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Diabetologia

Issue 3/2019

Content (22 Articles)

Review

Neoepitopes: a new take on beta cell autoimmunity in type 1 diabetes

Stuart I. Mannering, Anthony R. Di Carluccio, Colleen M. Elso

Commentary

What do we know about the trends in incidence of childhood-onset type 1 diabetes?

Jean M. Lawrence, Elizabeth J. Mayer-Davis

Open Access Article

Randomised, phase 1, dose-finding study of MEDI4166, a PCSK9 antibody and GLP-1 analogue fusion molecule, in overweight or obese patients with type 2 diabetes mellitus

Meena Jain, Glenn Carlson, William Cook, Linda Morrow, Marcella Petrone, Nicholas E. White, Tao Wang, Jacqueline Naylor, Philip Ambery, Charles Lee, Boaz Hirshberg

Insulins Article

Breastfeeding at night is rarely followed by hypoglycaemia in women with type 1 diabetes using carbohydrate counting and flexible insulin therapy

Lene Ringholm, Ann B. Roskjær, Susanne Engberg, Henrik U. Andersen, Anna L. Secher, Peter Damm, Elisabeth R. Mathiesen

Open Access Article

Tetraspanin 7 autoantibodies predict progressive decline of beta cell function in individuals with LADA

Xiajie Shi, Gan Huang, Yanfei Wang, Zhenqi Liu, Chao Deng, Xia Li, Peilin Zheng, Zhiguang Zhou

Open Access Article

Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989–2013: a multicentre prospective registration study

Christopher C. Patterson, Valma Harjutsalo, Joachim Rosenbauer, Andreas Neu, Ondrej Cinek, Torild Skrivarhaug, Birgit Rami-Merhar, Gyula Soltesz, Jannet Svensson, Roger C. Parslow, Conxa Castell, Eugen J. Schoenle, Polly J. Bingley, Gisela Dahlquist, Przemysława K. Jarosz-Chobot, Dalė Marčiulionytė, Edna F. Roche, Ulrike Rothe, Natasa Bratina, Constantin Ionescu-Tirgoviste, Ilse Weets, Mirjana Kocova, Valentino Cherubini, Natasa Rojnic Putarek, Carine E. deBeaufort, Mira Samardzic, Anders Green

Open Access Myocardial Infarction Article

Trends in incidence and case fatality of acute myocardial infarction, angina and coronary revascularisation in people with and without type 2 diabetes in Scotland between 2006 and 2015

Stephanie H. Read, Colin M. Fischbacher, Helen M. Colhoun, Danijela Gasevic, Joannes J. Kerssens, David A. McAllister, Naveed Sattar, Sarah H. Wild

Stroke Article

Ideal cardiovascular health, glycaemic status and incident type 2 diabetes mellitus: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study

Joshua J. Joseph, Aleena Bennett, Justin B. Echouffo Tcheugui, Valery S. Effoe, James B. Odei, Bertha Hidalgo, Akilah Dulin, Monika M. Safford, Doyle M. Cummings, Mary Cushman, April P. Carson

Article

Type 2 diabetes mellitus, brain atrophy and cognitive decline in older people: a longitudinal study

Michele L. Callisaya, Richard Beare, Chris Moran, Thanh Phan, Wei Wang, Velandai K. Srikanth

Article

DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway

Reinaldo S. Dos Santos, Laura Marroqui, Teresa Velayos, Ane Olazagoitia-Garmendia, Amaia Jauregi-Miguel, Ainara Castellanos-Rubio, Decio L. Eizirik, Luis Castaño, Izortze Santin

Article

Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries

Rachel Kadakia, Michael Nodzenski, Octavious Talbot, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Robert D. Stevens, Olga R. Ilkayeva, Sara K. O’Neal, Lynn P. Lowe, Boyd E. Metzger, Christopher B. Newgard, Denise M. Scholtens, William L. Lowe Jr

Reduced skeletal-muscle perfusion and impaired ATP release during hypoxia and exercise in individuals with type 2 diabetes

Martin B. Groen, Trine A. Knudsen, Stine H. Finsen, Bente K. Pedersen, Ylva Hellsten, Stefan P. Mortensen

Article

Substrate metabolism, hormone and cytokine levels and adipose tissue signalling in individuals with type 1 diabetes after insulin withdrawal and subsequent insulin therapy to model the initiating steps of ketoacidosis

Thomas S. Voss, Mikkel H. Vendelbo, Ulla Kampmann, Steen B. Pedersen, Thomas S. Nielsen, Mogens Johannsen, Mads V. Svart, Niels Jessen, Niels Møller

Article

Anti-fumarase antibody promotes the dropout of photoreceptor inner and outer segments in diabetic macular oedema

Shin Yoshitake, Tomoaki Murakami, Kiyoshi Suzuma, Tatsuya Yoshitake, Akihito Uji, Satoshi Morooka, Yoko Dodo, Masahiro Fujimoto, Yang Shan, Patrice E. Fort, Shinji Ito, Akitaka Tsujikawa, Nagahisa Yoshimura

lncRNA H19 prevents endothelial–mesenchymal transition in diabetic retinopathy

Anu A. Thomas, Saumik Biswas, Biao Feng, Shali Chen, John Gonder, Subrata Chakrabarti

Loss of X-box binding protein 1 in Müller cells augments retinal inflammation in a mouse model of diabetes

Jing Yang, Chen Chen, Todd McLaughlin, Yaqin Wang, Yun-Zheng Le, Joshua J. Wang, Sarah X. Zhang

Open Access Research Letter

One hour post-load plasma glucose and 3 year risk of worsening fasting and 2 hour glucose tolerance in the RISC cohort

Melania Manco, Andrea Mari, John Petrie, Geltrude Mingrone, Beverley Balkau

Correction

Correction to: Nuts as a replacement for carbohydrates in the diabetic diet: a reanalysis of a randomised controlled trial

David J. A. Jenkins, Cyril W. C. Kendall, Benoît Lamarche, Monica S. Banach, Korbua Srichaikul, Edward Vidgen, Sandy Mitchell, Tina Parker, Stephanie Nishi, Balachandran Bashyam, Russell J. de Souza, Christopher Ireland, Sathish C. Pichika, Joseph Beyene, John L. Sievenpiper, Robert G. Josse

Correction

Correction to: Identification of an intracellular metabolic signature impairing beta cell function in the rat beta cell line INS-1E and human islets

I. Goehring, N. S. Sauter, G. Catchpole, A. Assmann, L. Shu, K. S. Zien, M. Moehlig, A. F. H. Pfeiffer, J. Oberholzer, L. Willmitzer, J. Spranger, K. Maedler

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.