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23086 search results for:

Fracture Healing 

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  1. 15-05-2024 | Online First

    Comment on Byun et al.: The effect of teriparatide on fracture healing after atypical femoral fracture: a systematic review and meta-analysis

  2. Open Access 15-04-2024 | Fracture Healing | Online First

    Osteoimmunology of Fracture Healing

    Inflammation plays a critical role in robust bone fracture healing. Dysregulated inflammation, as seen in cases of advanced age, diabetes, obesity, and autoimmune disease, is often associated with non-union, delayed healing, and other …

  3. Open Access 01-12-2024 | Back Pain | OriginalPaper

    Capacitive biophysical stimulation improves the healing of vertebral fragility fractures: a prospective multicentre randomized controlled trial

    Vertebral fragility fractures (VFFs) are the most frequent type of osteoporotic fractures, with a reported annual incidence of 700,000 in the USA and 620,000 in Europe [ 1 ]. In Italy, VFFs have an estimated annual prevalence of 61,000 and an …

  4. Open Access 08-04-2024 | Fracture Healing | Online First

    Impact of osteoporosis and osteoporosis medications on fracture healing: a narrative review

    A recent fracture is a powerful risk factor for a subsequent fracture [ 1 ]. Therefore, it is imperative that osteoporosis treatment be initiated very soon after an incident fracture to decrease imminent fracture risk. However, a theoretical …

  5. 16-03-2024 | Online First

    A distinct “repair” role of regulatory T cells in fracture healing

    Regulatory T cells (Tregs) suppress immune responses and inflammation. Here, we described the distinct nonimmunological role of Tregs in fracture healing. The recruitment from the circulation pool, peripheral induction, and local expansion rapidly …

  6. Open Access 01-12-2024 | Fracture Healing | OriginalPaper

    Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats

    Fractures are among the most prevalent injuries affecting the musculoskeletal system, often due to bone injuries and various medical conditions [ 1 , 2 ]. The process of fracture healing is complex and influenced by numerous factors, including soft …

  7. 01-04-2024 | Root Fracture | OriginalPaper

    Healing and long-term prognosis of root-fractured permanent teeth: a retrospective longitudinal study

    Root fractures account for 1.2–7% of all traumatic dental injuries (TDI) in permanent teeth [ 1 ]. They result from a frontal impact over mature teeth, with complete root development, inducing shearing forces that are dissipated producing the …

  8. Open Access 01-12-2024 | Fracture Healing | ReviewPaper

    Monocyte alteration in elderly hip fracture healing: monocyte promising role in bone regeneration

    Individual aged with various change in cell and cellular microenvironments and the skeletal system undergoes physiological changes that affect the process of bone fracture healing. These changes are accompanied by alterations in regulating …

  9. Open Access 18-01-2024 | Fracture Healing | ReviewPaper

    Role of the Neurologic System in Fracture Healing: An Extensive Review

    This is one of many articles evaluating the utility of using AI to write scientific review articles on musculoskeletal topics [ 1 ]. The first draft of this review was written by humans and ChatGPT4.0 whereby humans selected literature references …

  10. Open Access 31-01-2024 | Fracture Healing | ReviewPaper

    Do Not Lose Your Nerve, Be Callus: Insights Into Neural Regulation of Fracture Healing

    This is one of many articles evaluating the utility of using AI to write scientific review articles on musculoskeletal topics [ 1 ]. The first draft of this review was written entirely by humans. Refer to this edition’s Comment paper for more …

  11. Open Access 13-01-2024 | Artificial Intelligence | ReviewPaper

    Using AI to Write a Review Article Examining the Role of the Nervous System on Skeletal Homeostasis and Fracture Healing

    Artificial intelligence (AI) has been growing rapidly and has garnered significant attention in recent months [ 1 ]. Its capabilities and applications are numerous, and it can perform tasks in seconds that would take most human users significantly …

  12. Open Access 01-12-2024 | Fracture Healing | ReviewPaper

    Modulation of fracture healing by senescence-associated secretory phenotype (SASP): a narrative review of the current literature

    The senescence-associated secretory phenotype (SASP) is a generic term for the secretion of cytokines, such as pro-inflammatory factors and proteases. It is a crucial feature of senescent cells. SASP factors induce tissue remodeling and immune …

  13. 04-01-2024 | OriginalPaper

    Great tuberosity fixation does not affect healing and clinical outcomes in RSA performed in proximal humeral fractures in elderly patients

    Proximal humeral fractures (PHF) represent almost 10% of all fractures (the third most common type of fracture) [ 1 , 2 ].

  14. 27-11-2023 | OriginalPaper

    Fracture related infection (FRI) of the upper extremity correlates with poor bone and soft tissue healing

    Fracture Related Infection (FRI) in upper extremity (UE) injuries are considered serious orthopedic complications following operative fixation. Fractures of the upper extremities are very common orthopedic injuries, yielding an annual incidence of …

  15. 01-12-2023 | Fracture Healing | OriginalPaper

    Investigating effects of locally applied boric acid on fracture healing with and without low-level laser therapy

    This study aimed to investigate the effects on fracture healing of locally applied boric acid (BA) with and without low-level laser therapy (LLLT). A unicortical femoral defect was surgically created on the anterolateral surface of proximal femur …

  16. 07-09-2023 | OriginalPaper

    Safety and Efficacy of Resveratrol in Healing of Maxillofacial Fractures: A Randomized Controlled Study

    Healing of fractured bone, following any insult, is an ever-evolving complex process [ 1 ]. Variable biological, mechanical, systemic and local regulatory factors like hormones and cytokines modulate to restore previous anatomic structure and …

  17. 04-08-2023 | Fracture Healing | OriginalPaper

    Adequate bone healing after supplementary fixation of periprosthetic total knee arthroplasty fractures using Luque cerclage wiring: a retrospective case series

    Cerclage wiring is a well-known reduction and supplemental fixation technique that is used during operative fixation of various long bone fractures [ 1 – 3 ]. As cerclage wiring requires adequate fracture exposure and dissection for insertion, and …

  18. Open Access 01-12-2023 | Ovariectomy | OriginalPaper

    Estrogen deficiency impedes fracture healing despite eliminating the excessive absorption of the posterior callus in a semi-fixed distal tibial fracture mouse model

    One of the most common injuries to the musculoskeletal system is bone fracture [ 1 ]. In the US alone, roughly 8 million people break a bone every year [ 2 ]. Fractures of the tibia, particularly the distal tibia, are at a higher risk of delayed …

  19. 25-09-2023 | Fracture Healing | OriginalPaper

    Monotropein Protects Mesenchymal Stem Cells from Lipopolysaccharide-Induced Impairments and Promotes Fracture Healing in an Ovariectomized Mouse Model

    Monotropein is one of the active ingredients in Morinda Officinalis, which has been used for the treatment in multiple bone and joint diseases. This study aimed to observe the in vitro effects of Monotropein on osteogenic differentiation of …

  20. Open Access 01-12-2023 | Hyperglycemia | OriginalPaper

    Expression of proinflammatory cytokines and proinsulin by bone marrow-derived cells for fracture healing in long-term diabetic mice

    The prevalence of diabetes mellitus (DM) is increasing globally due to lifestyle changes, urbanization, population growth, and aging demographics; the number of diabetic patients is expected to exceed 700 million by 2025 [ 1 , 2 ]. However, the …

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