Issue 4/2016
Content (8 Articles)
Leading Article
The First-in-Class Potassium-Competitive Acid Blocker, Vonoprazan Fumarate: Pharmacokinetic and Pharmacodynamic Considerations
Hirotoshi Echizen
Open Access
Review Article
Impact of New Genomic Technologies on Understanding Adverse Drug Reactions
Simran D. S. Maggo, Ruth L. Savage, Martin A. Kennedy
Erratum
Erratum to: Impact of New Genomic Technologies on Understanding Adverse Drug Reactions
Simran D. S. Maggo, Ruth L. Savage, Martin A. Kennedy
Systematic Review
Therapeutic Concentrations of Metformin: A Systematic Review
Farshad Kajbaf, Marc E. De Broe, Jean-Daniel Lalau
Original Research Article
Population Pharmacokinetic Analysis of Lanreotide Autogel®/Depot in the Treatment of Neuroendocrine Tumors: Pooled Analysis of Four Clinical Trials
Núria Buil-Bruna, María Jesús Garrido, Marion Dehez, Amandine Manon, Thi Xuan Quyen Nguyen, Edda L. Gomez-Panzani, Iñaki F. Trocóniz
Original Research Article
Predicting the Effect of CYP3A Inducers on the Pharmacokinetics of Substrate Drugs Using Physiologically Based Pharmacokinetic (PBPK) Modeling: An Analysis of PBPK Submissions to the US FDA
Christian Wagner, Yuzhuo Pan, Vicky Hsu, Vikram Sinha, Ping Zhao
Original Research Article
Pharmacokinetics, Efficacy, and Safety of the Preservative-free Fixed Combination of Tafluprost 0.0015 % and Timolol 0.5 % in Healthy Volunteers: A Phase I Comparison vs. the Corresponding Preservative-free Monotherapies
Kai Kaarniranta, Kirsi Ikäheimo, Eliisa Mannermaa, Auli Ropo
Original Research Article
The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers
Kari M. Morrissey, Sophie L. Stocker, Eugene C. Chen, Richard A. Castro, Claire M. Brett, Kathleen M. Giacomini