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14-02-2024 | Lenvatinib | Case report - Complication

A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab

Authors: Masahiro Kurokawa, Daiki Ikarashi, Renpei Kato, Mitsugu Kanehira, Takashi Fukagai, Wataru Obara

Published in: International Cancer Conference Journal | Issue 2/2024

Abstract

Pancreatic injury is a rare, but noted complication of nephrectomy. We report a case involving a 56-year-old man who presented with cT3bN0M0 left locally advanced renal cell carcinoma with an inferior vena cava thrombus. Nephrectomy with thrombectomy was performed given the remarkable shrinkage of the primary tumor and thrombus following lenvatinib plus pembrolizumab administration. The patient developed postoperative pancreatitis associated with unrecognized minor pancreatic injury, which was treated conservatively. To our knowledge, this has been the first case that underwent nephrectomy for RCC with an IVC thrombus after presurgical lenvatinib plus pembrolizumab and received conservative treatment for postoperative pancreatitis.

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Title: A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab
Authors: Masahiro Kurokawa
Daiki Ikarashi
Renpei Kato
Mitsugu Kanehira
Takashi Fukagai
Wataru Obara
Publication date: 14-02-2024
Publisher: Springer Nature Singapore
Keywords: Lenvatinib
Kidney Cancer
Kidney Cancer
Kidney Cancer
Pancreatitis
Nephrectomy
Nephrectomy
Nephrectomy
Computed Tomography
Computed Tomography
Thrombectomy
Autoimmune Pancreatitis
Published in: International Cancer Conference Journal / Issue 2/2024
Electronic ISSN: 2192-3183
DOI: https://doi.org/10.1007/s13691-024-00657-7

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