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20-06-2023 | Thymoma | Original Article

Lobulated tumor contour as a predictor of preoperative tumor invasion of the lung or pericardium in thymoma patients

Authors: Kazuhisa Tanaka, Hidemi Suzuki, Terunaga Inage, Takamasa Ito, Yuichi Sakairi, Ichiro Yoshino

Published in: Surgery Today | Issue 2/2024

Abstract

Purpose

Preoperative investigations to detect invasion to neighboring organs are important for deciding on the most appropriate surgical approach for thymoma. We evaluated preoperative computed tomography (CT) findings in thymoma patients to identify the CT features associated with tumor invasion.

Methods

Clinicopathologic information on 193 patients who underwent surgical resection for thymoma at Chiba University Hospital between 2002 and 2016 was collected retrospectively. The surgical pathology identified invasion of thymoma in 35 patients: in the lung (n = 18), pericardium (n = 11), or both (n = 6). Contact lengths between the tumor contour and lung (CLTL) or pericardium (CLTP) were measured at the maximum section of the tumor on axial CT. Univariate and multivariate analyses were performed to analyze the relationship between pathological invasion of the lung or pericardium and the clinicopathologic features.

Results

The mean CLTL and CLTP were significantly longer in patients with invasion of the neighboring organs than in those without invasion. A lobulated tumor contour was identified in 95.6% of the patients with invasion of the neighboring organs. A multivariate analysis revealed that a lobulated tumor contour was significantly associated with both lung and pericardial invasion.

Conclusions

A lobulated tumor contour was significantly associated with lung and/or pericardial invasion in thymoma patients.

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Title: Lobulated tumor contour as a predictor of preoperative tumor invasion of the lung or pericardium in thymoma patients
Authors: Kazuhisa Tanaka
Hidemi Suzuki
Terunaga Inage
Takamasa Ito
Yuichi Sakairi
Ichiro Yoshino
Publication date: 20-06-2023
Publisher: Springer Nature Singapore
Keywords: Thymoma
Thymoma
Computed Tomography
Computed Tomography
Sternotomy
Published in: Surgery Today / Issue 2/2024
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-023-02719-4

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Springer Medicine

Lobulated tumor contour as a predictor of preoperative tumor invasion of the lung or pericardium in thymoma patients

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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