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Published in:

01-06-2008 | Review

The functions of herpesvirus-encoded microRNAs

Authors: Finn Grey, Lauren Hook, Jay Nelson

Published in: Medical Microbiology and Immunology | Issue 2/2008

Abstract

Bioinformatic and direct cloning approaches have led to the identification of over 100 novel miRNAs expressed in DNA viruses, although the function of the majority of these small regulatory RNA molecules is unclear. Recently, a number of reports have now identified potential targets of viral miRNAs, including cellular and viral genes as well as an ortholog of an important immuno-regulatory cellular miRNA. In this review, we will cover the identification and characterization of miRNAs expressed in the herpesvirus family and discuss the potential significance of their role in viral infection.

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Title: The functions of herpesvirus-encoded microRNAs
Authors: Finn Grey
Lauren Hook
Jay Nelson
Publication date: 01-06-2008
Publisher: Springer Berlin Heidelberg
Published in: Medical Microbiology and Immunology / Issue 2/2008
Print ISSN: 0300-8584
Electronic ISSN: 1432-1831
DOI: https://doi.org/10.1007/s00430-007-0070-1

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