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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2022

Open Access 01-12-2022 | Splenectomy | Case report

Giant splenic cyst complicated by infection due to Salmonella enterica serovar Livingstone in a previously healthy adolescent male: a case report

Authors: Junyan Qu, Zhiyong Zong

Published in: BMC Infectious Diseases | Issue 1/2022

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Abstract

Background

Splenic cyst complicated by non-typhoid Salmonella infection is rare in healthy individuals in the era of antibiotics. Salmonella enterica subsp. enterica serovar Livingstone causing infection of giant splenic cyst has not been previously reported.

Case presentation

We report a case of giant splenic cyst (maximum diameter, 21 cm) complicated with Salmonella Livingstone infection, which resulted in splenic abscess, in a 16-year-old previously healthy adolescent male. The splenic abscess was successfully treated with ultrasonography-guided percutaneous drainage and antimicrobial therapy.

Conclusion

Infection of splenic cyst may be caused by S. Livingstone in immunocompetent individuals. This case may help clinicians to raise awareness towards splenic abscess and highlights the importance of drainage and antimicrobial agents to avoid splenectomy.
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Literature
1.
Bresadola V, Pravisani R, Terrosu G, Risaliti A. Laparoscopic splenectomy as the definitive investigation for differential diagnosis of elevated serum CA 19-9 levels associated with a splenic cyst: case report and review of the literature. J Surg. 2013;1(1):6.
2.
Morgenstern L. Nonparasitic splenic cysts: pathogenesis, classification, and treatment. J Am Coll Surg. 2002;194(3):306–14.CrossRef
3.
Garg M, Kataria SP, Sethi D, Mathur SK. Epidermoid cyst of spleen mimicking splenic lymphangioma. Adv Biomed Res. 2013;2:49.CrossRef
4.
Ingle SB, Hinge Ingle CR, Patrike S. Epithelial cysts of the spleen: a minireview. World J Gastroenterol. 2014;20(38):13899–903.CrossRef
5.
Ooi LL, Leong SS. Splenic abscesses from 1987 to 1995. Am J Surg. 1997;174(1):87–93.CrossRef
6.
Liu YH, Liu CP, Lee CM. Splenic abscesses at a tertiary medical center in northern Taiwan. J Microbiol Immunol Infect. 2014;47(2):104–8.CrossRef
7.
Manzar N, Almuqamam M, Kaushik K, Dahabra L, Falcone M, Rimareva N, et al. Primary non-typhoidal Salmonella infection presenting as a splenic abscess in a healthy adolescent male. Infez Med. 2019;27(1):77–81.PubMed
8.
Karia N, Lakhoo K. Complicated congenital splenic cyst: saved by a splenunculus. Afr J Paediatr Surg. 2011;8(1):98–100.CrossRef
9.
Koh CC, Wang NL, Lee HC, Duh YC. Infected congenital splenic cyst associated with duodenal duplication cyst and malrotation—a case report. J Pediatr Surg. 2007;42(12):e21–2.CrossRef
10.
Guillén S, Marcén M, Álvarez I, Mañas P, Cebrián G. Stress resistance of emerging poultry-associated Salmonella serovars. Int J Food Microbiol. 2020;335: 108884.CrossRef
11.
Guerin PJ, De Jong B, Heir E, Hasseltvedt V, Kapperud G, et al. Outbreak of Salmonella Livingstone infection in Norway and Sweden due to contaminated processed fish products. Epidemiol Infect. 2004;132(5):889–95.CrossRef
12.
Bouallègue-Godet O, Ben Salem Y, Fabre L, Demartin M, Grimont PA, Mzoughi R, et al. Nosocomial outbreak caused by Salmonella enterica serotype Livingstone producing CTX-M-27 extended-spectrum beta-lactamase in a neonatal unit in Sousse, Tunisia. J Clin Microbiol. 2005;43(3):1037–44.CrossRef
13.
Zhang H, Ye Y, Yang B, Gu Q, Zhu Y, Que F, et al. Characterization of an unusual foodborne illness including an outbreak and sporadic illness caused by three bacterial pathogens via a takeaway service. Foodborne Pathog Dis. 2019;16(9):616–21.CrossRef
14.
Guedda I, Taminiau B, Ferjani A, Boukadida J, Bertrand S, Daube G. Antimicrobial and molecular analysis of Salmonella serovar Livingstone strains isolated from humans in Tunisia and Belgium. J Infect Dev Ctries. 2014;8(8):973–80.CrossRef
15.
Liang JT, Lee PH, Wang SM, Chang KJ. Splenic abscess: a diagnostic pitfall in the ED. Am J Emerg Med. 1995;13(3):337–43.CrossRef
16.
Reilly WJ, Forbes GI, Sharp JC, Oboegbulem SI, Collier PW, Paterson GM. Poultry-borne salmonellosis in Scotland. Epidemiol Infect. 1988;101(1):115–22.CrossRef
17.
Feasey NA, Dougan G, Kingsley RA, Heyderman RS, Gordon MA. Invasive non-typhoidal Salmonella disease: an emerging and neglected tropical disease in Africa. Lancet. 2012;379(9835):2489–99.CrossRef
18.
Graham SM, Walsh AL, Molyneux EM, Phiri AJ, Molyneux ME. Clinical presentation of non-typhoidal Salmonella bacteraemia in Malawian children. Trans R Soc Trop Med Hyg. 2000;94(3):310–4.CrossRef
19.
Bronzan RN, Taylor TE, Mwenechanya J, Tembo M, Kayira K, Bwanaisa L, et al. Bacteremia in Malawian children with severe malaria: prevalence, etiology, HIV coinfection, and outcome. J Infect Dis. 2007;195(6):895–904.CrossRef
20.
Gilchrist JJ, MacLennan CA, Hill AV. Genetic susceptibility to invasive Salmonella disease. Nat Rev Immunol. 2015;15(7):452–63.CrossRef
21.
de Beaucoudrey L, Samarina A, Bustamante J, Cobat A, Boisson-Dupuis S, Feinberg J, et al. Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries. Medicine. 2010;89(6):381–402.CrossRef
22.
Raffatellu M, Santos RL, Verhoeven DE, George MD, Wilson RP, Winter SE, et al. Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med. 2008;14(4):421–8.CrossRef
23.
Cunnington AJ, de Souza JB, Walther M, Riley EM. Malaria impairs resistance to Salmonella through heme- and heme oxygenase-dependent dysfunctional granulocyte mobilization. Nat Med. 2011;18(1):120–7.CrossRef
24.
Smyrniotis V, Kehagias D, Voros D, Fotopoulos A, Lambrou A, Kostopanagiotou G, et al. Splenic abscess. An old disease with new interest. Dig Surg. 2000;17(4):354–7.CrossRef
25.
Alvi AR, Kulsoom S, Shamsi G. Splenic abscess: outcome and prognostic factors. J Coll Physicians Surg Pak. 2008;18(12):740–3.PubMed
26.
Divyashree S, Gupta N. Splenic abscess in immunocompetent patients managed primarily without splenectomy: a series of 7 cases. Perm J. 2017;21:16–139.PubMedPubMedCentral
27.
Sammon J, Twomey M, Crush L, Maher MM, O’Connor OJ. Image-guided percutaneous splenic biopsy and drainage. Semin Intervent Radiol. 2012;29(4):301–10.CrossRef
28.
Lee HW, Han SB. Large splenic abscess caused by non-typhoidal Salmonella in a healthy child treated with percutaneous drainage. Children. 2020;7(8):88.CrossRef
29.
Comarmond C, Jauréguiberry S, Vaillant JC, Lecso M, Bricaire F, Caumes E. Giant splenic abscess due to Salmonella enteritidis in a returning traveler. J Travel Med. 2010;17(4):271–3.CrossRef
30.
Zerem E, Bergsland J. Ultrasound guided percutaneous treatment for splenic abscesses: the significance in treatment of critically ill patients. World J Gastroenterol. 2006;12(45):7341–5.CrossRef
31.
Termos S, Othman F, Aljewaied A, Alkhalil AM, Alhunaidi M, Parayil SM, et al. Symptomatic giant primary nonparasitic splenic cyst treated with laparoscopic decapsulation: a case report and literature review. Am J Case Rep. 2020;21: e927893.CrossRef
Metadata
Title
Giant splenic cyst complicated by infection due to Salmonella enterica serovar Livingstone in a previously healthy adolescent male: a case report
Authors
Junyan Qu
Zhiyong Zong
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2022
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-022-07529-6

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