nodularis: case report
  19. 01-09-2021 | Glibenclamide | News

    Sitagliptin

    Lack of efficacy: case report
  20. Open Access 01-05-2022 | Sitagliptin | OriginalPaper

    Long-Term Cost Effectiveness of Oral Semaglutide Versus Empagliflozin and Sitagliptin for the Treatment of Type 2 Diabetes in the Swedish Setting

    Type 2 diabetes (T2D) and its complications account for a substantial health and economic burden [ 1 ]. Costs are expected to substantially rise over time; the absolute global economic burden is expected to increase from US dollars (US$) 1.3 …

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