Skip to main content
Top
Published in: BMC Cardiovascular Disorders 1/2015

Open Access 01-12-2015 | Research article

The impact of social deprivation on mortality following acute myocardial infarction, stroke or subarachnoid haemorrhage: A record linkage study

Authors: Kymberley Thorne, John G. Williams, Ashley Akbari, Stephen E. Roberts

Published in: BMC Cardiovascular Disorders | Issue 1/2015

Login to get access

Abstract

Background

The impact of social deprivation on mortality following acute myocardial infarction (AMI), stroke and subarachnoid haemorrhage (SAH) is unclear. Our objectives were, firstly, to determine, for each condition, whether there was higher mortality following admission according to social deprivation and secondly, to determine how any higher mortality for deprived groups may be correlated with factors including patient demographics, timing of admission and hospital size.

Methods

Routinely collected, linked hospital inpatient, mortality and primary care data were analysed for patients admitted as an emergency to hospitals in Wales between 2004 and 2011 with AMI (n = 30,663), stroke (37,888) and SAH (1753). Logistic regression with Bonferroni correction was used to examine, firstly, any significant increases in mortality with social deprivation quintile and, secondly, the influence of patient demographics, timing of admission and hospital characteristics on any higher mortality among the most socially deprived groups.

Results

Mortality was 14.3 % at 30 days for AMI, 21.4 % for stroke and 35.6 % for SAH. Social deprivation was significantly associated with higher mortality for AMI (25 %; 95 % CI = 12 %, 40 %) higher for quintile V compared with I), stroke (24 %; 14 %, 34 %), and non-significantly for SAH (32 %; −7 %, 87 %).
The higher mortality at 30 days with increased social deprivation varied significantly according to patient age for AMI patients and time period for SAH. It was also highest for both AMI and stroke patients, although not significantly for female patients, for admissions on weekdays and during autumn months.

Conclusions

We have demonstrated a positive association between social deprivation and higher mortality following emergency admissions for both AMI and stroke. The study findings also suggest that the influence of patient demographics, timing of admission and hospital size on social inequalities in mortality are quite similar for AMI and stroke.
Appendix
Available only for authorised users
Literature
1.
go back to reference Nichols M et al. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013;34(39):3028–34.CrossRefPubMed Nichols M et al. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013;34(39):3028–34.CrossRefPubMed
2.
go back to reference Capewell S et al. Age, sex, and social trends in out-of-hospital cardiac deaths in Scotland 1986–95: a retrospective cohort study. Lancet. 2001;358(9289):1213–7.CrossRefPubMed Capewell S et al. Age, sex, and social trends in out-of-hospital cardiac deaths in Scotland 1986–95: a retrospective cohort study. Lancet. 2001;358(9289):1213–7.CrossRefPubMed
3.
go back to reference Vescio MF et al. Mortality at ages 50–59 and deprivation at early and late stages of the life course in Wales. J Epidemiol Community Health. 2009;63(1):56–63.CrossRefPubMed Vescio MF et al. Mortality at ages 50–59 and deprivation at early and late stages of the life course in Wales. J Epidemiol Community Health. 2009;63(1):56–63.CrossRefPubMed
4.
go back to reference Bernheim SM et al. Socioeconomic disparities in outcomes after acute myocardial infarction. Am Heart J. 2007;153(2):313–9.CrossRefPubMed Bernheim SM et al. Socioeconomic disparities in outcomes after acute myocardial infarction. Am Heart J. 2007;153(2):313–9.CrossRefPubMed
5.
go back to reference Chang WC et al. Effects of socioeconomic status on mortality after acute myocardial infarction. Am J Med. 2007;120(1):33–9.CrossRefPubMed Chang WC et al. Effects of socioeconomic status on mortality after acute myocardial infarction. Am J Med. 2007;120(1):33–9.CrossRefPubMed
6.
go back to reference Morrison C et al. Effect of socioeconomic group on incidence of, management of, and survival after myocardial infarction and coronary death: analysis of community coronary event register. BMJ. 1997;314(7080):541–6.CrossRefPubMedPubMedCentral Morrison C et al. Effect of socioeconomic group on incidence of, management of, and survival after myocardial infarction and coronary death: analysis of community coronary event register. BMJ. 1997;314(7080):541–6.CrossRefPubMedPubMedCentral
7.
go back to reference Chen R et al. Socioeconomic deprivation and survival after stroke: findings from the prospective South london stroke register of 1995 to 2011. Stroke. 2014;45(1):217–23.CrossRefPubMed Chen R et al. Socioeconomic deprivation and survival after stroke: findings from the prospective South london stroke register of 1995 to 2011. Stroke. 2014;45(1):217–23.CrossRefPubMed
8.
go back to reference Macleod MR, Andrews PJ. Effect of deprivation and gender on the incidence and management of acute brain disorders. Intensive Care Med. 2002;28(12):1729–34.CrossRefPubMed Macleod MR, Andrews PJ. Effect of deprivation and gender on the incidence and management of acute brain disorders. Intensive Care Med. 2002;28(12):1729–34.CrossRefPubMed
9.
10.
go back to reference Jakovljevic D et al. Socioeconomic status and ischemic stroke: The FINMONICA Stroke Register. Stroke. 2001;32(7):1492–8.CrossRefPubMed Jakovljevic D et al. Socioeconomic status and ischemic stroke: The FINMONICA Stroke Register. Stroke. 2001;32(7):1492–8.CrossRefPubMed
11.
go back to reference Kunst AE et al. Socioeconomic inequalities in stroke mortality among middle-aged men: an international overview. European Union Working Group on Socioeconomic Inequalities in Health. Stroke. 1998;29(11):2285–91.CrossRefPubMed Kunst AE et al. Socioeconomic inequalities in stroke mortality among middle-aged men: an international overview. European Union Working Group on Socioeconomic Inequalities in Health. Stroke. 1998;29(11):2285–91.CrossRefPubMed
12.
go back to reference Maheswaran R, Elliott P, Strachan DP. Socioeconomic deprivation, ethnicity, and stroke mortality in Greater London and south east England. J Epidemiol Community Health. 1997;51(2):127–31.CrossRefPubMedPubMedCentral Maheswaran R, Elliott P, Strachan DP. Socioeconomic deprivation, ethnicity, and stroke mortality in Greater London and south east England. J Epidemiol Community Health. 1997;51(2):127–31.CrossRefPubMedPubMedCentral
13.
go back to reference Ahacic K, Trygged S, Kareholt I. Income and education as predictors of stroke mortality after the survival of a first stroke. Stroke Res Treat. 2012;2012:983145.PubMedPubMedCentral Ahacic K, Trygged S, Kareholt I. Income and education as predictors of stroke mortality after the survival of a first stroke. Stroke Res Treat. 2012;2012:983145.PubMedPubMedCentral
14.
go back to reference Jakovljevic D et al. Socioeconomic differences in the incidence, mortality and prognosis of intracerebral hemorrhage in Finnish Adult Population. The FINMONICA Stroke Register. Neuroepidemiology. 2001;20(2):85–90.CrossRefPubMed Jakovljevic D et al. Socioeconomic differences in the incidence, mortality and prognosis of intracerebral hemorrhage in Finnish Adult Population. The FINMONICA Stroke Register. Neuroepidemiology. 2001;20(2):85–90.CrossRefPubMed
15.
go back to reference Hawkins NM et al. The UK National Health Service: delivering equitable treatment across the spectrum of coronary disease. Circ Cardiovasc Qual Outcomes. 2013;6(2):208–16.CrossRefPubMed Hawkins NM et al. The UK National Health Service: delivering equitable treatment across the spectrum of coronary disease. Circ Cardiovasc Qual Outcomes. 2013;6(2):208–16.CrossRefPubMed
16.
go back to reference Picciotto S et al. Associations of area based deprivation status and individual educational attainment with incidence, treatment, and prognosis of first coronary event in Rome, Italy. J Epidemiol Community Health. 2006;60(1):37–43.CrossRefPubMedPubMedCentral Picciotto S et al. Associations of area based deprivation status and individual educational attainment with incidence, treatment, and prognosis of first coronary event in Rome, Italy. J Epidemiol Community Health. 2006;60(1):37–43.CrossRefPubMedPubMedCentral
17.
go back to reference Fournier S et al. Influence of socioeconomic factors on delays, management and outcome amongst patients with acute myocardial infarction undergoing primary percutaneous coronary intervention. Swiss Med Wkly. 2013;143:w13817.PubMed Fournier S et al. Influence of socioeconomic factors on delays, management and outcome amongst patients with acute myocardial infarction undergoing primary percutaneous coronary intervention. Swiss Med Wkly. 2013;143:w13817.PubMed
18.
go back to reference Weir NU et al. Study of the relationship between social deprivation and outcome after stroke. Stroke. 2005;36(4):815–9.CrossRefPubMed Weir NU et al. Study of the relationship between social deprivation and outcome after stroke. Stroke. 2005;36(4):815–9.CrossRefPubMed
19.
go back to reference Wong KY et al. Effect of social deprivation on mortality and the duration of hospital stay after a stroke. Cerebrovasc Dis. 2006;22(4):251–7.CrossRefPubMed Wong KY et al. Effect of social deprivation on mortality and the duration of hospital stay after a stroke. Cerebrovasc Dis. 2006;22(4):251–7.CrossRefPubMed
20.
go back to reference Aslanyan S et al. Effect of area-based deprivation on the severity, subtype, and outcome of ischemic stroke. Stroke. 2003;34(11):2623–8.CrossRefPubMed Aslanyan S et al. Effect of area-based deprivation on the severity, subtype, and outcome of ischemic stroke. Stroke. 2003;34(11):2623–8.CrossRefPubMed
21.
22.
go back to reference Davies CA, Leyland AH. Trends and inequalities in short-term acute myocardial infarction case fatality in Scotland, 1988–2004. Popul Health Metr. 2010;8:33.CrossRefPubMedPubMedCentral Davies CA, Leyland AH. Trends and inequalities in short-term acute myocardial infarction case fatality in Scotland, 1988–2004. Popul Health Metr. 2010;8:33.CrossRefPubMedPubMedCentral
27.
go back to reference Roberts SE et al. Mortality following acute pancreatitis: social deprivation, hospital size and time of admission: record linkage study. BMC Gastroenterol. 2014;14:153.CrossRefPubMedPubMedCentral Roberts SE et al. Mortality following acute pancreatitis: social deprivation, hospital size and time of admission: record linkage study. BMC Gastroenterol. 2014;14:153.CrossRefPubMedPubMedCentral
28.
go back to reference Gale CP et al. Age-dependent inequalities in improvements in mortality occur early after acute myocardial infarction in 478,242 patients in the Myocardial Ischaemia National Audit Project (MINAP) registry. Int J Cardiol. 2013;168(2):881–7.CrossRefPubMed Gale CP et al. Age-dependent inequalities in improvements in mortality occur early after acute myocardial infarction in 478,242 patients in the Myocardial Ischaemia National Audit Project (MINAP) registry. Int J Cardiol. 2013;168(2):881–7.CrossRefPubMed
29.
go back to reference Chung SC et al. Acute myocardial infarction: a comparison of short-term survival in national outcome registries in Sweden and the UK. Lancet. 2014;383(9925):1305–12.CrossRefPubMedPubMedCentral Chung SC et al. Acute myocardial infarction: a comparison of short-term survival in national outcome registries in Sweden and the UK. Lancet. 2014;383(9925):1305–12.CrossRefPubMedPubMedCentral
30.
go back to reference Smolina K et al. Incidence and 30-day case fatality for acute myocardial infarction in England in 2010: national-linked database study. Eur J Public Health. 2012;22(6):848–53.CrossRefPubMedPubMedCentral Smolina K et al. Incidence and 30-day case fatality for acute myocardial infarction in England in 2010: national-linked database study. Eur J Public Health. 2012;22(6):848–53.CrossRefPubMedPubMedCentral
31.
go back to reference Bamford J et al. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project–1981-86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry. 1990;53(1):16–22.CrossRefPubMedPubMedCentral Bamford J et al. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project–1981-86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry. 1990;53(1):16–22.CrossRefPubMedPubMedCentral
32.
go back to reference Syme PD et al. Community-based stroke incidence in a Scottish population: the Scottish Borders Stroke Study. Stroke. 2005;36(9):1837–43.CrossRefPubMed Syme PD et al. Community-based stroke incidence in a Scottish population: the Scottish Borders Stroke Study. Stroke. 2005;36(9):1837–43.CrossRefPubMed
33.
go back to reference Pobereskin LH. Incidence and outcome of subarachnoid haemorrhage: a retrospective population based study. J Neurol Neurosurg Psychiatry. 2001;70(3):340–3.CrossRefPubMedPubMedCentral Pobereskin LH. Incidence and outcome of subarachnoid haemorrhage: a retrospective population based study. J Neurol Neurosurg Psychiatry. 2001;70(3):340–3.CrossRefPubMedPubMedCentral
34.
go back to reference Lovelock CE, Rinkel GJ, Rothwell PM. Time trends in outcome of subarachnoid hemorrhage: Population-based study and systematic review. Neurology. 2010;74(19):1494–501.CrossRefPubMedPubMedCentral Lovelock CE, Rinkel GJ, Rothwell PM. Time trends in outcome of subarachnoid hemorrhage: Population-based study and systematic review. Neurology. 2010;74(19):1494–501.CrossRefPubMedPubMedCentral
35.
go back to reference Macpherson KJ et al. Trends in incidence and in short term survival following a subarachnoid haemorrhage in Scotland, 1986–2005: a retrospective cohort study. BMC Neurol. 2011;11:38.CrossRefPubMedPubMedCentral Macpherson KJ et al. Trends in incidence and in short term survival following a subarachnoid haemorrhage in Scotland, 1986–2005: a retrospective cohort study. BMC Neurol. 2011;11:38.CrossRefPubMedPubMedCentral
36.
go back to reference Macintyre K et al. Relation between socioeconomic deprivation and death from a first myocardial infarction in Scotland: population based analysis. BMJ. 2001;322(7295):1152–3.CrossRefPubMedPubMedCentral Macintyre K et al. Relation between socioeconomic deprivation and death from a first myocardial infarction in Scotland: population based analysis. BMJ. 2001;322(7295):1152–3.CrossRefPubMedPubMedCentral
37.
go back to reference Lazzarino AI et al. Inequalities in stroke patients’ management in English public hospitals: a survey on 200,000 patients. PLoS One. 2011;6(3), e17219.CrossRefPubMedPubMedCentral Lazzarino AI et al. Inequalities in stroke patients’ management in English public hospitals: a survey on 200,000 patients. PLoS One. 2011;6(3), e17219.CrossRefPubMedPubMedCentral
38.
go back to reference Taylor FC et al. Socioeconomic deprivation is a predictor of poor postoperative cardiovascular outcomes in patients undergoing coronary artery bypass grafting. Heart. 2003;89(9):1062–6.CrossRefPubMedPubMedCentral Taylor FC et al. Socioeconomic deprivation is a predictor of poor postoperative cardiovascular outcomes in patients undergoing coronary artery bypass grafting. Heart. 2003;89(9):1062–6.CrossRefPubMedPubMedCentral
39.
go back to reference MacLeod MC et al. Geographic, demographic, and socioeconomic variations in the investigation and management of coronary heart disease in Scotland. Heart. 1999;81(3):252–6.CrossRefPubMedPubMedCentral MacLeod MC et al. Geographic, demographic, and socioeconomic variations in the investigation and management of coronary heart disease in Scotland. Heart. 1999;81(3):252–6.CrossRefPubMedPubMedCentral
40.
go back to reference Melville MR et al. Cardiac rehabilitation: socially deprived patients are less likely to attend but patients ineligible for thrombolysis are less likely to be invited. Heart. 1999;82(3):373–7.CrossRefPubMedPubMedCentral Melville MR et al. Cardiac rehabilitation: socially deprived patients are less likely to attend but patients ineligible for thrombolysis are less likely to be invited. Heart. 1999;82(3):373–7.CrossRefPubMedPubMedCentral
42.
go back to reference Hippisley-Cox J, Pringle M. Inequalities in access to coronary angiography and revascularisation: the association of deprivation and location of primary care services. Br J Gen Pract. 2000;50(455):449–54.PubMedPubMedCentral Hippisley-Cox J, Pringle M. Inequalities in access to coronary angiography and revascularisation: the association of deprivation and location of primary care services. Br J Gen Pract. 2000;50(455):449–54.PubMedPubMedCentral
43.
go back to reference Fareed N. Size matters: a meta-analysis on the impact of hospital size on patient mortality. Int J Evid Based Healthc. 2012;10(2):103–11.CrossRefPubMed Fareed N. Size matters: a meta-analysis on the impact of hospital size on patient mortality. Int J Evid Based Healthc. 2012;10(2):103–11.CrossRefPubMed
44.
go back to reference Charlton J et al. Impact of deprivation on occurrence, outcomes and health care costs of people with multiple morbidity. J Health Serv Res Policy. 2013;18(4):215–23.CrossRefPubMedPubMedCentral Charlton J et al. Impact of deprivation on occurrence, outcomes and health care costs of people with multiple morbidity. J Health Serv Res Policy. 2013;18(4):215–23.CrossRefPubMedPubMedCentral
45.
go back to reference Fone DL, Dunstan F. Mental health, places and people: a multilevel analysis of economic inactivity and social deprivation. Health Place. 2006;12(3):332–44.CrossRefPubMed Fone DL, Dunstan F. Mental health, places and people: a multilevel analysis of economic inactivity and social deprivation. Health Place. 2006;12(3):332–44.CrossRefPubMed
Metadata
Title
The impact of social deprivation on mortality following acute myocardial infarction, stroke or subarachnoid haemorrhage: A record linkage study
Authors
Kymberley Thorne
John G. Williams
Ashley Akbari
Stephen E. Roberts
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2015
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-015-0045-x

Other articles of this Issue 1/2015

BMC Cardiovascular Disorders 1/2015 Go to the issue