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2026 search results for:

Craniosynostosis 

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  1. Open Access 22-04-2024 | Craniosynostosis | Online First

    Machine learning applications in craniosynostosis diagnosis and treatment prediction: a systematic review

    Craniosynostosis refers to the premature fusion of one or more of the fibrous cranial sutures connecting the bones of the skull. Machine learning (ML) is an emerging technology and its application to craniosynostosis detection and management is …

  2. 22-04-2024 | Craniosynostosis | Online First

    Management of an older Marshall-Smith syndrome patient: a review of literature of MSS and craniosynostosis

    Marshall-Smith Syndrome (MSS) is a rare progressive developmental disorder that severely impairs a patient’s intellectual development and physical health. The only known cause for MSS is a mutation in the nuclear factor 1 X (NFIX) gene. This …

  3. 31-01-2024 | Craniosynostosis | OriginalPaper

    Evaluation of neurocognitive and social developments after craniosynostosis surgery

    Craniosynostosis refers to the premature closure of one or more skull sutures before the normal developmental period, resulting in skull deformities [ 1 ]. Non-syndromic craniosynostosis (NSC), the focus of this study, refers to skull deformities …

  4. 08-03-2024 | Intracranial Hypertension | Letter

    Non-invasive intracranial pressure analysis in craniosynostosis: an intriguing insight

  5. 05-04-2024 | Craniosynostosis | Online First

    Sports participation after craniosynostosis repair: the critical role of post-operative guidance in parental decision-making

    While surgical correction of craniosynostosis is considered safe, the literature reveals a notable gap in understanding the factors influencing long-term lifestyle decisions made by patients and their families post-operatively [ 1 ]. Among these …

  6. 01-12-2024 | Craniosynostosis | OriginalPaper

    Skeletal expansion via craniofacial distraction osteogenesis technique in syndromic craniosynostosis: impact on ophthalmic parameters

    Craniosynostosis is the early closure of one or more cranial sutures. The incidence of craniosynostosis is 1:2000 to 2500 live births worldwide and approximately 25% of patients with craniosynostosis are syndromic and involve more than one cranial …

  7. 04-01-2024 | Craniosynostosis | OriginalPaper

    A diffusion tensor imaging comparison of white matter development in nonsyndromic craniosynostosis to neurotypical infants

    Nonsyndromic craniosynostosis (NSC) has an incidence of 0.4 to 1 in 1000 live births [ 1 ] and is defined at our institution as any single-suture craniosynostosis in the absence of additional anomalies of the face, trunk, or limbs. NSC is …

  8. 07-02-2024 | Online First

    Secondary metopic craniosynostosis after posterior cranial decompression in cloverleaf skull deformity

    Cloverleaf skull deformity or Kleeblattschadel syndrome is a severe condition where multiple cranial sutures are absent and prematurely fused, leading to a trilobate head shape. The remaining open sutures or fontanelles compensate for rapid brain …

  9. Open Access 01-12-2024 | Craniosynostosis | OriginalPaper

    Periostin/Bone Morphogenetic Protein 1 axis axis regulates proliferation and osteogenic differentiation of sutured mesenchymal stem cells and affects coronal suture closure in the TWIST1+/− mouse model of craniosynostosis

    Craniosynostosis is a common congenital skull defect characterized by premature closure of the coronal suture [ 1 ]. This disease causes abnormal growth and development of the skull, which can lead to a series of serious problems such as abnormal …

  10. Open Access 02-11-2023 | Craniosynostosis | OriginalPaper

    Patient-reported outcome measures more than fifteen years after treatment of sagittal or metopic craniosynostosis: a prospective cohort study

    Craniosynostosis is a congenital condition that involves premature and pathological fusion of one or multiple cranial sutures [ 1 ]. The incidence of craniosynostosis is around 1 in 2500 live births [ 2 ]. Craniosynostosis mainly presents as an …

  11. 15-11-2023 | Craniosynostosis | ReviewPaper

    Posterior cranial vault distraction in children with syndromic craniosynostosis: the era of biodegradable materials—a comprehensive review of the literature and proposed novel global application

    Distraction osteogenesis is utilized to increase intracranial volume in the treatment of restrictive pathologies, most commonly syndromic synostosis. Children too young for open calvarial vault expansion or other systemic or local …

  12. Open Access 05-01-2024 | Polysomnography | Online First

    The effect of continuous positive airway pressure on obstructive sleep apnea in children with syndromic craniosynostosis

    Pediatric obstructive sleep apnea (OSA) is a common condition that affects 2% to 4% of the population [ 1 , 2 ]. Recurrent episodes of upper airway obstruction during sleep lead to oxygen desaturation, hypercapnia, paradoxical thoracoabdominal …

  13. 06-09-2023 | Craniosynostosis | OriginalPaper

    Atypical sagittal suture craniosynostosis: pathological considerations for early closure of the anterior part of the sagittal suture

    Sagittal suture synostosis is one of the most common craniosynostoses and is often diagnosed by characteristic narrow and long skull shape, scaphocephaly. However, some patients with sagittal suture synostosis do not present with typical …

  14. Open Access 18-07-2023 | Craniosynostosis | OriginalPaper

    Frequency and predictors of concurrent complications in multi-suture release for syndromic craniosynostosis

    Craniosynostosis occurs in nearly 1 in 2000–2500 live births [ 1 , 2 ]. Because craniosynostosis is associated with learning impairment, headaches, and potential visual loss and blindness [ 3 ], cranial vault remodeling (CVR) is performed to expand …

  15. 26-07-2023 | Craniosynostosis | OriginalPaper

    Analysis of intracranial pressure waveform using a non-invasive method in individuals with craniosynostosis

    Patients with craniosynostosis may present symptoms and signs resulting from changes in cranial compliance (CC). Compliance is a physical concept that relates to the container and its contents. Therefore, CC is the relationship between …

  16. 01-12-2023 | Craniosynostosis | OriginalPaper

    Outcomes of the early endoscopic-assisted suturectomy for treatment of multisuture craniosynostosis

    To present the outcomes and adverse events associated with the endoscopic-assisted, minimally invasive suturectomy in patients with multisuture synostosis. This retrospective cohort study included children < 65 days of age who underwent …

  17. 08-07-2023 | Craniosynostosis | OriginalPaper

    Craniosynostosis in primary metabolic bone disorders: a single-institution experience

    Craniosynostosis is defined a premature close of one or more skull sutures, resulting in abnormal head shape as well as restriction in brain growth and development [ 1 ]. This disorder can occur due to primary mutation in genes responsible for …

  18. Open Access 27-05-2023 | Craniosynostosis | OriginalPaper

    Radiomorphologic profiles of nonsyndromic sagittal craniosynostosis

    Despite several clinical and scientific approaches, nonsyndromic sagittal craniosynostosis (NSC) still remains a heterogeneous entity, investigated from various perspectives. Current research highlights not only its morphology, but also genetic …

  19. Open Access 21-07-2023 | Craniosynostosis | ReviewPaper

    Cosmetic satisfaction and patient-reported outcomes following surgical treatment of single-suture craniosynostosis: a systematic review

    Craniosynostosis is a condition characterized by premature fusion of one or more cranial sutures [ 1 – 3 ]. The incidence of craniosynostosis is around 1 in 2500 live births [ 4 ]. Approximately 8% of patients suffer from a syndromic or familial …

  20. 16-09-2023 | Pediatric Neurosurgery | Erratum

    Correction: Technical evolution of pediatric neurosurgery: craniosynostosis from 1972 to 2023 and beyond

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