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Breast Cancer Research and Treatment

Issue 2/2015

Content (22 Articles)

Review

BI-RADS update for breast cancer caregivers

Emily L. Sedgwick, Lilian Ebuoma, Anthony Hamame, Kanchan Phalak, Lorell Ruiz-Flores, Tamara Ortiz-Perez, Karla A. Sepulveda

Preclinical study

Cancer-mediated adipose reversion promotes cancer cell migration via IL-6 and MCP-1

Kaoru Fujisaki, Hiroshi Fujimoto, Takafumi Sangai, Takeshi Nagashima, Masahiro Sakakibara, Nobumitsu Shiina, Masayuki Kuroda, Yasuyuki Aoyagi, Masaru Miyazaki

Preclinical Study

Inhibition of BET proteins impairs estrogen-mediated growth and transcription in breast cancers by pausing RNA polymerase advancement

Surojeet Sengupta, Michael C. Biarnes, Robert Clarke, V. Craig Jordan

Preclinical Study

Predictive role of HER2/neu, topoisomerase-II-alpha, and tissue inhibitor of metalloproteinases (TIMP-1) for response to adjuvant taxane-based chemotherapy in patients with intermediate-risk breast cancer: results from the WSG-AGO EC-Doc trial

Ramona Erber, Oleg Gluz, Nils Brünner, Hans Heinrich Kreipe, Enrico Pelz, Ronald Kates, Annette Bartels, Jens Huober, Svjetlana Mohrmann, Zehra Moustafa, Cornelia Liedtke, Volker Möbus, Doris Augustin, Christoph Thomssen, Fritz Jänicke, Marion Kiechle, Walther Kuhn, Ulrike Nitz, Nadia Harbeck, Arndt Hartmann

Open Access Preclinical study

Splicing analysis of 14 BRCA1 missense variants classifies nine variants as pathogenic

Lise B. Ahlborn, Mette Dandanell, Ane Y. Steffensen, Lars Jønson, Finn C. Nielsen, Thomas v. O. Hansen

Preclinical Study

PIK3CA mutations in serum DNA are predictive of recurrence in primary breast cancer patients

Chiya Oshiro, Naofumi Kagara, Yasuto Naoi, Masafumi Shimoda, Atsushi Shimomura, Naomi Maruyama, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi

Preclinical Study

The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells

Wei Bin Fang, Min Yao, Iman Jokar, Nabil Alhakamy, Cory Berkland, Jin Chen, Dana Brantley-Sieders, Nikki Cheng

Preclinical Study

Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer

Callie R. Merry, Sarah McMahon, Cheryl L. Thompson, Kristy L. S. Miskimen, Lyndsay N. Harris, Ahmad M. Khalil

Preclinical study

Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer

Rezvan Abduljabbar, Ola H. Negm, Chun-Fui Lai, Dena A. Jerjees, Methaq Al-Kaabi, Mohamed R. Hamed, Patrick J. Tighe, Lakjaya Buluwela, Abhik Mukherjee, Andrew R. Green, Simak Ali, Emad A. Rakha, Ian O. Ellis

Preclinical Study

Pnck overexpression in HER-2 gene-amplified breast cancer causes Trastuzumab resistance through a paradoxical PTEN-mediated process

Tushar B. Deb, Annie H. Zuo, Robert J. Barndt, Surojeet Sengupta, Radmila Jankovic, Michael D. Johnson

Open Access Preclinical study

High tumor budding stratifies breast cancer with metastatic properties

Bodour Salhia, Mafalda Trippel, Katrin Pfaltz, Nikola Cihoric, André Grogg, Claudia Lädrach, Inti Zlobec, Coya Tapia

Clinical trial

A nomogram based on mammary ductoscopic indicators for evaluating the risk of breast cancer in intraductal neoplasms with nipple discharge

Zhen-Qiang Lian, Qi Wang, An-Qin Zhang, Jiang-Yu Zhang, Xiao-Rong Han, Hai-Yun Yu, Si-Mei Xie

Clinical Trial

The impact of breast cancer-related lymphedema on the ability to perform upper extremity activities of daily living

Jean A. O’Toole, Chantal M. Ferguson, Meyha N. Swaroop, Nora Horick, Melissa N. Skolny, Cheryl L. Brunelle, Cynthia L. Miller, Lauren S. Jammallo, Michelle C. Specht, Alphonse G. Taghian

Epidemiology

The prevalence of BRCA1 and BRCA2 mutations among young Mexican women with triple-negative breast cancer

C. Villarreal-Garza, J. N. Weitzel, M. Llacuachaqui, E. Sifuentes, M. C. Magallanes-Hoyos, L. Gallardo, R. M. Alvarez-Gómez, J. Herzog, D. Castillo, R. Royer, Mohammad Akbari, F. Lara-Medina, L. A. Herrera, A. Mohar, S. A. Narod

Epidemiology

Smoking and survival in female breast cancer patients

Alicia Padron-Monedero, Stacey L. Tannenbaum, Tulay Koru-Sengul, Feng Miao, Damien Hansra, David J. Lee, Margaret M. Byrne

Epidemiology

Breast cancer incidence after hormonal treatments for infertility: systematic review and meta-analysis of population-based studies

Alessandra Gennari, Mauro Costa, Matteo Puntoni, Laura Paleari, Andrea De Censi, Maria Pia Sormani, Nicoletta Provinciali, Paolo Bruzzi

Epidemiology

A comparison between different prediction models for invasive breast cancer occurrence in the French E3N cohort

Laureen Dartois, Émilien Gauthier, Julia Heitzmann, Laura Baglietto, Stefan Michiels, Sylvie Mesrine, Marie-Christine Boutron-Ruault, Suzette Delaloge, Stéphane Ragusa, Françoise Clavel-Chapelon, Guy Fagherazzi

Epidemiology

The association between glucose-lowering drug use and mortality among breast cancer patients with type 2 diabetes

Pauline A. J. Vissers, Chris R. Cardwell, Lonneke V. van de Poll-Franse, Ian S. Young, Frans Pouwer, Liam J. Murray

Epidemiology

Elevated risks of subsequent endometrial cancer development among breast cancer survivors with different hormone receptor status: a SEER analysis

Jieqiong Liu, Wen Jiang, Kai Mao, Yi An, Fengxi Su, Betty Y. S. Kim, Qiang Liu, Lisa K. Jacobs

Epidemiology

Integrated analysis of DNA methylation, immunohistochemistry and mRNA expression, data identifies a methylation expression index (MEI) robustly associated with survival of ER-positive breast cancer patients

Jonine D. Figueroa, Howard Yang, Montserrat Garcia-Closas, Sean Davis, Paul Meltzer, Jolanta Lissowska, Hisani N. Horne, Mark E. Sherman, Maxwell Lee

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine