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25-07-2022 | Subacute Granulomatous Thyroiditis | Viewpoint

Thyroid function changes and COVID-19 severity: egg or chicken?

Authors: Wenjie Chen, Jianyong Lei, Zhihui Li

Published in: Endocrine | Issue 3/2022

Abstract

The novel coronavirus disease 2019 (COVID-19) produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious infectious disease. In addition to typical flu-like symptoms, COVID-19 can also cause extrapulmonary spread and systemic inflammation, potentially causing multiorgan dysfunction, including thyroid dysfunction. Thyroid function changes in patients with COVID-19 have been widely reported, but the results are inconsistent. Based on available data, SARS-CoV-2 infection can lead to changes in thyroid function, and the degree of thyroid function changes was positively correlated with the severity of COVID-19, which involved multiple potential mechanisms. In contrast, current evidence was insufficient to prove that thyroid function changes could induce the progression of COVID-19 clinical deterioration.

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Title: Thyroid function changes and COVID-19 severity: egg or chicken?
Authors: Wenjie Chen
Jianyong Lei
Zhihui Li
Publication date: 25-07-2022
Publisher: Springer US
Keywords: Subacute Granulomatous Thyroiditis
SARS-CoV-2
COVID-19
Published in: Endocrine / Issue 3/2022
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-022-03129-1

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