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Published in: Journal of Neurology 8/2020

01-08-2020 | Subarachnoid Hemorrhage | Neurological Update

The changing face of neurosurgery for the older person

Authors: Ellie Edlmann, Peter C. Whitfield

Published in: Journal of Neurology | Issue 8/2020

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Abstract

Increased life expectancy and illness prevention and treatment have led to a growing population of older patients. These changes in patient population are apparent in neurosurgery; however, relatively little is reported about specific outcomes and prognostication in this group. This review summarises the challenges and management changes occurring in the treatment of three common neurosurgical pathologies; aneurysmal subarachnoid haemorrhage, head injury, and haemorrhagic stroke. A move towards less invasive neurosurgical techniques has implications on the risk–benefit profile of interventions. This creates the opportunity to intervene in older patients with greater co-morbidity, as long as improved outcomes can be evidenced. A critical part of assessing appropriateness for surgical intervention in older patients may be to change from a mindset of age to one of frailty and growing interest in scales assessing this may aid treatment decisions in the future.
Literature
2.
go back to reference Andrews PJD, Sinclair HL, Rodriguez A, Harris BA, Battison CG, Rhodes JKJ, Murray GD (2015) Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. N Engl J Med 373:2403–2412PubMed Andrews PJD, Sinclair HL, Rodriguez A, Harris BA, Battison CG, Rhodes JKJ, Murray GD (2015) Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. N Engl J Med 373:2403–2412PubMed
3.
go back to reference Beekman R, Chu S, Sommaruga S, King Z, Kamel H, Matouk C, Hwang D, Sheth K, Falcone G (2018) Spontaneous intracerebral hemorrhage in the elderly population (S10.006). Neurology 90:S10.006 Beekman R, Chu S, Sommaruga S, King Z, Kamel H, Matouk C, Hwang D, Sheth K, Falcone G (2018) Spontaneous intracerebral hemorrhage in the elderly population (S10.006). Neurology 90:S10.006
4.
go back to reference Brennan PM, Kolias AG, Joannides AJ, Shapey J, Marcus HJ, Gregson BA, Grover PJ, Hutchinson PJ, Coulter IC (2017) The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom. J Neurosurg 127:732–739PubMed Brennan PM, Kolias AG, Joannides AJ, Shapey J, Marcus HJ, Gregson BA, Grover PJ, Hutchinson PJ, Coulter IC (2017) The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom. J Neurosurg 127:732–739PubMed
5.
go back to reference Chesnut RM, Temkin N, Carney N, Dikmen S, Rondina C, Videtta W, Petroni G, Lujan S, Pridgeon J, Barber J, Machamer J, Chaddock K, Celix JM, Cherner M, Hendrix T, Global Neurotrauma Research G (2012) A trial of intracranial-pressure monitoring in traumatic brain injury. N Engl J Med 367:2471–2481PubMedPubMedCentral Chesnut RM, Temkin N, Carney N, Dikmen S, Rondina C, Videtta W, Petroni G, Lujan S, Pridgeon J, Barber J, Machamer J, Chaddock K, Celix JM, Cherner M, Hendrix T, Global Neurotrauma Research G (2012) A trial of intracranial-pressure monitoring in traumatic brain injury. N Engl J Med 367:2471–2481PubMedPubMedCentral
6.
go back to reference Chibbaro S, Di Rocco F, Makiese O, Mirone G, Marsella M, Lukaszewicz AC, Vicaut E, Turner B, Hamdi S, Spiriev T, Di Emidio P, Pirracchio R, Payen D, George B, Bresson D (2010) Neurosurgery and elderly: analysis through the years. Neurosurg Rev 34:229–234PubMed Chibbaro S, Di Rocco F, Makiese O, Mirone G, Marsella M, Lukaszewicz AC, Vicaut E, Turner B, Hamdi S, Spiriev T, Di Emidio P, Pirracchio R, Payen D, George B, Bresson D (2010) Neurosurgery and elderly: analysis through the years. Neurosurg Rev 34:229–234PubMed
7.
go back to reference Cooper DJ, Rosenfeld JV, Murray L, Arabi YM, Davies AR, D'Urso P, Kossmann T, Ponsford J, Seppelt I, Reilly P, Wolfe R (2011) Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med 364:1493–1502PubMed Cooper DJ, Rosenfeld JV, Murray L, Arabi YM, Davies AR, D'Urso P, Kossmann T, Ponsford J, Seppelt I, Reilly P, Wolfe R (2011) Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med 364:1493–1502PubMed
8.
go back to reference Edlmann E (2017) Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy. J Neuroinflamm 14:108 Edlmann E (2017) Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy. J Neuroinflamm 14:108
9.
go back to reference Emich S, Richling B, McCoy MR, Al-Schameri RA, Ling F, Sun L, Wang Y, Hitzl W (2014) The efficacy of dexamethasone on reduction in the reoperation rate of chronic subdural hematoma–the DRESH study: straightforward study protocol for a randomized controlled trial. Trials 15:6PubMedPubMedCentral Emich S, Richling B, McCoy MR, Al-Schameri RA, Ling F, Sun L, Wang Y, Hitzl W (2014) The efficacy of dexamethasone on reduction in the reoperation rate of chronic subdural hematoma–the DRESH study: straightforward study protocol for a randomized controlled trial. Trials 15:6PubMedPubMedCentral
10.
go back to reference Evans LR, Jones J, Lee HQ, Ganter D, Jaison A, Matthew J, Fitzgerald MC, Rosenfeld JV, Hunn MK, Tee JW (2019) Prognosis of acute subdural hematoma in the elderly: a systematic review. J Neurotrauma 36:517–522PubMed Evans LR, Jones J, Lee HQ, Ganter D, Jaison A, Matthew J, Fitzgerald MC, Rosenfeld JV, Hunn MK, Tee JW (2019) Prognosis of acute subdural hematoma in the elderly: a systematic review. J Neurotrauma 36:517–522PubMed
11.
go back to reference Farhat JS, Velanovich V, Falvo AJ, Horst HM, Swartz A, Patton JH Jr, Rubinfeld IS (2012) Are the frail destined to fail? Frailty index as predictor of surgical morbidity and mortality in the elderly. J Trauma Acute Care Surg 72:1526–1530 discussion 1530-1521 PubMed Farhat JS, Velanovich V, Falvo AJ, Horst HM, Swartz A, Patton JH Jr, Rubinfeld IS (2012) Are the frail destined to fail? Frailty index as predictor of surgical morbidity and mortality in the elderly. J Trauma Acute Care Surg 72:1526–1530 discussion 1530-1521 PubMed
12.
go back to reference Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G (2004) Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol Ser A Biol Sci Med Sci 59:255–263 Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G (2004) Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol Ser A Biol Sci Med Sci 59:255–263
13.
go back to reference Gardner RC, Dams-O'Connor K, Morrissey MR, Manley GT (2018) Geriatric traumatic brain injury: epidemiology, outcomes, knowledge gaps, and future directions. J Neurotrauma 35:889-906 Gardner RC, Dams-O'Connor K, Morrissey MR, Manley GT (2018) Geriatric traumatic brain injury: epidemiology, outcomes, knowledge gaps, and future directions. J Neurotrauma 35:889-906
14.
go back to reference Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, Lane K, McBee N, Mayo SW, Bistran-Hall AJ, Gandhi D, Mould WA, Ullman N, Ali H, Carhuapoma JR, Kase CS, Lees KR, Dawson J, Wilson A, Betz JF, Sugar EA, Hao Y, Avadhani R, Caron J-L, Harrigan MR, Carlson AP, Bulters D, LeDoux D, Huang J, Cobb C, Gupta G, Kitagawa R, Chicoine MR, Patel H, Dodd R, Camarata PJ, Wolfe S, Stadnik A, Money PL, Mitchell P, Sarabia R, Harnof S, Barzo P, Unterberg A, Teitelbaum JS, Wang W, Anderson CS, Mendelow AD, Gregson B, Janis S, Vespa P, Ziai W, Zuccarello M, Awad IA, Abdul-Rahim A, Abou-Hamden A, Abraham M, Ahmed A, Alba CA, Aldrich EF, Altschul D, Amin-Hanjani S, Anderson D, Ansari S, Antezana D, Ardelt A, Arikan F, Baguena M, Baker A, Barrer SJ, Becker KJ, Bergman T, Boström A, Braun J, Brindley P, Broaddus WC, Brown R, Buki A, Cao B, Cao Y, Carrion-Penagos J, Chalela J, Chang T, Chorro IM, Chowdhry S, Corral L, Csiba L, Davies J, Díaz AT, Derdeyn CP, Diringer M, Dlugash R, Ecker R, Economas T, Enriquez P, Ezer E, Fan Y, Feng H, Franz D, Freeman WD, Fusco M, Galicich W, Gelea ML, Goldstein J, Gonzalez AC, Grabarits C, Greenberg S, Gress D, Gu E, Hall C, Hernandez FM, Hoesch R, Hoh BL, Houser J, Hu R, Huang Y, Hussain MA, Insinga S, Jadhav A, Jaffe J, Jahromi BS, Jallo J, James M, James RF, Jankowitz B, Jeon E, Jichici D, Jonczak K, Jonker B, Karlen N, Keric N, Kerz T, Knopman J, Koenig C, Krishnamurthy S, Kumar A, Kureshi I, Laidlaw J, Lakhanpal A, Latorre JG, Leifer D, Leiphart J, Lenington S, Li Y, Lopez G, Lovick D, Lumenta C, Luo J, Maas MB, MacDonald J, MacKenzie L, Madan V, Majkowski R, Major O, Malhorta R, Malkoff M, Mangat H, Maswadeh A, Matouk C, McArthur K, McCaul S, Medow J, Mezey G, Mighty J, Miller D, Mohan KK, Muir K, Muñoz L, Nakaji P, Nee A, Nekoovaght-Tak S, Nyquist P, O'Kane R, Okasha M, O'Kelly C, Ostapkovich N, Pandey A, Parry-Jones A, Perla KR, Pollack A, Polster S, Pouratian N, Quinn T, Rajajee V, Reddy K, Rehman M, Reimer R, Rincon F, Rybinnik I, Sanchez B, Sansing L, Schneck M, Schuerer L, Schul D, Schweitzer J, Seder DB, Seyfried D, Sheth K, Spiotta A, Stechison M, Szabo K, Tamayo G, Tanczos K, Taussky P, Terry J, Testai F, Thomas K, Thompson CB, Thompson G, Torner JC, Tran H, Tucker K, Ungar L, Varelas P, Vargas NM, Vatter H, Venkatasubramanian C, Vermillion K, Vollmer D, Wang Y, Wang Y, Wen J, Whitworth LT, Willis B, Wrencher M, Wright SE, Xu Y, Yanase L, Yi X, Yu Z, Zomorodi A (2019) Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. The Lancet 393:1021–1032 Hanley DF, Thompson RE, Rosenblum M, Yenokyan G, Lane K, McBee N, Mayo SW, Bistran-Hall AJ, Gandhi D, Mould WA, Ullman N, Ali H, Carhuapoma JR, Kase CS, Lees KR, Dawson J, Wilson A, Betz JF, Sugar EA, Hao Y, Avadhani R, Caron J-L, Harrigan MR, Carlson AP, Bulters D, LeDoux D, Huang J, Cobb C, Gupta G, Kitagawa R, Chicoine MR, Patel H, Dodd R, Camarata PJ, Wolfe S, Stadnik A, Money PL, Mitchell P, Sarabia R, Harnof S, Barzo P, Unterberg A, Teitelbaum JS, Wang W, Anderson CS, Mendelow AD, Gregson B, Janis S, Vespa P, Ziai W, Zuccarello M, Awad IA, Abdul-Rahim A, Abou-Hamden A, Abraham M, Ahmed A, Alba CA, Aldrich EF, Altschul D, Amin-Hanjani S, Anderson D, Ansari S, Antezana D, Ardelt A, Arikan F, Baguena M, Baker A, Barrer SJ, Becker KJ, Bergman T, Boström A, Braun J, Brindley P, Broaddus WC, Brown R, Buki A, Cao B, Cao Y, Carrion-Penagos J, Chalela J, Chang T, Chorro IM, Chowdhry S, Corral L, Csiba L, Davies J, Díaz AT, Derdeyn CP, Diringer M, Dlugash R, Ecker R, Economas T, Enriquez P, Ezer E, Fan Y, Feng H, Franz D, Freeman WD, Fusco M, Galicich W, Gelea ML, Goldstein J, Gonzalez AC, Grabarits C, Greenberg S, Gress D, Gu E, Hall C, Hernandez FM, Hoesch R, Hoh BL, Houser J, Hu R, Huang Y, Hussain MA, Insinga S, Jadhav A, Jaffe J, Jahromi BS, Jallo J, James M, James RF, Jankowitz B, Jeon E, Jichici D, Jonczak K, Jonker B, Karlen N, Keric N, Kerz T, Knopman J, Koenig C, Krishnamurthy S, Kumar A, Kureshi I, Laidlaw J, Lakhanpal A, Latorre JG, Leifer D, Leiphart J, Lenington S, Li Y, Lopez G, Lovick D, Lumenta C, Luo J, Maas MB, MacDonald J, MacKenzie L, Madan V, Majkowski R, Major O, Malhorta R, Malkoff M, Mangat H, Maswadeh A, Matouk C, McArthur K, McCaul S, Medow J, Mezey G, Mighty J, Miller D, Mohan KK, Muir K, Muñoz L, Nakaji P, Nee A, Nekoovaght-Tak S, Nyquist P, O'Kane R, Okasha M, O'Kelly C, Ostapkovich N, Pandey A, Parry-Jones A, Perla KR, Pollack A, Polster S, Pouratian N, Quinn T, Rajajee V, Reddy K, Rehman M, Reimer R, Rincon F, Rybinnik I, Sanchez B, Sansing L, Schneck M, Schuerer L, Schul D, Schweitzer J, Seder DB, Seyfried D, Sheth K, Spiotta A, Stechison M, Szabo K, Tamayo G, Tanczos K, Taussky P, Terry J, Testai F, Thomas K, Thompson CB, Thompson G, Torner JC, Tran H, Tucker K, Ungar L, Varelas P, Vargas NM, Vatter H, Venkatasubramanian C, Vermillion K, Vollmer D, Wang Y, Wang Y, Wen J, Whitworth LT, Willis B, Wrencher M, Wright SE, Xu Y, Yanase L, Yi X, Yu Z, Zomorodi A (2019) Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. The Lancet 393:1021–1032
15.
go back to reference Henaux PL, Le Reste PJ, Laviolle B, Morandi X (2017) Steroids in chronic subdural hematomas (SUCRE trial): study protocol for a randomized controlled trial. Trials 18:252PubMedPubMedCentral Henaux PL, Le Reste PJ, Laviolle B, Morandi X (2017) Steroids in chronic subdural hematomas (SUCRE trial): study protocol for a randomized controlled trial. Trials 18:252PubMedPubMedCentral
16.
go back to reference Hutchinson PJ, Kolias AG, Timofeev IS, Corteen EA, Czosnyka M, Timothy J, Anderson I, Bulters DO, Belli A, Eynon CA, Wadley J, Mendelow AD, Mitchell PM, Wilson MH, Critchley G, Sahuquillo J, Unterberg A, Servadei F, Teasdale GM, Pickard JD, Menon DK, Murray GD, Kirkpatrick PJ (2016) Trial of decompressive craniectomy for traumatic intracranial hypertension. N Engl J Med 375:1119–1130PubMed Hutchinson PJ, Kolias AG, Timofeev IS, Corteen EA, Czosnyka M, Timothy J, Anderson I, Bulters DO, Belli A, Eynon CA, Wadley J, Mendelow AD, Mitchell PM, Wilson MH, Critchley G, Sahuquillo J, Unterberg A, Servadei F, Teasdale GM, Pickard JD, Menon DK, Murray GD, Kirkpatrick PJ (2016) Trial of decompressive craniectomy for traumatic intracranial hypertension. N Engl J Med 375:1119–1130PubMed
18.
go back to reference Koffijberg H, Buskens E, Rinkel GJE (2011) Aneurysm occlusion in elderly patients with aneurysmal subarachnoid haemorrhage: a cost–utility analysis. J Neurol Neurosurg Psychiatry 82:718–727PubMed Koffijberg H, Buskens E, Rinkel GJE (2011) Aneurysm occlusion in elderly patients with aneurysmal subarachnoid haemorrhage: a cost–utility analysis. J Neurol Neurosurg Psychiatry 82:718–727PubMed
19.
go back to reference Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Whitfield P, Gherle M, Caldwell K, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Brennan P, Belli A, Bond S, Turner C, Whitehead L, Wilkinson I, Hutchinson PJ (2018) Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial. Trials 19:670PubMedPubMedCentral Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, Owusu-Agyemang K, Al-Tamimi YZ, Gatt D, Thomson S, Anderson IA, Richards O, Whitfield P, Gherle M, Caldwell K, Davis-Wilkie C, Tarantino S, Barton G, Marcus HJ, Chari A, Brennan P, Belli A, Bond S, Turner C, Whitehead L, Wilkinson I, Hutchinson PJ (2018) Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial. Trials 19:670PubMedPubMedCentral
20.
go back to reference Lucke-Wold B, Turner R, Josiah D, Knotts C, Bhatia S (2016) Do age and anticoagulants affect the natural history of acute subdural hematomas? Arch Emerg Med Cri Care 1:1010 Lucke-Wold B, Turner R, Josiah D, Knotts C, Bhatia S (2016) Do age and anticoagulants affect the natural history of acute subdural hematomas? Arch Emerg Med Cri Care 1:1010
21.
go back to reference McDougall CG, Spetzler RF, Zabramski JM, Partovi S, Hills NK, Nakaji P, Albuquerque FC (2012) The barrow ruptured aneurysm. Trial 116:135 McDougall CG, Spetzler RF, Zabramski JM, Partovi S, Hills NK, Nakaji P, Albuquerque FC (2012) The barrow ruptured aneurysm. Trial 116:135
22.
go back to reference Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT, Karimi A, Shaw MD, Barer DH (2005) Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 365:387–397PubMed Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT, Karimi A, Shaw MD, Barer DH (2005) Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 365:387–397PubMed
23.
go back to reference Mendelow AD, Gregson BA, Rowan EN, Murray GD, Gholkar A, Mitchell PM (2013) Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial. Lancet 382:397–408PubMedPubMedCentral Mendelow AD, Gregson BA, Rowan EN, Murray GD, Gholkar A, Mitchell PM (2013) Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial. Lancet 382:397–408PubMedPubMedCentral
24.
go back to reference Miah IP, Holl DC, Peul WC, Walchenbach R, Kruyt N, de Laat K, Koot RW, Volovici V, Dirven CMF, van Kooten F, Kho KH, den Hertog HM, van der Naalt J, Jacobs B, Groen RJM, Lingsma HF, Dammers R, Jellema K, van der Gaag NA (2018) Dexamethasone therapy versus surgery for chronic subdural haematoma (DECSA trial): study protocol for a randomised controlled trial. Trials 19:575PubMedPubMedCentral Miah IP, Holl DC, Peul WC, Walchenbach R, Kruyt N, de Laat K, Koot RW, Volovici V, Dirven CMF, van Kooten F, Kho KH, den Hertog HM, van der Naalt J, Jacobs B, Groen RJM, Lingsma HF, Dammers R, Jellema K, van der Gaag NA (2018) Dexamethasone therapy versus surgery for chronic subdural haematoma (DECSA trial): study protocol for a randomised controlled trial. Trials 19:575PubMedPubMedCentral
25.
go back to reference Molyneux A (2002) International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. The Lancet 360:1267–1274 Molyneux A (2002) International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. The Lancet 360:1267–1274
26.
go back to reference National Institute for Health and Clinical Excellence (NICE) (2014) Head injury: assessment and early management clinical guidelines [CG176]. In: National Institute for Health and Clinical Excellence (NICE) (2014) Head injury: assessment and early management clinical guidelines [CG176]. In:
27.
go back to reference Nieuwkamp DJ, Rinkel GJE, Silva R, Greebe P, Schokking DA, Ferro JM (2006) Subarachnoid haemorrhage in patients %3e or = 75 years: clinical course, treatment and outcome. J Neurol Neurosurg Psychiatry 77:933–937PubMedPubMedCentral Nieuwkamp DJ, Rinkel GJE, Silva R, Greebe P, Schokking DA, Ferro JM (2006) Subarachnoid haemorrhage in patients %3e or = 75 years: clinical course, treatment and outcome. J Neurol Neurosurg Psychiatry 77:933–937PubMedPubMedCentral
28.
go back to reference Partridge JS, Harari D, Martin FC, Dhesi JK (2014) The impact of pre-operative comprehensive geriatric assessment on postoperative outcomes in older patients undergoing scheduled surgery: a systematic review. Anaesthesia 69(Suppl 1):8–16PubMed Partridge JS, Harari D, Martin FC, Dhesi JK (2014) The impact of pre-operative comprehensive geriatric assessment on postoperative outcomes in older patients undergoing scheduled surgery: a systematic review. Anaesthesia 69(Suppl 1):8–16PubMed
29.
go back to reference Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, Mitnitski A (2005) A global clinical measure of fitness and frailty in elderly people. CMAJ Canad Med Assoc J journal de l'Association medicale canadienne 173:489–495 Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, Mitnitski A (2005) A global clinical measure of fitness and frailty in elderly people. CMAJ Canad Med Assoc J journal de l'Association medicale canadienne 173:489–495
30.
go back to reference Ryttlefors M, Enblad P, Kerr RSC, Molyneux A (2008) International subarachnoid aneurysm trial of neurosurgical clipping versus endovascular coiling. Stroke 39:2720–2726PubMed Ryttlefors M, Enblad P, Kerr RSC, Molyneux A (2008) International subarachnoid aneurysm trial of neurosurgical clipping versus endovascular coiling. Stroke 39:2720–2726PubMed
31.
go back to reference Santarius T, Kirkpatrick PJ, Ganesan D, Chia HL, Jalloh I, Smielewski P, Richards HK, Marcus H, Parker RA, Price SJ, Kirollos RW, Pickard JD, Hutchinson PJ (2009) Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial. Lancet 374:1067–1073PubMed Santarius T, Kirkpatrick PJ, Ganesan D, Chia HL, Jalloh I, Smielewski P, Richards HK, Marcus H, Parker RA, Price SJ, Kirollos RW, Pickard JD, Hutchinson PJ (2009) Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial. Lancet 374:1067–1073PubMed
32.
go back to reference Scaggiante J, Zhang X, Mocco J, Kellner CP (2018) Minimally invasive surgery for intracerebral hemorrhage. Stroke 49:2612–2620PubMed Scaggiante J, Zhang X, Mocco J, Kellner CP (2018) Minimally invasive surgery for intracerebral hemorrhage. Stroke 49:2612–2620PubMed
33.
go back to reference Scholler K, Massmann M, Markl G, Kunz M, Fesl G, Bruckmann H, Pfefferkorn T, Tonn JC, Schichor C (2013) Aneurysmal subarachnoid hemorrhage in elderly patients: long-term outcome and prognostic factors in an interdisciplinary treatment approach. J Neurol 260:1052–1060PubMed Scholler K, Massmann M, Markl G, Kunz M, Fesl G, Bruckmann H, Pfefferkorn T, Tonn JC, Schichor C (2013) Aneurysmal subarachnoid hemorrhage in elderly patients: long-term outcome and prognostic factors in an interdisciplinary treatment approach. J Neurol 260:1052–1060PubMed
34.
go back to reference Shimizu K, Sadatomo T, Hara T, Onishi S, Yuki K, Kurisu K (2018) Importance of frailty evaluation in the prediction of the prognosis of patients with chronic subdural hematoma. Geriatrics Gerontol Int 18:1173–1176 Shimizu K, Sadatomo T, Hara T, Onishi S, Yuki K, Kurisu K (2018) Importance of frailty evaluation in the prediction of the prognosis of patients with chronic subdural hematoma. Geriatrics Gerontol Int 18:1173–1176
35.
go back to reference Stein M, Misselwitz B, Hamann Gerhard F, Scharbrodt W, Schummer Dorothee I, Oertel Matthias F (2012) Intracerebral hemorrhage in the Very Old. Stroke 43:1126–1128PubMed Stein M, Misselwitz B, Hamann Gerhard F, Scharbrodt W, Schummer Dorothee I, Oertel Matthias F (2012) Intracerebral hemorrhage in the Very Old. Stroke 43:1126–1128PubMed
36.
go back to reference Sturiale CL, Brinjikji W, Murad MH, Lanzino G (2013) Endovascular treatment of intracranial aneurysms in elderly patients. Stroke 44:1897–1902PubMed Sturiale CL, Brinjikji W, Murad MH, Lanzino G (2013) Endovascular treatment of intracranial aneurysms in elderly patients. Stroke 44:1897–1902PubMed
37.
go back to reference Tang Y, Yin F, Fu D, Gao X, Lv Z, Li X (2018) Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis. BMC Neurol 18:136PubMedPubMedCentral Tang Y, Yin F, Fu D, Gao X, Lv Z, Li X (2018) Efficacy and safety of minimal invasive surgery treatment in hypertensive intracerebral hemorrhage: a systematic review and meta-analysis. BMC Neurol 18:136PubMedPubMedCentral
39.
go back to reference Tomlinson SB, Piper K, Kimmell KT, Vates GE (2017) Preoperative frailty score for 30-day morbidity and mortality after cranial neurosurgery. World Neurosurg 107:959–965PubMed Tomlinson SB, Piper K, Kimmell KT, Vates GE (2017) Preoperative frailty score for 30-day morbidity and mortality after cranial neurosurgery. World Neurosurg 107:959–965PubMed
40.
go back to reference Wahl TS, Graham LA, Hawn MT, Richman J, Hollis RH, Jones CE, Copeland LA, Burns EA, Itani KM, Morris MS (2017) Association of the modified frailty index with 30-day surgical readmission. JAMA Surg 152:749–757PubMedPubMedCentral Wahl TS, Graham LA, Hawn MT, Richman J, Hollis RH, Jones CE, Copeland LA, Burns EA, Itani KM, Morris MS (2017) Association of the modified frailty index with 30-day surgical readmission. JAMA Surg 152:749–757PubMedPubMedCentral
41.
go back to reference Whitehouse KJ, Jeyaretna DS, Enki DG, Whitfield PC (2016) Head injury in the elderly: what are the outcomes of neurosurgical care? World Neurosurg 94:493–500PubMed Whitehouse KJ, Jeyaretna DS, Enki DG, Whitfield PC (2016) Head injury in the elderly: what are the outcomes of neurosurgical care? World Neurosurg 94:493–500PubMed
42.
go back to reference Whitehouse KJ, Jeyaretna DS, Wright A, Whitfield PC (2016) Neurosurgical care in the elderly: increasing demands necessitate future healthcare planning. World Neurosurg 87:446–454PubMed Whitehouse KJ, Jeyaretna DS, Wright A, Whitfield PC (2016) Neurosurgical care in the elderly: increasing demands necessitate future healthcare planning. World Neurosurg 87:446–454PubMed
43.
go back to reference Wiebers DO (2003) Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. The Lancet 362:103–110 Wiebers DO (2003) Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. The Lancet 362:103–110
44.
go back to reference Won S-Y, Dubinski D, Brawanski N, Strzelczyk A, Seifert V, Freiman TM, Konczalla J (2017) Significant increase in acute subdural hematoma in octo- and nonagenarians: surgical treatment, functional outcome, and predictors in this patient cohort. Neurosurg Focus 43:E10PubMed Won S-Y, Dubinski D, Brawanski N, Strzelczyk A, Seifert V, Freiman TM, Konczalla J (2017) Significant increase in acute subdural hematoma in octo- and nonagenarians: surgical treatment, functional outcome, and predictors in this patient cohort. Neurosurg Focus 43:E10PubMed
45.
go back to reference Won S-Y, Dubinski D, Bruder M, Cattani A, Seifert V, Konczalla J (2017) Acute subdural hematoma in patients on oral anticoagulant therapy: management and outcome. Neurosurg Focus 43:E12PubMed Won S-Y, Dubinski D, Bruder M, Cattani A, Seifert V, Konczalla J (2017) Acute subdural hematoma in patients on oral anticoagulant therapy: management and outcome. Neurosurg Focus 43:E12PubMed
46.
go back to reference Youngerman BE, Neugut AI, Yang J, Hershman DL, Wright JD, Bruce JN (2018) The modified frailty index and 30-day adverse events in oncologic neurosurgery. J Neurooncol 136:197–206PubMed Youngerman BE, Neugut AI, Yang J, Hershman DL, Wright JD, Bruce JN (2018) The modified frailty index and 30-day adverse events in oncologic neurosurgery. J Neurooncol 136:197–206PubMed
47.
go back to reference Yue Q, Liu Y, Leng B, Xu B, Gu Y, Chen L, Zhu W, Mao Y (2016) A prognostic model for early post-treatment outcome of elderly patients with aneurysmal subarachnoid hemorrhage. World Neurosurg 95:253–261PubMed Yue Q, Liu Y, Leng B, Xu B, Gu Y, Chen L, Zhu W, Mao Y (2016) A prognostic model for early post-treatment outcome of elderly patients with aneurysmal subarachnoid hemorrhage. World Neurosurg 95:253–261PubMed
Metadata
Title
The changing face of neurosurgery for the older person
Authors
Ellie Edlmann
Peter C. Whitfield
Publication date
01-08-2020
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology / Issue 8/2020
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-020-09854-9

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