Published in:
16-03-2024 | Targeted Therapy | Editorial
From gene panel testing to new molecularly targeted therapy
Author:
Noriomi Matsumura
Published in:
International Cancer Conference Journal
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Issue 2/2024
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Excerpt
This issue includes a report of a case of MET-amplified neuroendocrine cancer detected by gene panel testing that responded to capmatinib [
1]. Capmatinib is approved by the Food and Drug Administration for non-small cell lung cancer with MET exon 14 skipping. However, capmatinib is not approved for MET amplification. Capmatinib was given to this patient under the Patient Application for Multiple Molecularly Targeted Therapies Based on Gene Profiling by Gene Panel Testing programme (jRCTs031190104) [
2]. This case report is a good example of the discovery of a novel molecularly targeted therapy based on gene panel testing. …