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Diabetologia

Issue 6/2020

Content (20 Articles)

Open Access Obesity Review

Diabetes through a 3D lens: organoid models

Anastasia Tsakmaki, Patricia Fonseca Pedro, Gavin A. Bewick

Open Access Diabetic Retinopathy Article

Prediction models for development of retinopathy in people with type 2 diabetes: systematic review and external validation in a Dutch primary care setting

Amber A. van der Heijden, Giel Nijpels, Fariza Badloe, Heidi L. Lovejoy, Linda M. Peelen, Talitha L. Feenstra, Karel G. M. Moons, Roderick C. Slieker, Ron M. C. Herings, Petra J. M. Elders, Joline W. Beulens

Open Access Gestational Diabetes Article

A core outcome set for studies of gestational diabetes mellitus prevention and treatment

Aoife M. Egan, Delia Bogdanet, Tomás P. Griffin, Oratile Kgosidialwa, Mila Cervar-Zivkovic, Eugene Dempsey, John Allotey, Fernanda Alvarado, Cheril Clarson, Shamil D. Cooray, Harold W. de Valk, Sander Galjaard, Mary R. Loeken, Michael J. A. Maresh, Angela Napoli, Paula M. O’Shea, Ewa Wender-Ozegowska, Mireille N. M. van Poppel, Shakila Thangaratinam, Caroline Crowther, Linda M. Biesty, Declan Devane, Fidelma P. Dunne

Open Access Glimepiride Article

Effects of ertugliflozin on renal function over 104 weeks of treatment: a post hoc analysis of two randomised controlled trials

David Z. I. Cherney, Hiddo J. L. Heerspink, Robert Frederich, Mario Maldonado, Jie Liu, Annpey Pong, Zhi J. Xu, Shrita Patel, Anne Hickman, James P. Mancuso, Ira Gantz, Steven G. Terra

Open Access Type 2 Diabetes Article

Early puberty and risk for type 2 diabetes in men

Claes Ohlsson, Maria Bygdell, Maria Nethander, Jenny M. Kindblom

Impact of glucose on risk of dementia: Mendelian randomisation studies in 115,875 individuals

Marianne Benn, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Ruth Frikke-Schmidt

Effect of maternal smoking during pregnancy on childhood type 1 diabetes: a whole-of-population study

Mumtaz Begum, Rhiannon M. Pilkington, Catherine R. Chittleborough, John W. Lynch, Megan Penno, Lisa G. Smithers

Open Access Type 1 Diabetes Article

Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype

Stephanie J. Hanna, Wendy E. Powell, Anna E. Long, Emma J. S. Robinson, Joanne Davies, Clare Megson, Alexandra Howell, Taz J. Jones, Kristin Ladell, David A. Price, Colin M. Dayan, Alistair J. K. Williams, Kathleen M. Gillespie, F. Susan Wong

Open Access Type 1 Diabetes Article

GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells

Sefina Arif, Iria Gomez-Tourino, Yogesh Kamra, Irma Pujol-Autonell, Emily Hanton, Timothy Tree, Daisy Melandri, Caroline Hull, Diane K. Wherrett, Craig Beam, Bart O. Roep, Anna Lorenc, Mark Peakman

Open Access Obesity Article

Associations of birthweight and history of childhood obesity with beta cell mass in Japanese adults

Hironobu Sasaki, Yoshifumi Saisho, Jun Inaishi, Yuusuke Watanabe, Tami Tsuchiya, Masayoshi Makio, Midori Sato, Minoru Kitago, Taketo Yamada, Hiroshi Itoh

Open Access Insulins Article

One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspension

Lena Bilet, Esther Phielix, Tineke van de Weijer, Anne Gemmink, Madeleen Bosma, Esther Moonen-Kornips, Johanna A. Jorgensen, Gert Schaart, Dongyan Zhang, Kenneth Meijer, Maria Hopman, Matthijs K. C. Hesselink, D. Margriet Ouwens, Gerald I. Shulman, Vera B. Schrauwen-Hinderling, Patrick Schrauwen

Open Access Bariatric Surgery Article

Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto–Kakizaki rats improves glucose homeostasis through enhanced FXR signalling

Noémie Péan, Aurelie Le Lay, Francois Brial, Jessica Wasserscheid, Claude Rouch, Mylène Vincent, Antonis Myridakis, Lyamine Hedjazi, Marc-Emmanuel Dumas, Elin Grundberg, Mark Lathrop, Christophe Magnan, Ken Dewar, Dominique Gauguier

Open Access Insulins Article

Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity

Sigrid Jall, Meri De Angelis, Anne-Marie Lundsgaard, Andreas M. Fritzen, Trine S. Nicolaisen, Anders B. Klein, Aaron Novikoff, Stephan Sachs, Erik A. Richter, Bente Kiens, Karl-Werner Schramm, Matthias H. Tschöp, Kerstin Stemmer, Christoffer Clemmensen, Timo D. Müller, Maximilian Kleinert

Open Access Type 2 Diabetes Article

Lipoprotein(a) plasma levels are not associated with incident microvascular complications in type 2 diabetes mellitus

Sunny S. Singh, Mardin Rashid, Aloysius G. Lieverse, Florian Kronenberg, Claudia Lamina, Monique T. Mulder, Yolanda B. de Rijke, Eric J. G. Sijbrands, Mandy van Hoek

Open Access Insulins Article

Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis

Pia Leete, Richard A. Oram, Timothy J. McDonald, Beverley M. Shields, Clemens Ziller, Bart O. Roep, Timothy I. Tree, Kashyap Patel, Suzy Hammersley, Robert Bolt, Anita V. Hill, Andrew T. Hattersley, Sarah J. Richardson, Noel G. Morgan

Open Access Sulfonylurea Article

Weight change and sulfonylurea therapy are related to 3 year change in microvascular function in people with type 2 diabetes

Francesco Casanova, Kim M. Gooding, Angela C. Shore, Damilola D. Adingupu, David Mawson, Claire Ball, Christine Anning, Kunihiko Aizawa, Philip E. Gates, W. David Strain

The role of vitamin D in the aetiology of type 1 diabetes. Reply to Korsgren O [letter]

Maija E. Miettinen, Sari Niinistö, Jarno Honkanen, Iris Erlund, Mikael Knip, Suvi M. Virtanen

Live Webinar | 27-06-2024 | 18:00 (CEST)

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine