Skip to main content
Top
Published in: Current Heart Failure Reports 5/2023

Open Access 04-09-2023 | Telemedicine

Telemedicine: an Effective and Low-Cost Lesson From the COVID-19 Pandemic for the Management of Heart Failure Patients

Authors: Paolo Severino, Silvia Prosperi, Andrea D’Amato, Claudia Cestiè, Vincenzo Myftari, Viviana Maestrini, Lucia Ilaria Birtolo, Domenico Filomena, Marco Valerio Mariani, Carlo Lavalle, Roberto Badagliacca, Massimo Mancone, Francesco Fedele, Carmine Dario Vizza

Published in: Current Heart Failure Reports | Issue 5/2023

Login to get access

Abstract

Purpose

The purpose of this review is to explore the benefits and controversies that telemedicine (TM), applied to patients with heart failure (HF), can provide in terms of diagnosis, therapeutic management, and prognosis improvement.

Recent Findings and Summary

During the coronavirus disease 19 (COVID-19) outbreak, TM emerged as the most effective and feasible method available to ensure continuous care for chronic diseases. Among these, HF, characterized by high mortality, morbidity, and the need for frequent visits, may benefit of the TM role. HF patients are affected by frequent exacerbations undergoing a progressive prognosis impoverishment, strongly depending on the disease’s management. A precise clinical handling is always required, with a constant optimization of the therapy, a continuous control of risk factors, and a sensitive attention to any change in symptoms, clinical signs, and laboratory tests. In this context, TM has shown to improve therapy adherence and HF: patients’ self-care, impacting the prognosis even if specific results are controversial. Major evidence shows that TM may allow an adequate primary prevention, reducing the impact of the main cardiovascular risk factors. TM can also be useful for the secondary prevention, early detecting a likely HF exacerbation before it becomes clinically manifest, thereby lowering the need for hospitalization. Moreover, an optimal up-titration of the therapy and an increase in treatment adherence are feasible by using TM. However, some studies did not show unambiguous results, and uncertainties still remain.

Graphical Abstract

Literature
1.
go back to reference Conrath DW, et al. An experimental evaluation of alternative communication systems as used for medical diagnosis. Behav Sci. 1975;20(5):296–305.CrossRefPubMed Conrath DW, et al. An experimental evaluation of alternative communication systems as used for medical diagnosis. Behav Sci. 1975;20(5):296–305.CrossRefPubMed
2.
go back to reference McDonagh TA, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2021;42(36):3599–726. https://doi.org/10.1093/eurheartj/ehab368.CrossRefPubMed McDonagh TA, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2021;42(36):3599–726. https://​doi.​org/​10.​1093/​eurheartj/​ehab368.CrossRefPubMed
3.
go back to reference Wootton R. Chronic disease management telemedicine. In: Trafton JA, Gordon WP, editors. pp 1–20 in Best practices in the behavioral management of chronic disease. Vol II Other medical disorders. Los Altos: Institute for Brain Potential; 2003. Wootton R. Chronic disease management telemedicine. In: Trafton JA, Gordon WP, editors. pp 1–20 in Best practices in the behavioral management of chronic disease. Vol II Other medical disorders. Los Altos: Institute for Brain Potential; 2003.
5.
go back to reference Severino P, et al. Clinical support through telemedicine in heart failure outpatients during the COVID-19 pandemic period: results of a 12-months follow up. J Clin Med. 2022;11(10):2790.CrossRefPubMedPubMedCentral Severino P, et al. Clinical support through telemedicine in heart failure outpatients during the COVID-19 pandemic period: results of a 12-months follow up. J Clin Med. 2022;11(10):2790.CrossRefPubMedPubMedCentral
10.
go back to reference Waters HUGH, Marlon G. The costs of chronic disease in the US. Santa Monica: The Milken Institute; 2018. Waters HUGH, Marlon G. The costs of chronic disease in the US. Santa Monica: The Milken Institute; 2018.
14.
go back to reference • Katula JA, et al. Effects of a digital diabetes prevention program: an RCT. Am J Prev Med. 2022; 62(4): 567–577. https://doi.org/10.1016/j.amepre.2021.10.023. Digital Diabetes Prevention Programs demonstrated promising results in improving the lifestyle, notably the weight and HbA1c among people with prediabetes. • Katula JA, et al. Effects of a digital diabetes prevention program: an RCT. Am J Prev Med. 2022; 62(4): 567–577. https://​doi.​org/​10.​1016/​j.​amepre.​2021.​10.​023. Digital Diabetes Prevention Programs demonstrated promising results in improving the lifestyle, notably the weight and HbA1c among people with prediabetes.
15.
go back to reference Ruberti OM, et al. Hypertension telemonitoring and home-based physical training programs. Blood Press. 2021;30(6):428–38.CrossRefPubMed Ruberti OM, et al. Hypertension telemonitoring and home-based physical training programs. Blood Press. 2021;30(6):428–38.CrossRefPubMed
16.
go back to reference Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Framingham study. Circulation. 1979;59(1):8–13.CrossRefPubMed Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Framingham study. Circulation. 1979;59(1):8–13.CrossRefPubMed
17.
go back to reference • Chow CK, Redfern J, Hillis GS, Thakkar J, Santo K, Hackett ML, et al.. Effect of lifestyle-focused text messaging on risk factor modification in patients with coronary heart disease: a randomized clinical trial. JAMA. 2015; 314(12):1255–1263. https://doi.org/10.1001/jama.2015.10945.2442937. Mobile apps and SMS text messages may encourage the changing of multiple behavioral risk factor, in particular of LDL cholesterol. • Chow CK, Redfern J, Hillis GS, Thakkar J, Santo K, Hackett ML, et al.. Effect of lifestyle-focused text messaging on risk factor modification in patients with coronary heart disease: a randomized clinical trial. JAMA. 2015; 314(12):1255–1263. https://​doi.​org/​10.​1001/​jama.​2015.​10945.​2442937. Mobile apps and SMS text messages may encourage the changing of multiple behavioral risk factor, in particular of LDL cholesterol.
18.
go back to reference Di Lenarda A, et al. The future of telemedicine for the management of heart failure patients: a Consensus Document of the Italian Association of Hospital Cardiologists (ANMCO), the Italian Society of Cardiology (SIC) and the Italian Society for Telemedicine and eHealth (Digital SIT). Eur Heart J Suppl. 2017;19(suppl_D):D113–29.CrossRefPubMedPubMedCentral Di Lenarda A, et al. The future of telemedicine for the management of heart failure patients: a Consensus Document of the Italian Association of Hospital Cardiologists (ANMCO), the Italian Society of Cardiology (SIC) and the Italian Society for Telemedicine and eHealth (Digital SIT). Eur Heart J Suppl. 2017;19(suppl_D):D113–29.CrossRefPubMedPubMedCentral
20.
go back to reference Koehler F, et al. Efficacy of telemedical interventional management in patients with heart failure (TIM-HF2): a randomised, controlled, parallel-group, unmasked trial. Lancet. 2018;392(10152):1047–57.CrossRefPubMed Koehler F, et al. Efficacy of telemedical interventional management in patients with heart failure (TIM-HF2): a randomised, controlled, parallel-group, unmasked trial. Lancet. 2018;392(10152):1047–57.CrossRefPubMed
21.
go back to reference Ding H, et al. The effects of telemonitoring on patient compliance with self-management recommendations and outcomes of the innovative telemonitoring enhanced care program for chronic heart failure: randomized controlled trial. J Med Internet Res. 2020;22(7): e17559.CrossRefPubMedPubMedCentral Ding H, et al. The effects of telemonitoring on patient compliance with self-management recommendations and outcomes of the innovative telemonitoring enhanced care program for chronic heart failure: randomized controlled trial. J Med Internet Res. 2020;22(7): e17559.CrossRefPubMedPubMedCentral
22.
go back to reference Imberti JF, et al. Remote monitoring and telemedicine in heart failure: implementation and benefits. Curr Cardiol Rep. 2021;23:1–11.CrossRef Imberti JF, et al. Remote monitoring and telemedicine in heart failure: implementation and benefits. Curr Cardiol Rep. 2021;23:1–11.CrossRef
23.
go back to reference • Piro A, Magnocavallo M, Della Rocca DG, Neccia M, Manzi G, Mariani MV, et al. Management of cardiac implantable electronic device follow-up in COVID-19 pandemic: lessons learned during Italian lockdown. J Cardiovasc Electrophysiol. 2020;31: 2814–2823. CIEDs are able to transmit data regarding intrathoracic impedance and early signs of HF allowing the medical team to undertake a timely clinical action. • Piro A, Magnocavallo M, Della Rocca DG, Neccia M, Manzi G, Mariani MV, et al. Management of cardiac implantable electronic device follow-up in COVID-19 pandemic: lessons learned during Italian lockdown. J Cardiovasc Electrophysiol. 2020;31: 2814–2823. CIEDs are able to transmit data regarding intrathoracic impedance and early signs of HF allowing the medical team to undertake a timely clinical action.
24.
go back to reference Magnocavallo M, Bernardini A, Mariani MV, Piro A, Marini M, Nicosia A, Adduci C, Rapacciuolo A, Saporito D, Grossi S, et al. Home delivery of the communicator for remote monitoring of cardiac implantable devices: a multicenter experience during the COVID-19 lockdown. Pacing Clin Electrophysiol. 2021;44:995–1003.CrossRefPubMedPubMedCentral Magnocavallo M, Bernardini A, Mariani MV, Piro A, Marini M, Nicosia A, Adduci C, Rapacciuolo A, Saporito D, Grossi S, et al. Home delivery of the communicator for remote monitoring of cardiac implantable devices: a multicenter experience during the COVID-19 lockdown. Pacing Clin Electrophysiol. 2021;44:995–1003.CrossRefPubMedPubMedCentral
25.
go back to reference • Abraham WT, et al. Sustained efficacy of pulmonary artery pressure to guide adjustment of chronic heart failure therapy: complete follow-up results from the CHAMPION randomised trial. Lancet. 2016; 387(10017): 453–461. Pulmonary artery pressure guided management may lead to a significant reduction in admissions to hospital. • Abraham WT, et al. Sustained efficacy of pulmonary artery pressure to guide adjustment of chronic heart failure therapy: complete follow-up results from the CHAMPION randomised trial. Lancet. 2016; 387(10017): 453–461. Pulmonary artery pressure guided management may lead to a significant reduction in admissions to hospital.
26.
go back to reference Brugts JJ, et al. Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet (2023). Brugts JJ, et al. Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet (2023).
27.
go back to reference Leclercq C, et al. Wearables, telemedicine, and artificial intelligence in arrhythmias and heart failure: Proceedings of the European Society of Cardiology Cardiovascular Round Table. Europace. 2022; 24(9): 1372–1383. Leclercq C, et al. Wearables, telemedicine, and artificial intelligence in arrhythmias and heart failure: Proceedings of the European Society of Cardiology Cardiovascular Round Table. Europace. 2022; 24(9): 1372–1383.
29.
go back to reference Hjorth-Hansen AK, et al. Feasibility and accuracy of tele-echocardiography, with examinations by nurses and interpretation by an expert via telemedicine, in an outpatient heart failure clinic. J Ultrasound Med. 2020;39(12):2313–23.CrossRefPubMed Hjorth-Hansen AK, et al. Feasibility and accuracy of tele-echocardiography, with examinations by nurses and interpretation by an expert via telemedicine, in an outpatient heart failure clinic. J Ultrasound Med. 2020;39(12):2313–23.CrossRefPubMed
30.
go back to reference Magelssen MI, et al. The clinical influence of hand-held ultrasound examinations by general practitioners in patients with suspected heart failure supported by tools for automatic quantification and telemedicine. Eur Heart J-Cardiovasc Imaging. 2022;23(Supplement_1):jeab289-309.CrossRef Magelssen MI, et al. The clinical influence of hand-held ultrasound examinations by general practitioners in patients with suspected heart failure supported by tools for automatic quantification and telemedicine. Eur Heart J-Cardiovasc Imaging. 2022;23(Supplement_1):jeab289-309.CrossRef
31.
go back to reference Girerd N, et al. Practical outpatient management of worsening chronic heart failure. Eur J Heart Fail. 2022;24(5):750–61.CrossRefPubMed Girerd N, et al. Practical outpatient management of worsening chronic heart failure. Eur J Heart Fail. 2022;24(5):750–61.CrossRefPubMed
32.
go back to reference Buss VH, et al. Primary prevention of cardiovascular disease and type 2 diabetes mellitus using mobile health technology: systematic review of the literature. J Med Internet Res. 2020;22(10): e21159.CrossRefPubMedPubMedCentral Buss VH, et al. Primary prevention of cardiovascular disease and type 2 diabetes mellitus using mobile health technology: systematic review of the literature. J Med Internet Res. 2020;22(10): e21159.CrossRefPubMedPubMedCentral
33.
go back to reference Bae JW, et al. mHealth interventions for lifestyle and risk factor modification in coronary heart disease: randomized controlled trial. JMIR Mhealth Uhealth. 2021;9(9): e29928.CrossRefPubMedPubMedCentral Bae JW, et al. mHealth interventions for lifestyle and risk factor modification in coronary heart disease: randomized controlled trial. JMIR Mhealth Uhealth. 2021;9(9): e29928.CrossRefPubMedPubMedCentral
34.
go back to reference Chaudhry SI, Mattera JA, Curtis JP, Spertus JA, Herrin J, Lin Z, et al. Telemonitoring in patients with heart failure. N Engl J Med. 2010;363:2301–9.CrossRefPubMedPubMedCentral Chaudhry SI, Mattera JA, Curtis JP, Spertus JA, Herrin J, Lin Z, et al. Telemonitoring in patients with heart failure. N Engl J Med. 2010;363:2301–9.CrossRefPubMedPubMedCentral
35.
go back to reference Lindenfeld J, Zile MR, Desai AS, Bhatt K, Ducharme A, Horstmanshof D, et al. Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial. Lancet. 2021;398:991–1001.CrossRefPubMed Lindenfeld J, Zile MR, Desai AS, Bhatt K, Ducharme A, Horstmanshof D, et al. Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial. Lancet. 2021;398:991–1001.CrossRefPubMed
37.
go back to reference • Thibodeau JT, and Gorodeski EZ. Telehealth for uptitration of guideline-directed medical therapy in heart failure. Circulation. 2020; 142(16): 1507–1509. TM has shown to be effective in obtaining an adequate uptitration of HF therapy, improving also therapeutic adherence. • Thibodeau JT, and Gorodeski EZ. Telehealth for uptitration of guideline-directed medical therapy in heart failure. Circulation. 2020; 142(16): 1507–1509. TM has shown to be effective in obtaining an adequate uptitration of HF therapy, improving also therapeutic adherence.
38.
go back to reference Rao VN, et al. In-hospital virtual peer-to-peer consultation to increase guideline-directed medical therapy for heart failure: a pilot randomized trial. Circ Heart Fail. 2023;16(2):e010158.PubMed Rao VN, et al. In-hospital virtual peer-to-peer consultation to increase guideline-directed medical therapy for heart failure: a pilot randomized trial. Circ Heart Fail. 2023;16(2):e010158.PubMed
39.
go back to reference Bhatt AS, et al. Virtual optimization of guideline-directed medical therapy in hospitalized patients with heart failure with reduced ejection fraction: the IMPLEMENT-HF pilot study. Eur J Heart Fail. 2021;23(7):1191–201.CrossRefPubMed Bhatt AS, et al. Virtual optimization of guideline-directed medical therapy in hospitalized patients with heart failure with reduced ejection fraction: the IMPLEMENT-HF pilot study. Eur J Heart Fail. 2021;23(7):1191–201.CrossRefPubMed
40.
go back to reference Bhatt AS, et al. Virtual care team guided management of patients with heart failure during hospitalization. J Am Coll Cardiol. 2023;81(17):1680–93.CrossRefPubMed Bhatt AS, et al. Virtual care team guided management of patients with heart failure during hospitalization. J Am Coll Cardiol. 2023;81(17):1680–93.CrossRefPubMed
41.
go back to reference Desai AS, et al. Remote optimization of guideline-directed medical therapy in patients with heart failure with reduced ejection fraction. JAMA Cardiol. 2020;5(12):1430–4.CrossRefPubMed Desai AS, et al. Remote optimization of guideline-directed medical therapy in patients with heart failure with reduced ejection fraction. JAMA Cardiol. 2020;5(12):1430–4.CrossRefPubMed
42.
go back to reference Gandapur Y, et al. The role of mHealth for improving medication adherence in patients with cardiovascular disease: a systematic review. Eur Heart J-Qual Care Clin Outcomes. 2016;2(4):237–44.CrossRefPubMedPubMedCentral Gandapur Y, et al. The role of mHealth for improving medication adherence in patients with cardiovascular disease: a systematic review. Eur Heart J-Qual Care Clin Outcomes. 2016;2(4):237–44.CrossRefPubMedPubMedCentral
43.
go back to reference Goldstein CM, et al. Randomized controlled feasibility trial of two telemedicine medication reminder systems for older adults with heart failure. J Telemed Telecare. 2014;20(6):293–9.CrossRefPubMedPubMedCentral Goldstein CM, et al. Randomized controlled feasibility trial of two telemedicine medication reminder systems for older adults with heart failure. J Telemed Telecare. 2014;20(6):293–9.CrossRefPubMedPubMedCentral
45.
go back to reference Vellone E, et al. Motivational interviewing to improve self-care in heart failure patients (MOTIVATE-HF): a randomized controlled trial. ESC Heart Fail. 2020;7(3):1309–18.CrossRefPubMedPubMedCentral Vellone E, et al. Motivational interviewing to improve self-care in heart failure patients (MOTIVATE-HF): a randomized controlled trial. ESC Heart Fail. 2020;7(3):1309–18.CrossRefPubMedPubMedCentral
46.
go back to reference Koehler F, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: the telemedical interventional monitoring in heart failure study. Circulation. 2011;123(17):1873–80.CrossRefPubMed Koehler F, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: the telemedical interventional monitoring in heart failure study. Circulation. 2011;123(17):1873–80.CrossRefPubMed
49.
go back to reference Jiménez-Marrero S, et al. Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial. J Telemed Telecare. 2020;26(1–2):64–72.CrossRefPubMed Jiménez-Marrero S, et al. Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial. J Telemed Telecare. 2020;26(1–2):64–72.CrossRefPubMed
51.
go back to reference Writing Committee Members; ACC/AHA Joint Committee Members. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. J Card Fail. 2022;28:e1–167.CrossRef Writing Committee Members; ACC/AHA Joint Committee Members. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. J Card Fail. 2022;28:e1–167.CrossRef
53.
go back to reference Zhu Y, Xiang G, Chao X. Effectiveness of telemedicine systems for adults with heart failure: a meta-analysis of randomized controlled trials. Heart Fail Rev. 2020;25:231–43.CrossRefPubMed Zhu Y, Xiang G, Chao X. Effectiveness of telemedicine systems for adults with heart failure: a meta-analysis of randomized controlled trials. Heart Fail Rev. 2020;25:231–43.CrossRefPubMed
Metadata
Title
Telemedicine: an Effective and Low-Cost Lesson From the COVID-19 Pandemic for the Management of Heart Failure Patients
Authors
Paolo Severino
Silvia Prosperi
Andrea D’Amato
Claudia Cestiè
Vincenzo Myftari
Viviana Maestrini
Lucia Ilaria Birtolo
Domenico Filomena
Marco Valerio Mariani
Carlo Lavalle
Roberto Badagliacca
Massimo Mancone
Francesco Fedele
Carmine Dario Vizza
Publication date
04-09-2023
Publisher
Springer US
Published in
Current Heart Failure Reports / Issue 5/2023
Print ISSN: 1546-9530
Electronic ISSN: 1546-9549
DOI
https://doi.org/10.1007/s11897-023-00624-y

Other articles of this Issue 5/2023

Current Heart Failure Reports 5/2023 Go to the issue
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.