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Neurologic Therapy 

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  1. Open Access 01-12-2024 | Erratum

    Correction: Photobiomodulation combination therapy as a new insight in neurological disorders: a comprehensive systematic review

  2. 28-03-2024 | Stroke | News | Article

    Dual antiplatelet therapy reduces neurological deterioration in stroke

    All the patients were ineligible for intravenous thrombolysis or endovascular therapy.

  3. Open Access 01-12-2024 | Laser | OriginalPaper

    Photobiomodulation combination therapy as a new insight in neurological disorders: a comprehensive systematic review

    Preclinical and clinical studies have indicated that combining photobiomodulation (PBM) therapy with other therapeutic approaches may influence the treatment process in a variety of disorders. The purpose of this systematic review was to determine …

  4. Open Access 13-12-2023 | Anxiety | OriginalPaper

    Routine outcomes and evaluation of an 8-week outpatient multidisciplinary rehabilitative therapy program for functional neurological disorder

    Functional neurological disorder (FND) refers to genuinely experienced neurological symptoms that cause significant distress or disruption, without evidence of an underlying neurological, psychiatric or other medical explanation [ 1 , 2 ]. FND has …

  5. 11-03-2024 | Trisomy 21 | Online First

    Emerging Human Pluripotent Stem Cell-Based Human–Animal Brain Chimeras for Advancing Disease Modeling and Cell Therapy for Neurological Disorders

    Human pluripotent stem cell (hPSC) models provide unprecedented opportunities to study human neurological disorders by recapitulating human-specific disease mechanisms. In particular, hPSC-based human–animal brain chimeras enable the study of …

  6. Open Access 20-02-2024 | Biomarkers | OriginalPaper

    Early systemic insults following traumatic brain injury: association with biomarker profiles, therapy for intracranial hypertension, and neurological outcomes—an analysis of CENTER-TBI data

    Traumatic brain injury (TBI) is among the leading causes of mortality and long-term disability worldwide [ 1 , 2 ]. Clinical outcome is substantially related to the severity of primary injury and its impact on driving secondary injury mechanisms [ …

  7. Open Access 01-12-2023 | Stroke | OriginalPaper

    Early antithrombotic therapy in patients with postinterventional cerebral hyperdensity reduces early neurological deterioration after mechanical thrombectomy

    Acute ischemic stroke (AIS) is a prevalent disease with high morbidity, disability, and mortality rates all around the world [ 1 ]. Currently, endovascular thrombectomy (MT) and thrombolysis are the most efficient treatments for AIS. But nearly 20% …

  8. 06-01-2023 | Adenovirus | Online First

    Viral-mediated gene therapy in pediatric neurological disorders

    Childhood or adolescent-onset neurological disorders are prevalent in the pediatric clinic, ranking second only to respiratory disorders, and they are the primary cause of morbidity and mortality among chronic pediatric diseases [ 1 , 2 ]. The …

  9. Open Access 01-12-2022 | Anxiety | OriginalPaper

    Single session therapy in pediatric healthcare: the value of adopting a strengths-based approach for families living with neurological disorders

    Single session therapy (SST) has emerged as a promising therapeutic approach to address the psychosocial needs of pediatric patients and their families in a timely manner [ 1 ]. SST refers to a single session intervention between client and …

  10. Open Access 01-12-2023 | Niemann-Pick Disease | OriginalPaper

    Effects of miglustat therapy on neurological disorder and survival in early-infantile Niemann-Pick disease type C: a national French retrospective study

    Niemann-Pick disease type C (NP-C) is a rare autosomal recessive neurovisceral lipid storage disease characterized in a majority of cases by progressive neurological deterioration leading to premature death, and (hepato)splenomegaly; its estimated …

  11. 01-12-2021 | Psychotherapy | OriginalPaper

    Shared Individual Formulation Therapy (SIFT): an open-label trial of a new therapy accommodating patient heterogeneity in functional neurological disorder

    Functional Neurological Disorder (FND) is characterised by neurological symptoms inconsistent with, or in the absence of, recognised neuropathological causes. It is a significant cause of morbidity [ 1 ], with a widespread lack of specialist …

  12. Open Access 01-12-2023 | OriginalPaper

    Clustering trunk movements of children and adolescents with neurological gait disorders undergoing robot-assisted gait therapy: the functional ability determines if actuated pelvis movements are clinically useful

    The improvement of gait function is a frequent rehabilitation goal in pediatric rehabilitation [ 1 ]. Besides traditional physiotherapeutic interventions, robot-assisted gait therapies (RAGT) have become popular, including the Lokomat (Hocoma AG …

  13. 01-08-2021 | Infliximab | OriginalPaper

    Clinical course of central nervous system demyelinating neurological adverse events associated with anti-TNF therapy

    Previous studies have reported an association between anti-tumor necrosis factor alpha (anti-TNFα) treatment and central nervous system (CNS) events. We described eight patients presenting with demyelinating CNS events while on treatment with …

  14. Open Access 01-06-2021 | Stroke | ReviewPaper

    SARS-CoV-2 Infection: Symptoms of the Nervous System and Implications for Therapy in Neurological Disorders

    In this paper, the neurological aspects of COVID-19 are presented, which may be of significance for physicians. Knowledge about the neurological symptoms of COVID-19 infection should help physicians in diagnoses and in taking appropriate …

  15. Open Access 01-12-2023 | Multiple Sclerosis | ReviewPaper

    Combining robot-assisted therapy with virtual reality or using it alone? A systematic review on health-related quality of life in neurological patients

    Neurological diseases result in a broad spectrum of motor, functional, and cognitive impairments. Consequently, they represent the leading cause of disability and the second leading cause of death worldwide [ 1 ]. Contextually to populations …

  16. 01-12-2020 | Wilson's Disease | Original Research

    Combined sodium Dimercaptopropanesulfonate and zinc versus D-penicillamine as first-line therapy for neurological Wilson’s disease

    Wilson’s disease (WD) is a rare, genetic disorder in which the metabolism of copper is impaired. Mutations in a gene, called ATP7B, which encodes for a protein involved in copper-transportation, forms the genetic basis of WD. Thus, Copper …

  17. 01-12-2022 | Cranial MRI

    Neurological management and work-up of neurotoxicity associated with CAR T cell therapy

    Therapy with chimeric antigen receptor (CAR)-T cells directed against the B-cell surface marker CD19 is a new therapeutic approach for patients with malignant B-cell diseases [ 3 , 14 , 24 ]. In a retrospective study of 523 patients with refractory …

  18. 01-06-2020 | Metastasis | OriginalPaper

    Laser interstitial thermal therapy for in-field recurrence of brain metastasis after stereotactic radiosurgery: does treatment with LITT prevent a neurologic death?

    Brain metastasis (BM) affects up to one-third of adults with cancer and carries a historically bleak prognosis. Despite advances in stereotactic radiosurgery (SRS), rates of in-field recurrence (IFR) after SRS range from 10 to 25%. High rates of …

  19. 01-04-2022 | Magnetic Resonance Imaging | ReviewPaper

    Neurological side effects of radiation therapy

    Radiation therapy (RT) is one of the main treatments administered to patients with cancer. The development of technology has improved RT accuracy by allowing more precise delivery of high doses to the target volumes with reduced exposure of …

  20. 01-06-2022 | COVID-19 | ReviewPaper

    Neurological music therapy during the COVID-19 outbreak: updates and future challenges

    Over the past decades, pieces of evidences supported the therapeutic and rehabilitative role of music therapy (MT) in a wide spectrum of neurological disorders. Several music-based interventions (MBIs) aimed to enhance the sensory motor recovery …

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