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5329 search results for:

Anticholinergic Syndrome 

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  1. Open Access 01-11-2019 | Overactive Bladder | OriginalPaper

    Efficacy and safety of non-ablative vaginal erbium:YAG laser treatment as a novel surgical treatment for overactive bladder syndrome: comparison with anticholinergics and β3-adrenoceptor agonists

    Overactive bladder syndrome (OAB), a syndrome characterized by the chief complaint of urinary urgency, is often accompanied by frequent urination, nocturia, and occasional urinary incontinence [ 1 , 2 ]. This condition significantly reduces quality …

  2. 01-12-2011 | Letter

    Possible central anticholinergic syndrome following transdermal scopolamine in an ambulatory surgery patient

  3. Open Access 19-03-2024 | Movement Disorder | Review

    An Evidence-Based Update on Anticholinergic Use for Drug-Induced Movement Disorders

    Anticholinergic medications can be effective in treating drug-induced parkinsonism and dystonia, but they are not recommended for the treatment of tardive dyskinesia, akathisia, or neuroleptic malignant syndrome.

  4. Open Access 01-12-2024 | Antidepressant Drugs | OriginalPaper

    Deprescribing of antidepressants: development of indicators of high-risk and overprescribing using the RAND/UCLA Appropriateness Method

    Antidepressants are first-line medications for many psychiatric disorders (including depression, anxiety disorders, and obsessive–compulsive disorder) and have proven to have substantial benefits particularly in patients with moderate to severe …

  5. Open Access 01-12-2024 | OriginalPaper

    Development and validation of a new drug-focused predictive risk score for postoperative delirium in orthopaedic and trauma surgery patients

    Delirium is defined as an acute change in attention, awareness, and cognition [ 1 ]. It usually develops rapidly with a fluctuating course [ 1 ]. In elderly, hospitalized patients, it represents a severe complication with a prevalence ranging from …

  6. Open Access 13-05-2024 | Dementia | Online First

    Predictors of Adverse Drug Reaction-Related Hospitalisations Among People with Dementia: A Retrospective Case-Control Study

    An adverse drug reaction (ADR) is defined by the World Health Organization (WHO) as “any response to a drug which is noxious and unintended, and which occurs at doses normally used in man for prophylaxis, diagnosis or therapy of disease, or for …

  7. 03-05-2024 | Overactive Bladder | Online First

    Anticholinergic Burden in Patients Treated for Overactive Bladder: Second-Line Therapy with Tibial Nerve Stimulation as a Solution

    Overactive bladder (OAB) is a highly prevalent condition with significant associated comorbidities. Current management guidelines suggest the utilization of anticholinergic medication as a second line after nonpharmacological treatment. Tibial …

  8. 11-03-2024 | Alzheimer's Disease | OriginalPaper

    Cumulative Anticholinergic Burden and its Predictors among Older Adults with Alzheimer’s Disease Initiating Cholinesterase Inhibitors

    Alzheimer’s disease (AD), a progressive neurologic disorder, accounts for 60–80% of dementia cases [ 1 ]. It is a multifactorial disease characterized by loss of cholinergic neurons in the brain, amyloid-β accumulation, and decreased levels of the …

  9. Open Access 01-12-2024 | Dementia | OriginalPaper

    Potentially inappropriate prescribing for people with dementia in ambulatory care: a cross-sectional observational study

    Dementia is a progressive syndrome caused by underlying neurodegenerative processes and characterised by a decline from a previously attained cognitive level that affects memory, thinking, behaviour and activities of daily living [ 1 ]. The …

  10. 01-12-2024 | Neurogenic Bladder | OriginalPaper

    Long-term urodynamic findings following colo-, gastro- and ileocystoplasty

    Upper urinary tract deterioration and urinary incontinence are the two major indications for bladder augmentation when bladder capacity and compliance are significantly decreased.

  11. Open Access 01-12-2024 | Urinary Incontinence | OriginalPaper

    Prevalence of urinary incontinence and associated factors in nursing homes: a multicentre cross-sectional study

    Urinary incontinence (UI) is a common geriatric syndrome affecting bladder health; it affects more than half nursing home (NH) residents, leading to health consequences such as pressure ulcers, urinary tract infections, falls or worsened quality …

  12. Open Access 08-04-2024 | Parkinson's Disease | OriginalPaper

    On the Optimal Diagnosis and the Evolving Role of Pimavanserin in Parkinson’s Disease Psychosis

    Parkinson’s disease (PD) is associated with the development of psychosis (PDP), including hallucinations and delusions, in more than half of the patient population. Optimal PD management must therefore involve considerations about both motor and …

  13. Open Access 26-04-2024 | Online First

    Persistent negative symptoms in young people at clinical high risk of psychosis treated with an Italian early intervention program: a longitudinal study

    Negative symptoms in CHR-P people are generally not responsive to treatments and commonly related to poorer functional outcome. However, less research attention has been dedicated to Persistent Negative Symptoms (PNS), defined as clinically stable …

  14. Open Access 01-12-2024 | Overactive Bladder | ReviewPaper

    Medicinal plants and natural products for treating overactive bladder

    Lower urinary tract symptoms (LUTS) impact over 50% of the global adult population [ 82 ]. These symptoms emcompass storage, voiding, and post-micturition symptoms. Notably, overactive bladder (OAB) syndrome is classified as a specific subset …

  15. 09-01-2024 | Abstract

    51st ESCP symposium on clinical pharmacy 31 October–02 November 2023, Aberdeen, Scotland

    Innovations in clinical pharmacy practice, education and research
  16. 18-05-2024 | Online First

    HDAC inhibitors as a potential therapy for chemotherapy-induced neuropathic pain

    Cancer, a chronic disease characterized by uncontrolled cell development, kills millions of people globally. The WHO reported over 10 million cancer deaths in 2020. Anticancer medications destroy healthy and malignant cells. Cancer treatment …

  17. Open Access 01-12-2024 | Overactive Bladder | OriginalPaper

    The impact of pharmacotherapy on sexual function in female patients being treated for idiopathic overactive bladder: a systematic review

    Overactive bladder is a common condition which impacts quality of life within the spheres of physical, social, psychological, and sexual health [ 1 , 2 ]. The EpiLUTS highlighted the association of OAB symptoms, and its negative impact on sexual …

  18. 21-03-2024 | Progressive Supranuclear Palsy | ReviewPaper

    Management Strategies for Atypical Parkinsonism

    Atypical parkinsonism is a term usually used to describe three rare neurodegenerative parkinsonian disorders which are distinct pathological entities: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and multiple system …

  19. Open Access 06-02-2024 | OriginalPaper

    Development and Pilot Testing of an Algorithm-Based Approach to Anticholinergic Deprescribing in Older Patients

    In geriatric medicine, anticholinergic adverse drug reactions have increasingly become the focus of many interventions designed to assess or improve prescribing quality. Although anticholinergic drugs are useful in specific indications, their …

  20. Open Access 08-05-2024 | Alzheimer's Disease | Online First

    Differentiating Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer’s Disease: A Pragmatic Review for Clinicians

    This pragmatic review synthesises the current understanding of prodromal dementia with Lewy bodies (pDLB) and prodromal Alzheimer’s disease (pAD), including clinical presentations, neuropsychological profiles, neuropsychiatric symptoms …

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