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01-06-2020 | Smelling Disorder | Case Report

A special symptom of olfactory dysfunction in coronavirus disease 2019: report of three cases

Authors: Chen Chen, Moxian Chen, Cong Cheng, Yun Chi, Zhiliang Hu, Yuan Liu, Shan Huang, Yanling Lv, Chongfeng Liang, Damin Jiao, Yongxiang Yi, Xia Zhang, Wenkui Sun, Hongxia Wei

Published in: Journal of NeuroVirology | Issue 3/2020

Abstract

Three patients of coronavirus disease (COVID-19) showed the symptoms of olfactory dysfunction. Clinical characteristics and treatment were retrospective analyzed. Olfactory disorders are uncommon symptoms of COVID-19 in China. Early diagnosis and intervention are keys to the recovery of olfactory disorders. Particular attention should be devoted to olfactory dysfunction.

Gralinski LE, Menachery VD (2020) Return of the coronavirus: 2019-nCoV. Viruses 12:E135CrossRefPubMed

Harless L, Liang J (2016) Pharmacologic treatment for postviral olfactory dysfunction: a systematic review. Int Forum Allergy Rhinol 6:760–767CrossRefPubMed

Hwang CS (2006) Olfactory neuropathy in severe acute respiratory syndrome: report of a case. Acta Neurol Taiwanica 15:26–28

Lechien JR, Chiesa-Estomba CM, De Siati DR, Horoi M, Le Bon SD, Rodriguez A, Dequanter D, Blecic S, El Afia F, Distinguin L, Chekkoury-Idrissi Y, Hans S, Delgado IL, Calvo-Henriquez C, Lavigne P, Falanga C, Barillari MR, Cammaroto G, Khalife M, Leich P, Souchay C, Rossi C, Journe F, Hsieh J, Edjlali M, Carlier R, Ris L, Lovato A, De Filippis C, Coppee F, Fakhry N, Ayad T, Saussez S (2020). Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study. Eur Arch Otorhinolaryngol. 2020. doi: https://doi.org/10.1007/s00405-020-05965-1. Online ahead of print

Schriever VA, Merkonidis C, Gupta N, Hummel C, Hummel T (2012) Treatment of smell loss with systemic methylprednisolone. Rhinology 50:284–289CrossRefPubMed

Tsai LK, Hsieh ST, Chao CC, Chen YC, Lin YH, Chang SC, Chang YC (2005) Neuromuscular Disorders in Severe Acute Respiratory Syndrome. 61:1669

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z (2020) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 323:1061. https://doi.org/10.1001/jama.2020.1585 CrossRefPubMedPubMedCentral

Xu H, Zhong L, Deng J, Peng J, Dan H, Zeng X, Li T, Chen Q (2020) High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int J Oral Sci 12:8CrossRefPubMedPubMedCentral

Zou X, Chen K, Zou J, Han P, Hao J, Han Z (2020). Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. Front Med

Title: A special symptom of olfactory dysfunction in coronavirus disease 2019: report of three cases
Authors: Chen Chen
Moxian Chen
Cong Cheng
Yun Chi
Zhiliang Hu
Yuan Liu
Shan Huang
Yanling Lv
Chongfeng Liang
Damin Jiao
Yongxiang Yi
Xia Zhang
Wenkui Sun
Hongxia Wei
Publication date: 01-06-2020
Publisher: Springer International Publishing
Keywords: Smelling Disorder
Coronavirus
Cough
SARS-CoV-2
Cough
Smelling Disorder
Cough
COVID-19
Taste Disorder
Published in: Journal of NeuroVirology / Issue 3/2020
Print ISSN: 1355-0284
Electronic ISSN: 1538-2443
DOI: https://doi.org/10.1007/s13365-020-00849-w

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A special symptom of olfactory dysfunction in coronavirus disease 2019: report of three cases

Abstract

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Abstract

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