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Landau-Kleffner Syndrome 

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  1. Open Access 01-12-2022 | Landau-Kleffner Syndrome | OriginalPaper

    A case of Landau-Kleffner syndrome with SLC26A4-related hearing impairment

    Landau-Kleffner syndrome (LKS) is characterized by acquired aphasia, electroencephalogram (EEG) abnormalities mainly in the temporoparietal region and infrequent seizures with good prognosis [ 1 , 2 ]. The onset of aphasia is usually subacute and …

  2. 01-11-2005 | OriginalPaper

    Management of Landau-Kleffner Syndrome

    Landau-Kleffner syndrome (LKS) is an acquired epileptic aphasia disorder in which children, usually 3–8 years of age who have developed age-appropriate speech, experience language regression with verbal auditory agnosia, abnormal epileptiform …

  3. 01-06-2001 | BriefCommunication

    Landau Kleffner Syndrome

    An eight-year-old male child presenting with history of generalized convulsions, gradual loss of speech and generalized EEG (electroencephalography) abnormalities was diagnosed as Landau Kleffner Syndrome. He initially developed generalized …

  4. 01-12-1999 | OriginalPaper

    Landau-Kleffner syndrome: Relation of clinical, EEG and Tc-99m-HMPAO brain SPECT findings and improvement in EEG after treatment

    Landau-Kleffner syndrome (LKS) is a rare childhood disorder characterized by acquired aphasia with seizures and electroencephalogram (EEG) abnormalities. Tc-99m-HMPAO SPECT was performed in three right handed children with LKS. A relative decrease …

  5. 01-10-2023 | Landau-Kleffner Syndrome | News

    Valproic-acid

    Cerebral pseudoatrophy: 3 case reports
  6. 01-02-2024 | OriginalPaper

    The 2022 International League Against Epilepsy Classification and Definition of Childhood Epilepsy Syndromes: An Update for Pediatricians

    The 2017 classification of the epilepsies of International League Against Epilepsy (ILAE) defined three diagnostic levels, including seizure type, epilepsy type and epilepsy syndrome. Epilepsy syndromes have been recognized as distinct …

  7. Open Access 25-09-2023 | ReviewPaper

    The Auditory Agnosias: a Short Review of Neurofunctional Evidence

    The term auditory agnosia denotes disorders of auditory input processing that follow damage to the central nervous system and cannot be explained by peripheral hearing loss. In extreme forms, these disorders result in cortical deafness—the patient …

  8. 25-10-2022 | Developmental Disorder | ReviewPaper

    Differential diagnosis between autism spectrum disorder and other developmental disorders with emphasis on the preschool period

    Neurodevelopmental disorders are a heterogeneous group of conditions characterized by delays or deviations in the acquisition of expected developmental milestones and behavioral changes. These disorders manifest early during the child’s …

  9. Open Access 01-12-2021 | Magnetic Resonance Imaging | OriginalPaper

    Clinical evaluation of neuroinflammation in child-onset focal epilepsy: a translocator protein PET study

    Epilepsy, a common chronic neurological disease, affects approximately 65 million people worldwide [ 1 ] and is the third contributor to the global burden in neurological disorders [ 2 ]. Etiologies, such as genetic structural abnormality …

  10. Open Access 01-12-2023 | Epilepsy | ReviewPaper

    Therapeutic efficacy of voltage-gated sodium channel inhibitors in epilepsy

    Epilepsy is a neurological disease characterized by excessive and abnormal hyper-synchrony of electrical discharges of the brain and a predisposition to generate epileptic seizures resulting in a broad spectrum of neurobiological insults, imposing …

  11. 12-07-2022 | Autism Spectrum Disorder | EditorialNotes

    Autism Spectrum Disorder and Epilepsy: Exploring the Missing Links

  12. 01-01-2021 | Epilepsy | ReviewPaper

    Sleep and Epilepsy: a Focused Review of Pathophysiology, Clinical Syndromes, Co-morbidities, and Therapy

    A healthy brain requires balancing of waking and sleeping states. The normal changes in waking and sleeping states result in neurophysiological conditions that either increase or decrease the tendency of seizures and interictal discharges to …

  13. 23-05-2023 | Vagus Nerve Stimulation | OriginalPaper

    Single-center long-term results of vagus nerve stimulation for pediatric epilepsy: a 10–17-year follow-up study

    According to an extensive meta-analysis, the cumulative incidence of drug-resistant epilepsy in children reaches 25%, surpassing that of adult and mixed-age patients [14.6%] [ 1 ]. In patients with drug-resistant epilepsy for whom resective surgery …

  14. 01-08-2021 | Antiepileptic Drugs | News

    Antiepileptic-drugs/immunoglobulins/prednisolone

    No drug effect: case report
  15. 01-01-2023 | Landau-Kleffner Syndrome | News

    Multiple drugs

    Lack of efficacy and rash: 4 case reports
  16. Open Access 01-12-2022 | Electroencephalography | OriginalPaper

    Short-term outcome of intravenous methylprednisolone pulse therapy versus oral prednisolone in patients with epileptic spasms

    An infantile spasm (IS) is an age-specific epileptic disorder of early infancy that typically presents with epileptic spasms occurring in clusters. The International League Against Epilepsy (ILAE) also recommends the term “IS syndrome” for …

  17. Open Access 01-12-2022 | Epilepsy | OriginalPaper

    Gene variations of glutamate metabolism pathway and epilepsy

    Epilepsy is a common chronic neurological disorder characterized by excessive neuronal firing in the brain leading to recurrent, episodic, and transient dysfunction of the central nervous system. Epilepsy affects nearly 10 million people in China …

  18. 01-02-2021 | Landau-Kleffner Syndrome | News

    Valproate/zonisamide

    Inefficacy: case report
  19. 05-08-2022 | Epilepsy | ReviewPaper

    Health Disparities in Pediatric Epilepsy: Methods and Lessons Learned

    Epilepsy affects 1% of youth and is associated with neurocognitive and psychosocial comorbidities, increased risk of mortality, and poor health-related outcomes. Health disparities in children and youth with epilepsy (CYE) have been understudied.

  20. Open Access 07-02-2023 | Antiepileptic Drugs | Letter

    Efficacy of perampanel as an adjunctive therapy in pediatric focal epilepsy

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