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Eosinophilic Fasciitis 

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  1. Open Access 01-12-2024 | Eosinophilic Fasciitis | OriginalPaper

    Juvenile eosinophilic fasciitis: a single center case series

    Eosinophilic fasciitis (EF) is a rare fibrosing disease characterized by acute painful swelling and progressive induration [ 1 , 2 ]. Distal extremities are usually affected symmetrically or asymmetrically while the face and trunk are spared. Joint …

  2. 25-09-2023 | Ultrasound | ReviewPaper

    High-resolution musculoskeletal ultrasonography and elastography for eosinophilic fasciitis diagnosis and follow-up: a case-based review

    Eosinophilic fasciitis (EF) remains a rare condition without precise diagnostic criteria due to common symptoms with other autoimmune diseases requiring broad differential diagnosis. This paper describes the use of high-resolution musculoskeletal …

  3. 19-09-2022 | Eosinophilic Fasciitis | EditorialNotes

    Dystrophic calcinosis in eosinophilic fasciitis

    A 68-year-old female presented for evaluation of “cord-like thickening” on bilateral lateral legs, which had an onset several months ago, non-progressive, and otherwise asymptomatic. On examination, there was hard, linear, and non-tender …

  4. 30-07-2022 | Systemic Sclerosis | EditorialNotes

    The groove sign in eosinophilic fasciitis

    A 56-year-old previously healthy man presented with a 1-month history of swelling of the extremities, with a 7-kg weight gain. Physical examination revealed bilateral pitting edema in the forearms and legs, with erythema and skin induration. On …

  5. 01-10-2021 | Azathioprine

    Rituximab for refractory eosinophilic fasciitis: a case series with long-term follow-up and literature review

    EF is a rare connective tissue disease characterized by thickening of the deep fascia of the muscles. The first description was done by Shulman on 1974 [ 1 ]. The diagnosis is definitively established by a full thickness biopsy of the affected skin …

  6. 01-08-2021 | Intrauterine Growth Restriction | ReviewPaper

    Eosinophilic fasciitis in a pregnant woman with corticosteroid dependence and good response to infliximab

    Eosinophilic fasciitis (EF) is characterized by symmetrical thickening of subcutaneous muscular fascia, causing skin induration with wrinkles and prominent hair follicles: the classic peau d’orange. Eosinophilia is a characteristic—albeit not …

  7. Open Access 01-12-2021 | Multiple Myeloma | OriginalPaper

    Eosinophilic fasciitis (Shulman syndrome), a rare entity and diagnostic challenge, as a manifestation of severe chronic graft-versus-host disease: a case report

    Shulman’s disease, or eosinophilic fasciitis (EF), is a rare autoimmune disease characterized by sclerodermic skin lesions with progressive induration and thickening of the soft tissues [ 1 – 3 ]. Other clinical manifestations can be fever …

  8. 01-06-2021 | Eosinophilia | BriefCommunication

    18F-FDG PET/CT and MRI findings of Shulman syndrome also known as eosinophilic fasciitis

  9. 01-06-2021 | Systemic Lupus Erythematosus | ReviewPaper

    A case of eosinophilic fasciitis without skin manifestations: a case report in a patient with lupus and literature review

    Eosinophilic fasciitis (EF) is a rare connective tissue disease that causes inflammation and fibrosis of the fascia, inducing pain and motor dysfunction. Characteristic skin manifestations, such as edema, erythema, induration, peau d’orange …

  10. Open Access 01-12-2020 | Melanoma | OriginalPaper

    Immune Checkpoint Inhibitor-Associated Scleroderma-Like Syndrome: A Report of a Pembrolizumab-Induced “Eosinophilic Fasciitis-Like” Case and a Review of the Literature

    Immune checkpoint inhibitors are a promising new therapeutic strategy in oncology that aims to eliminate cancer cells by enhancing patients' immune response against tumor antigens. Despite their beneficial effects, immune checkpoint inhibitors are …

  11. 01-05-2020 | Tocilizumab | ReviewPaper

    The use of tocilizumab in the treatment of refractory eosinophilic fasciitis: a case-based review

    Eosinophilic fasciitis (EF) is a rare disorder involving chronic inflammation of the fascia and connective tissue of unknown aetiology and poorly understood pathogenesis. We present the case of a 60-year-old man diagnosed with eosinophilic

  12. 01-10-2018 | OriginalPaper

    Ultrasonographic images of the hand in a case with early eosinophilic fasciitis

    Eosinophilic fasciitis (EF), a rare rheumatic disease, usually affects the limbs symmetrically and generally spares the hands and feet. Cases of unilateral hand involvement are rarely reported. Here, we report such a rare case. Ultrasonography …

  13. 01-03-2018 | ReviewPaper

    Eosinophilic fasciitis during pregnancy: case report and review of literature

    The authors describe the case of a 23-year-old woman who was referred to the rheumatologist due to symmetrical and progressive stiffness, induration, and swelling of arms and thighs at the 12th week of her first gestation. The characteristic …

  14. 01-12-2017 | ReviewPaper

    Eosinophilic Fasciitis: an Updated Review on Diagnosis and Treatment

    Eosinophilic fasciitis (EF) is a rare fibrosing disorder first described by Shulman in 1974 [ 1 ], typified by erythema, edema, and induration of the bilateral extremities. Characteristic findings include a pseudocellulite or peau d’orange …

  15. Open Access 01-08-2017 | ReviewPaper

    Morphea and Eosinophilic Fasciitis: An Update

    Morphea, also known as localized scleroderma, encompasses a group of idiopathic sclerotic skin diseases. The spectrum ranges from relatively mild phenotypes, which generally cause few problems besides local discomfort and visible disfigurement, to …

  16. 01-10-2015 | BriefCommunication

    Finger stiffness or edema as presenting symptoms of eosinophilic fasciitis

    To investigate the clinical features and finger symptoms of eosinophilic fasciitis (EF), we reviewed five patients with EF. The chief complaint was pain, edema and/or stiffness of the extremities. The distal extremities were affected in all …

  17. Open Access 01-12-2015 | Abstract

    Juvenile eosinophilic fasciitis: report of three cases with a review of the literature

    Eosinophilic fasciitis (EF), also called Shulman's syndrome or fasciitis-panniculitis syndrome, is an uncommon scleroderma-like disorder of unknown etiology, characterized by induration and thickening of skin and soft tissue, usually associated …

  18. 01-10-2002 | OriginalPaper

    Eosinophilic fasciitis leading to painless contractures

    We report on an 11-year-old girl who developed multiple joint contractures over a period of 3 months. The disease presented with progressive involvement of the fingers, elbows, shoulders, knees and feet and was not accompanied by other symptoms.

  19. 01-09-2003 | OriginalPaper

    Paraneoplastic eosinophilic fasciitis: a case report

    A 60-year-old white woman with polycythemia rubra vera post splenectomy in November 2001 was found to have peripheral white blood cell counts increasing over 3 months. Cytogenetics revealed trisomy of chromosomes 8 and 9, and bone marrow biopsy …

  20. 01-12-2005 | Report

    Eosinophilic fasciitis successfully treated with cyclosporine

    We report on a 45-year-old female who developed eosinophilic fasciitis, characterized by scleroderma-like skin indurations, predominantly on the extremities and chest, with joint contractures and intermittent blood eosinophilia. Histologic …

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