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Published in: Journal of NeuroVirology 3/2013

01-06-2013 | Case Report

Susac syndrome in a patient with human immunodeficiency virus infection

Authors: Erin E. Longbrake, Beau M. Ances, Ryan B. Viets, David B. Clifford

Published in: Journal of NeuroVirology | Issue 3/2013

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Excerpt

Susac syndrome (SS) is a diagnosis of exclusion based on findings of encephalopathy, branch retinal artery occlusions (BRAO), and hearing loss (Susac et al. 1979). These components may occur simultaneously or be temporally separated. The diagnosis is strongly supported by pathognomic involvement of the body of the corpus callosum on MRI; deep gray matter lesions, gadolinium enhancing lesions, and leptomeningeal enhancement may also be seen (Susac et al. 2003). …
Literature
go back to reference Carroll MB, Holmes R (2011) Dermatomyositis and HIV infection: case report and review of the literature. Rheumatol Int 31:673–679PubMedCrossRef Carroll MB, Holmes R (2011) Dermatomyositis and HIV infection: case report and review of the literature. Rheumatol Int 31:673–679PubMedCrossRef
go back to reference Dorr J, Radbruch H, Bock M, Wuerfel J, Bruggemann A, Wandinger KP, Zeise D, Pfueller CF, Zipp F, Paul F (2009) Encephalopathy, visual disturbance and hearing loss—recognizing the symptoms of Susac syndrome. Nat Rev Neurol 5:683–688PubMedCrossRef Dorr J, Radbruch H, Bock M, Wuerfel J, Bruggemann A, Wandinger KP, Zeise D, Pfueller CF, Zipp F, Paul F (2009) Encephalopathy, visual disturbance and hearing loss—recognizing the symptoms of Susac syndrome. Nat Rev Neurol 5:683–688PubMedCrossRef
go back to reference Gordon DL, Hayreh SS, Adams HP Jr (1991) Microangiopathy of the brain, retina, and ear: improvement without immunosuppressive therapy. Stroke 22:933–937PubMedCrossRef Gordon DL, Hayreh SS, Adams HP Jr (1991) Microangiopathy of the brain, retina, and ear: improvement without immunosuppressive therapy. Stroke 22:933–937PubMedCrossRef
go back to reference Jarius S, Neumayer B, Wandinger KP, Hartmann M, Wildemann B (2009) Anti-endothelial serum antibodies in a patient with Susac’s syndrome. J Neurol Sci 285:259–261PubMedCrossRef Jarius S, Neumayer B, Wandinger KP, Hartmann M, Wildemann B (2009) Anti-endothelial serum antibodies in a patient with Susac’s syndrome. J Neurol Sci 285:259–261PubMedCrossRef
go back to reference Kieburtz KD, Ketonen L, Zettelmaier AE, Kido D, Caine ED, Simon JH (1990) Magnetic resonance imaging findings in HIV cognitive impairment. Arch Neurol 47:643–645PubMedCrossRef Kieburtz KD, Ketonen L, Zettelmaier AE, Kido D, Caine ED, Simon JH (1990) Magnetic resonance imaging findings in HIV cognitive impairment. Arch Neurol 47:643–645PubMedCrossRef
go back to reference Magro CM, Poe JC, Lubow M, Susac JO (2011) Susac syndrome: an organ-specific autoimmune endotheliopathy syndrome associated with anti-endothelial cell antibodies. Am J Clin Pathol 136:903–912PubMedCrossRef Magro CM, Poe JC, Lubow M, Susac JO (2011) Susac syndrome: an organ-specific autoimmune endotheliopathy syndrome associated with anti-endothelial cell antibodies. Am J Clin Pathol 136:903–912PubMedCrossRef
go back to reference Rajadhyaksha A, Baheti TG, Mehra S, Sonawale AS, Jain N (2012) Dermatomyositis: a rare presentation of HIV seroconversion illness. J Clin Rheumatol 18:298–300PubMedCrossRef Rajadhyaksha A, Baheti TG, Mehra S, Sonawale AS, Jain N (2012) Dermatomyositis: a rare presentation of HIV seroconversion illness. J Clin Rheumatol 18:298–300PubMedCrossRef
go back to reference Susac JO, Hardman JM, Selhorst JB (1979) Microangiopathy of the brain and retina. Neurology 29:313–316PubMedCrossRef Susac JO, Hardman JM, Selhorst JB (1979) Microangiopathy of the brain and retina. Neurology 29:313–316PubMedCrossRef
go back to reference Susac JO, Murtagh FR, Egan RA, Berger JR, Bakshi R, Lincoff N, Gean AD, Galetta SL, Fox RJ, Costello FE, Lee AG, Clark J, Layzer RB, Daroff RB (2003) MRI findings in Susac’s syndrome. Neurology 61:1783–1787PubMedCrossRef Susac JO, Murtagh FR, Egan RA, Berger JR, Bakshi R, Lincoff N, Gean AD, Galetta SL, Fox RJ, Costello FE, Lee AG, Clark J, Layzer RB, Daroff RB (2003) MRI findings in Susac’s syndrome. Neurology 61:1783–1787PubMedCrossRef
go back to reference Vryonis E, Kakalou E, Baxevanakis A, Linardi C, Papanikolaou K, Papastamopoulos V, Baraboutis I, Skoutelis A (2011) P2180 Susac's syndrome in a HIV-infected patient. Clin Microbiol Inf 17 (suppl 4), p S651 Vryonis E, Kakalou E, Baxevanakis A, Linardi C, Papanikolaou K, Papastamopoulos V, Baraboutis I, Skoutelis A (2011) P2180 Susac's syndrome in a HIV-infected patient. Clin Microbiol Inf 17 (suppl 4), p S651
Metadata
Title
Susac syndrome in a patient with human immunodeficiency virus infection
Authors
Erin E. Longbrake
Beau M. Ances
Ryan B. Viets
David B. Clifford
Publication date
01-06-2013
Publisher
Springer US
Published in
Journal of NeuroVirology / Issue 3/2013
Print ISSN: 1355-0284
Electronic ISSN: 1538-2443
DOI
https://doi.org/10.1007/s13365-013-0164-z

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