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Cholesteatoma 

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  1. 24-04-2024 | Cholesteatoma | Online First

    Metagenome Analysis of Cholesteatoma-associated Bacteria: A Pilot Study

    Chronic otitis media (COM) is one of the chief causes of hearing impairment in children and young adults in developing countries including India [ 1 ]. COM is primarily of two types- mucosal and squamosal. Squamosal COM occurs due to epithelium …

  2. 26-04-2024 | Cholesteatoma | Online First

    Pediatric Cholesteatoma: An Overview of Presentation, Surgical Strategy and Outcomes of an Individualized Approach

    Pediatric cholesteatomas (PC) have multifactorial aetiology, spread aggressively and there are high chances of residual/ recurrent disease after treatment. The surgical technique to manage this entity has been debatable. This study was done to (i) …

  3. 23-02-2024 | Cholesteatoma | ReviewPaper

    Congenital cholesteatoma: what radiologists need to know

    Congenital cholesteatoma is a rare, non-neoplastic lesion that causes conductive hearing loss in children. It is underrecognized and often diagnosed only when there is an established hearing deficit. In the pediatric population, hearing deficiency …

  4. Open Access 16-01-2024 | Cholesteatoma | OriginalPaper

    Combined microscope–endoscopy resection of petrous bone cholesteatoma with temporary facial nerve transposition versus nontransposition

    Petrous bone cholesteatoma refers to cholesteatoma medial to the otic capsule. It has slow growth, a complex location in the skull base, and proximity to important neurovascular structures, which make its diagnosis and treatment very challenging [ …

  5. Open Access 22-03-2024 | Cholesteatoma | Online First

    Occurrence of mucosa-affecting diseases of the upper airways in middle ear cholesteatoma patients: a nationwide case–control study

    The mucosa lining the tympanic cavity is continuous with the Eustachian tube, the nasopharynx, and the mastoid [ 1 ]. An association between chronic rhinosinusitis (CRS) and chronic otitis media (COM), a chronic inflammation of the middle ear, has …

  6. 18-10-2023 | Cholesteatoma | OriginalPaper

    Endoscopic Assessment of Cholesteatoma Following Microscope Assisted Tympano: Mastoidectomy

    Study design: a cross section descriptive study

    Cholesteatoma has proven to be a formidable enemy as it can erode bone, destroy ossicles, and invade inner ear or facial canal causing facial paralysis, vertigo and sensorineural hearing loss and intracranial complications. Its eradication remains …

  7. Open Access 13-02-2024 | Cholesteatoma | Online First

    Predicting residual cholesteatoma with the Potsic staging system still lacks evidence: a systematic review and meta-analysis

    The most widely used staging system for congenital cholesteatoma is the one that was described by Potsic and colleagues in 2002 [ 1 ], which is based on the extension of the disease behind an intact tympanic membrane. A cholesteatoma limited to a …

  8. 30-09-2023 | Cholesteatoma | OriginalPaper

    Acquired cholesteatoma after cochlear implants: case series and literature review

    Cochlear implantation is considered a safe and life-changing procedure with relatively low complication rates [ 1 ]. According to a review, cholesteatoma complicates 0.5% of cochlear implants [ 2 ]. Although a rare and delayed complication, a …

  9. Open Access 05-08-2023 | Cholesteatoma | OriginalPaper

    Reconstructive ossiculoplasty options in primary cholesteatoma surgeries with an intact stapes

    Primary acquired cholesteatomas in children and adults might result in conductive hearing loss due to ossicular chain involvement. Erosion of the long process of the incus is most frequently observed [ 1 ]. The integrity and mobility of the stapes …

  10. Open Access 01-12-2023 | Cholesteatoma | OriginalPaper

    Intratympanic membrane cholesteatoma after traumatic tympanic membrane perforation: a case report

    Congenital cholesteatoma in the middle ear is commonly observed in children [ 1 ]. However, cholesteatoma in the tympanic membrane is rare [ 2 ]. The condition presents as an asymptomatic, white, round mass on the tympanic membrane, and is usually …

  11. Open Access 24-10-2023 | Cholesteatoma | OriginalPaper

    Cholesteatoma Severely Impacts the Integrity and Bone Material Quality of the Incus

    Cholesteatoma can lead to progressive destruction of the auditory ossicles along with conductive hearing loss but precise data on the microstructural, cellular, and compositional aspects of affected ossicles are not available. Here, we obtained …

  12. 22-09-2023 | Cholesteatoma | OriginalPaper

    Monozygotic twins and cholesteatomas: nature or nuture?

    Cholesteatomas are tumours of keratinising squamous epithelium within the middle ear—they can be classified into congenital and acquired forms [ 1 ]. Although benign, they can cause significant morbidity including hearing loss, infection …

  13. Open Access 03-08-2023 | Cholesteatoma | OriginalPaper

    Temporal bone CT-based anatomical parameters associated with the development of cholesteatoma

    Cholesteatoma is caused by disorders of the middle ear ventilation that trigger a progressive series of events (formation of retraction pockets, entry of keratinocytes into the tympanic cavity, etc.), which are responsible for its formation [ 1 – 4 …]. This ventilation can be compromised when three conditions occur:

  14. 21-06-2023 | Cholesteatoma | OriginalPaper

    Outcomes and Review in Surgery of Lateral Semicircular Canal Dehiscence in Cholesteatomatous Otitis Media: A Case Series

    Labyrinthine fistula is one of the most frequent complications of cholesteatoma otitis. We report two cases where a canal wall down mastoidectomy is made due to the characteristics of the cholesteatoma, achieving good outcomes in relation to bone …

  15. Open Access 23-05-2023 | Cholesteatoma | OriginalPaper

    EAONO/JOS classification for acquired cholesteatoma: evaluating the impact of the number of affected sites on treatment and outcomes

    The Japanese Otological Society (JOS) published in 2008 a classification system for middle ear cholesteatoma [ 1 ], which was reviewed in 2010 [ 2 ] and 2015 [ 3 ]. The European Academy of Otology and Neurotology (EAONO) presented its own system in …

  16. 07-05-2023 | Magnetic Resonance Imaging | OriginalPaper

    PROPELLER diffusion weighted imaging for diagnosis of cholesteatoma in comparison with surgical and histopathological results: emphasis on false positivity and false negativity

    Cholesteatoma is a common destructive lesion of the middle ear and mastoid, consisting of keratinized squamous epithelium [ 1 ]. Cholesteatomas are categorized into two types; the acquired cholesteatomas are more commonly encountered and associated …

  17. Open Access 01-12-2021 | Magnetic Resonance Imaging | OriginalPaper

    The pterional approach for the surgical resection of an orbital cholesteatoma: a case report

    Different inflammatory, vascular, cystic, and neoplastic lesions have their origin at the orbit. Among these, mesenchymal and lymphoproliferative tumors account for most cases of orbital lesions, although other neurogenic, lacrimal, and metastatic …

  18. 01-08-2021 | Cholesteatoma | OriginalPaper

    Super-enhancer Acquisition Drives FOXC2 Expression in Middle Ear Cholesteatoma

    Distinct histone modifications regulate gene expression in certain diseases, but little is known about histone epigenetics in middle ear cholesteatoma. It is known that histone acetylation destabilizes the nucleosome and chromatin structure and …

  19. 26-01-2023 | Endoscopy | OriginalPaper

    Efficiency of intraoperative endoscopic inspection in reducing residuals in canal-wall-up surgery for pediatric cholesteatoma involving the mastoid

    Surgical management of pediatric cholesteatoma is challenging because of its characteristics of aggressive growth in the well-pneumatized middle ear and high possibilities of residual and recurrence [ 1 – 4 ]. In recent years, endoscopy has been …

  20. 13-02-2023 | Computed Tomography | OriginalPaper

    Coexistence of Primary External Auditory Canal Cholesteatoma and Tympanomastoid Paraganglioma: A Diagnostic Dilemma

    Synchronous presentation of cholesteatoma and tympanomastoid paraganglioma is extremely rare. Due to the overlapping clinical features, the clinical diagnosis of coexistence is difficult. Only two cases of tympanomastoid paraganglioma coexisting …

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