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Breast Cancer Research and Treatment

Issue 2/2012

Content (41 Articles)

Review

The role of antiresorptive therapies in improving patient care in early and metastatic breast cancer

Dulcinea Candelaria-Quintana, Zoneddy R. Dayao, Melanie E. Royce

Preclinical study

Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH

Simon A. Joosse, Kim I. M. Brandwijk, Peter Devilee, Jelle Wesseling, Frans B. L. Hogervorst, Senno Verhoef, Petra M. Nederlof

Preclinical study

KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer

Muralidharan Anbalagan, Latonya Carrier, Seth Glodowski, David Hangauer, Bin Shan, Brian G. Rowan

Preclinical study

Estrogen receptor-α and sex steroid hormones regulate Toll-like receptor-9 expression and invasive function in human breast cancer cells

Jouko Sandholm, Joonas H. Kauppila, Christine Pressey, Johanna Tuomela, Arja Jukkola-Vuorinen, Markku Vaarala, Martin R. Johnson, Kevin W. Harris, Katri S. Selander

Preclinical Study

Prevalence and characterization of BRCA1 and BRCA2 germline mutations in Chinese women with familial breast cancer

Juan Zhang, Renguang Pei, Zhiyuan Pang, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Yuntao Xie

Preclinical Study

Increased risk for distant metastasis in patients with familial early-stage breast cancer and high EZH2 expression

Sharon Hensley Alford, Katherine Toy, Sofia D. Merajver, Celina G. Kleer

Preclinical Study

Gene expression profiling assigns CHEK2 1100delC breast cancers to the luminal intrinsic subtypes

Jord H. A. Nagel, Justine K. Peeters, Marcel Smid, Anieta M. Sieuwerts, Marijke Wasielewski, Vanja de Weerd, Anita M. A. C. Trapman-Jansen, Ans van den Ouweland, Hennie Brüggenwirth, Wilfred F. J. van IJcken, Jan G. M. Klijn, Peter J. van der Spek, John A. Foekens, John W. M. Martens, Mieke Schutte, Hanne Meijers-Heijboer

Preclinical Study

The peptide-hormone glucagon-like peptide-1 activates cAMP and inhibits growth of breast cancer cells

Hagai Ligumsky, Ido Wolf, Shira Israeli, Michal Haimsohn, Sarah Ferber, Avraham Karasik, Bella Kaufman, Tami Rubinek

Preclinical Study

In situ detection of HER2:HER2 and HER2:HER3 protein–protein interactions demonstrates prognostic significance in early breast cancer

Melanie Spears, Karen J. Taylor, Alison F. Munro, Carrie A. Cunningham, Elizabeth A. Mallon, Chris J. Twelves, David A. Cameron, Jeremy Thomas, John M. S. Bartlett

Preclinical Study

Bone metastasis in a novel breast cancer mouse model containing human breast and human bone

Tian-Song Xia, Guo-Zhu Wang, Qiang Ding, Xiao-An Liu, Wen-Bin Zhou, Yi-Fen Zhang, Xiao-Ming Zha, Qing Du, Xiao-Jian Ni, Jue Wang, Su-Yu Miao, Shui Wang

Preclinical study

Pilot and feasibility study: prospective proteomic profiling of mammary epithelial cells from high-risk women provides evidence of activation of pro-survival pathways

Catherine Ibarra-Drendall, Michelle M. Troch, William T. Barry, Gloria Broadwater, Emanuel F. Petricoin III, Julia Wulfkuhle, Lance A. Liotta, Siya Lem, Joseph C. Baker Jr., Anne C. Ford, Lee G. Wilke, Carola Zalles, Nicole M. Kuderer, Abigail W. Hoffman, Melanie Shivraj, Priya Mehta, Jamila Williams, Nora Tolbert, Laurie W. Lee, Patrick G. Pilie, Dihua Yu, Victoria L. Seewaldt

Preclinical Study

A prognostic model for lymph node-negative breast cancer patients based on the integration of proliferation and immunity

Ensel Oh, Yoon-La Choi, Taesung Park, Seungyeoun Lee, Seok Jin Nam, Young Kee Shin

Preclinical study

ER, HER2, and TOP2A expression in primary tumor, synchronous axillary nodes, and asynchronous metastases in breast cancer

Jeanette Dupont Jensen, Ann Knoop, Marianne Ewertz, Anne-Vibeke Laenkholm

Open Access Preclinical Study

Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse

J. Chuck Harrell, Aleix Prat, Joel S. Parker, Cheng Fan, Xiaping He, Lisa Carey, Carey Anders, Matthew Ewend, Charles M. Perou

Preclinical Study

LMTK3 expression in breast cancer: association with tumor phenotype and clinical outcome

Justin Stebbing, Aleksandra Filipovic, Ian O. Ellis, Andrew R. Green, Tanya Rapoz D’Silva, Heinz-Josef Lenz, R. Charles Coombes, Tingting Wang, Soo-Chin Lee, Georgios Giamas

Preclinical Study

The prognostic significance of B lymphocytes in invasive carcinoma of the breast

S. M. A. Mahmoud, A. H. S. Lee, E. C. Paish, R. D. Macmillan, I. O. Ellis, A. R. Green

Preclinical study

The anatomy of fluid-yielding ducts in breast cancer

Dominique Twelves, Ashutosh Nerurkar, Peter Osin, Ann Ward, Clare M. Isacke, Gerald P. H. Gui

Preclinical Study

Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer

Cecilia L. Speyer, Jennifer S. Smith, Malathi Banda, John A. DeVries, Tassia Mekani, David H. Gorski

Preclinical Study

Targeting low molecular weight cyclin E (LMW-E) in breast cancer

Angela Nanos-Webb, Natalie A. Jabbour, Asha S. Multani, Hannah Wingate, Nassima Oumata, Hervé Galons, Benoît Joseph, Laurent Meijer, Kelly K. Hunt, Khandan Keyomarsi

Clinical trial

Phase II trial of preoperative paclitaxel, gemcitabine, and trastuzumab combination therapy in HER2 positive stage II/III breast cancer: The Korean Cancer Study Group BR 07-01

Seock-Ah Im, Keun Seok Lee, Jungsil Ro, Eun Sook Lee, Youngmee Kwon, Jin-Hee Ahn, Jin Seok Ahn, Jee Hyun Kim, Han Sung Kang, Kyung Hwan Shin, Dong-Young Noh, In-Ae Park, Sung-Bae Kim, Young Hyuck Im, Sung Whan Ha

Clinical Trial

Comparison of two nomograms to predict pathologic complete responses to neoadjuvant chemotherapy for breast cancer: evidence that HER2-positive tumors need specific predictors

Albane Frati, Elisabeth Chereau, Charles Coutant, Corinne Bezu, Martine Antoine, Jocelyne Chopier, Emile Daraï, Serge Uzan, Joseph Gligorov, Roman Rouzier

Clinical trial

Postoperative dose-dense sequential versus concomitant administration of epirubicin and paclitaxel in patients with node-positive breast cancer: 5-year results of the Hellenic Cooperative Oncology Group HE 10/00 phase III Trial

Helen Gogas, Urania Dafni, Maria Karina, Christos Papadimitriou, Anna Batistatou, Mattheos Bobos, Haralabos P. Kalofonos, Anastasia G. Eleftheraki, Eleni Timotheadou, Dimitrios Bafaloukos, Christos Christodoulou, Christos Markopoulos, Evangelos Briasoulis, Pavlos Papakostas, Epaminontas Samantas, Paris Kosmidis, George P. Stathopoulos, Charisios Karanikiotis, Dimitrios Pectasides, Meletios A. Dimopoulos, George Fountzilas

Clinical Trial

Absence of ectopic epithelial inclusions in 3,904 axillary lymph nodes examined in sentinel technique

Sonja Iken, Marcus Schmidt, Claudia Braun, Antonietta Valentino, Hans-Anton Lehr, Stephan C. Schaefer

Clinical trial

Outcomes of a weight loss intervention among rural breast cancer survivors

Christie A. Befort, Jennifer R. Klemp, Heather L. Austin, Michael G. Perri, Kathryn H. Schmitz, Debra K. Sullivan, Carol J. Fabian

Epidemiology

Cadherin–catenin complex dissociation in lobular neoplasia of the breast

Mary Morrogh, Victor P. Andrade, Dilip Giri, Rita A. Sakr, Wooyul Paik, Li Xuan Qin, Crispinita D. Arroyo, Edi Brogi, Monica Morrow, Tari A. King

Open Access Epidemiology

Breast epithelial cell proliferation is markedly increased with short-term high levels of endogenous estrogen secondary to controlled ovarian hyperstimulation

Karine Chung, Linda J. Hovanessian-Larsen, Debra Hawes, DeShawn Taylor, Susan Downey, Darcy V. Spicer, Frank Z. Stanczyk, Sherfaraz Patel, A. Rebecca Anderson, Malcolm C. Pike, Anna H. Wu, Celeste Leigh Pearce

Epidemiology

Serum enterolactone levels and mortality outcome in women with early breast cancer: a retrospective cohort study

Pamela Guglielmini, Alessandra Rubagotti, Francesco Boccardo

Epidemiology

Phenocopy breast cancer rates in Israeli BRCA1 BRCA2 mutation carrier families: is the risk increased in non-carriers?

Shiri Bernholtz, Yael Laitman, Bella Kaufman, Shnai Shimon-Paluch, Eitan Friedman

Open Access Epidemiology

Surgical treatment of early stage breast cancer in elderly: an international comparison

M. Kiderlen, E. Bastiaannet, P. M. Walsh, N. L. Keating, S. Schrodi, J. Engel, W. van de Water, S. M. Ess, L. van Eycken, A. Miranda, L. de Munck, C. J. H. van de Velde, A. J. M. de Craen, G. J. Liefers

Epidemiology

Vitamin D intake, vitamin D receptor polymorphisms, and breast cancer risk among women living in the southwestern U.S.

Dana E. Rollison, Ashley L. Cole, Ko-Hui Tung, Martha L. Slattery, Kathy B. Baumgartner, Tim Byers, Roger K. Wolff, Anna R. Giuliano

Epidemiology

Melatonin pathway genes and breast cancer risk among Chinese women

Sandra L. Deming, Wei Lu, Alicia Beeghly-Fadiel, Ying Zheng, Qiuyin Cai, Jirong Long, Xiao Ou Shu, Yu-Tang Gao, Wei Zheng

Epidemiology

A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population

Aiko Sueta, Hidemi Ito, Takakazu Kawase, Kaoru Hirose, Satoyo Hosono, Yasushi Yatabe, Kazuo Tajima, Hideo Tanaka, Hiroji Iwata, Hirotaka Iwase, Keitaro Matsuo

Epidemiology

Risk of breast cancer in families of multiple affected women and men

Melanie Bevier, Kristina Sundquist, Kari Hemminki

Epidemiology

Pre-diagnosis body mass index and survival after breast cancer in the After Breast Cancer Pooling Project

Marilyn L. Kwan, Wendy Y. Chen, Candyce H. Kroenke, Erin K. Weltzien, Jeannette M. Beasley, Sarah J. Nechuta, Elizabeth M. Poole, Wei Lu, Michelle D. Holmes, Charles P. Quesenberry Jr., John P. Pierce, Xiao Ou Shu, Bette J. Caan

Epidemiology

Genetic variants at chromosome 9p21, 10p15 and 10q22 and breast cancer susceptibility in a Chinese population

Jiaping Chen, Yue Jiang, Xiaoan Liu, Zhenzhen Qin, Juncheng Dai, Guangfu Jin, Hongxia Ma, Shui Wang, Xinru Wang, Zhibin Hu, Hongbing Shen

Brief Report

Optimal outcomes for liver-dominant metastatic breast cancer with transarterial chemoembolization with drug-eluting beads loaded with doxorubicin

Robert C. G. Martin, Ken Robbins, Joan Falcó Fagés, Francisco Diaz Romero, Lisa Rustein, Dana Tomalty, Ricardo Monaco

Brief Report

Melatonin suppresses aromatase expression and activity in breast cancer associated fibroblasts

Kevin C. Knower, Sarah Q. To, Kiyoshi Takagi, Yasuhiro Miki, Hironobu Sasano, Evan R. Simpson, Colin D. Clyne

Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine