Issue 1/2009
Content (52 Articles)
Developments in the clinical understanding of rheumatoid arthritis
Josef S Smolen, Daniel Aletaha
Randomized controlled trial design in rheumatoid arthritis: the past decade
Vibeke Strand, Jeremy Sokolove
Garden of therapeutic delights: new targets in rheumatic diseases
Jean M Waldburger, Gary S Firestein
Transcription profiling of rheumatic diseases
Lisa GM van Baarsen, Carina L Bos, Tineke CTM van der Pouw Kraan, Cornelis L Verweij
Developments in the scientific and clinical understanding of the spondyloarthritides
Joachim Sieper
Gene therapy of the rheumatic diseases: 1998 to 2008
Christopher H Evans, Steven C Ghivizzani, Paul D Robbins
What do biomarkers tell us about the pathogenesis of ankylosing spondylitis?
Walter P Maksymowych
Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis
Barbara Muz, Moddasar N Khan, Serafim Kiriakidis, Ewa M Paleolog
Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair
Christopher L Murphy, Brendan L Thoms, Rasilaben J Vaghjiani, Jérôme E Lafont
Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases
Kathryn M Oliver, Cormac T Taylor, Eoin P Cummins
Cyclophosphamide in systemic sclerosis: still in search of a 'real life' scenario
Irene Miniati, Gabriele Valentini, Marco Matucci Cerinic
Developments in the scientific and clinical understanding of autoinflammatory disorders
Helen J Lachmann, Philip N Hawkins
Interactions among type I and type II interferon, tumor necrosis factor, and β-estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus
Hooi-Ming Lee, Toru Mima, Hidehiko Sugino, Chieko Aoki, Yasuo Adachi, Naoko Yoshio-Hoshino, Kenichi Matsubara, Norihiro Nishimoto
MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage
Yu M Tan, Mikkel Østergaard, Anthony Doyle, Nicola Dalbeth, Maria Lobo, Quentin Reeves, Elizabeth Robinson, William J Taylor, Peter B Jones, Karen Pui, Jamie Lee, Fiona M McQueen
Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysis
Masayoshi Katano, Kazuki Okamoto, Mitsumi Arito, Yuki Kawakami, Manae S Kurokawa, Naoya Suematsu, Sonoko Shimada, Hiroshi Nakamura, Yang Xiang, Kayo Masuko, Kusuki Nishioka, Kazuo Yudoh, Tomohiro Kato
The differential expressions of 78-kDa glucose-regulated protein of infiltrating plasma cells in peripheral joints with the histopathological variants of rheumatoid synovitis
Weijia Dong, Xiaoyan Li, Yuan Feng, Chunmei Fan, Zhinan Chen, Ping Zhu
No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis
Olivier Jaen, Elisabeth Petit-Teixeira, Holger Kirsten, Peter Ahnert, Luca Semerano, Céline Pierlot, Francois Cornelis, Marie-Christophe Boissier, Geraldine Falgarone
Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus
Yi Li, Pui Y Lee, Eric S Sobel, Sonali Narain, Minoru Satoh, Mark S Segal, Westley H Reeves, Hanno B Richards
Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study
Tuulikki Sokka, Sergio Toloza, Maurizio Cutolo, Hannu Kautiainen, Heidi Makinen, Feride Gogus, Vlado Skakic, Humeira Badsha, Tõnu Peets, Asta Baranauskaite, Pál Géher, Ilona Újfalussy, Fotini N Skopouli, Maria Mavrommati, Rieke Alten, Christof Pohl, Jean Sibilia, Andrea Stancati, Fausto Salaffi, Wojciech Romanowski, Danuta Zarowny-Wierzbinska, Dan Henrohn, Barry Bresnihan, Patricia Minnock, Lene Surland Knudsen, Johannes WG Jacobs, Jaime Calvo-Alen, Juris Lazovskis, Geraldo da Rocha Castelar Pinheiro, Dmitry Karateev, Daina Andersone, Sylejman Rexhepi, Yusuf Yazici, Theodore Pincus
Erratum to: What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis – the first 50 years
Dennis McGonagle, Ai Lyn Tan
Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFα-induced MEK/ERK signalling
Jason S Rockel, Suzanne M Bernier, Andrew Leask
The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX-II, is unique compared with other markers of collagen turnover
Anne-Christine Bay-Jensen, Nadine CB Tabassi, Lene V Sondergaard, Thomas L Andersen, Frederik Dagnaes-Hansen, Patrick Garnero, Moustapha Kassem, Jean-Marie Delaissé
Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes
Therese Lindvall, Jenny Karlsson, Rikard Holmdahl, Åsa Andersson
Erratum to: Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies
Michael Mahler, Jennifer T Ngo, Johannes Schulte-Pelkum, Tanja Luettich, Marvin J Fritzler
Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized
David J Hunter, Lou Gerstenfeld, Gavin Bishop, A David Davis, Zach D Mason, Tom A Einhorn, Rose A Maciewicz, Pete Newham, Martyn Foster, Sonya Jackson, Elise F Morgan
Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug
Grant R Zimmermann, William Avery, Alyce L Finelli, Melissa Farwell, Christopher C Fraser, Alexis A Borisy
Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium
Anak ASSK Dharmapatni, Malcolm D Smith, David M Findlay, Christopher A Holding, Andreas Evdokiou, Michael J Ahern, Helen Weedon, Paul Chen, Gavin Screaton, Xiao N Xu, David R Haynes
The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease
Ian D Welch, Matthew F Cowan, Frank Beier, Tully M Underhill
Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration
Kristin Andreas, Thomas Häupl, Carsten Lübke, Jochen Ringe, Lars Morawietz, Anja Wachtel, Michael Sittinger, Christian Kaps
Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent
Noreen Pundt, Marvin A Peters, Christina Wunrau, Simon Strietholt, Carsten Fehrmann, Katja Neugebauer, Christine Seyfert, Frans van Valen, Thomas Pap, Ingmar Meinecke
Distinct synovial immunopathology in Behçet disease and psoriatic arthritis
Juan D Cañete, Raquel Celis, Troy Noordenbos, Conchita Moll, Jose A Gómez-Puerta, Pilar Pizcueta, Antonio Palacin, Paul P Tak, Raimon Sanmartí, Dominique Baeten
Impaired vascular responses to parasympathetic nerve stimulation and muscarinic receptor activation in the submandibular gland in nonobese diabetic mice
Ellen Berggreen, Krister Nyløkken, Nicolas Delaleu, Hamijeta Hajdaragic-Ibricevic, Malin V Jonsson
Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis
Robert D Inman, Basil Chiu
An in vitrostudy investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue
Christine L Le Maitre, Pauline Baird, Anthony J Freemont, Judith A Hoyland
BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance
Balint Farkas, Ferenc Boldizsar, Oktavia Tarjanyi, Anna Laszlo, Simon M Lin, Gabor Hutas, Beata Tryniszewska, Aaron Mangold, Gyorgy Nagyeri, Holly L Rosenzweig, Alison Finnegan, Katalin Mikecz, Tibor T Glant
Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients
Katharina Hanke, Claudia S Brückner, Cornelia Dähnrich, Dörte Huscher, Lars Komorowski, Wolfgang Meyer, Anthonia Janssen, Marina Backhaus, Mike Becker, Angela Kill, Karl Egerer, Gerd R Burmester, Falk Hiepe, Wolfgang Schlumberger, Gabriela Riemekasten
Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise?
Johannes WG Jacobs, Johannes WJ Bijlsma
The proliferative human monocyte subpopulation contains osteoclast precursors
Roya Lari, Peter D Kitchener, John A Hamilton
Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice
Margaret K Gatumu, Kathrine Skarstein, Adrian Papandile, Jeffrey L Browning, Roy A Fava, Anne Isine Bolstad
In vitromodel for the analysis of synovial fibroblast-mediated degradation of intact cartilage
David Pretzel, Dirk Pohlers, Sönke Weinert, Raimund W Kinne
Recent developments in anti-rheumatic drugs in pediatrics: treatment of juvenile idiopathic arthritis
Kristen Hayward, Carol A Wallace
Medication persistence over 2 years of follow-up in a cohort of early rheumatoid arthritis patients: associated factors and relationship with disease activity and with disability
Virginia Pascual-Ramos, Irazú Contreras-Yáñez, Antonio R Villa, Javier Cabiedes, Marina Rull-Gabayet
Reduced IgG anti-small nuclear ribonucleoprotein autoantibody production in systemic lupus erythematosus patients with positive IgM anti-cytomegalovirus antibodies
Claudia Azucena Palafox Sánchez, Minoru Satoh, Edward KL Chan, Wendy C Carcamo, José Francisco Muñoz Valle, Gerardo Orozco Barocio, Edith Oregon Romero, Rosa Elena Navarro Hernández, Mario Salazar Páramo, Antonio Cabral Castañeda, Mónica Vázquez del Mercado
Diagnostic value of anti-topoisomerase I antibodies in a large monocentric cohort
Katharina Hanke, Cornelia Dähnrich, Claudia S Brückner, Dörte Huscher, Mike Becker, Anthonina Jansen, Wolfgang Meyer, Karl Egerer, Falk Hiepe, Gerd R Burmester, Wolfgang Schlumberger, Gabriela Riemekasten
In memoriam: Professor Brian Maurice John Foxwell, 1956 to 2008
Fionula Brennan, Marc Feldmann
Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study
Vaidehi R Chowdhary, Cynthia S Crowson, Kimberly P Liang, Clement J Michet Jr, Dylan V Miller, Kenneth J Warrington, Eric L Matteson