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Published in: International Journal of Clinical Pharmacy 1/2018

01-02-2018 | Research Article

Sildenafil citrate use in Addis Ababa: characteristics of users and pharmacists’ dispensing practices

Authors: Dawit Teshome Gebregeorgise, Yajeb Melesse Belay, Sofia Kälvemark Sporrong

Published in: International Journal of Clinical Pharmacy | Issue 1/2018

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Abstract

Background Studies have reported misuse of sildenafil citrate for recreational purpose, not least by healthy young men. This is becoming a major concern, for medical and other reasons. Objective The aim of this study was to document the characteristics of sildenafil citrate users and to explore the dispensing practices of the medicine in selected community pharmacies in Addis Ababa, Ethiopia. Setting Data was collected in community pharmacies in Addis Ababa, Ethiopia. Method A survey, using a self-administrated questionnaire, was conducted among customers who purchased sildenafil citrate from community pharmacies. Simple descriptive statistics were used to analyse data. Also, semi-structured interviews were conducted with community pharmacists. These were analysed thematically. Main outcome measures Socio-demographic characteristics (survey), themes (interviews). Results All survey respondents (n = 197) were men, 57.9% were below 40 years old, 53.8% had never been married and 58.4% had used sildenafil citrate before. A minority (16.2%) were diagnosed with erectile dysfunction. The main reason for buying sildenafil citrate was experimentation (45.7%). Pharmacists reported that sildenafil citrate was often dispensed without a prescription. The reason for this was, according to the interviewees, competition in the market. Also, the medicine was often dispensed without adequate information or counselling. Conclusions Selling and buying sildenafil citrate without a prescription seems to be common practice in pharmacies in Addis Ababa. It is crucial to strengthen the regulatory activity to protect customers from health risks. In addition pharmacy professionals should be supported to work in accordance with professional and legal standards.
Literature
1.
go back to reference Anonymous 1993. NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA. 1993;270:83–90. Anonymous 1993. NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA. 1993;270:83–90.
3.
go back to reference Stranne J, Malmsten UG, Areskoug B, Milsom I, Molander U, Peeker R. Influence of age and changes over time on erectile dysfunction: results from two large cross-sectional surveys 11 years apart. Scand J Urol. 2013;47:198–205.CrossRefPubMed Stranne J, Malmsten UG, Areskoug B, Milsom I, Molander U, Peeker R. Influence of age and changes over time on erectile dysfunction: results from two large cross-sectional surveys 11 years apart. Scand J Urol. 2013;47:198–205.CrossRefPubMed
4.
go back to reference Oladiji F, Kayode OO, Parakoyi DB. Influence of socio-demographic characteristics on prevalence of erectile dysfunction in Nigeria. Int J Impot Res. 2013;25:18–23.CrossRefPubMed Oladiji F, Kayode OO, Parakoyi DB. Influence of socio-demographic characteristics on prevalence of erectile dysfunction in Nigeria. Int J Impot Res. 2013;25:18–23.CrossRefPubMed
6.
go back to reference Al-Hunayan A, Al-Mutar M, Kehinde EO, Thalib L, Al-Ghorory M. The prevalence and predictors of erectile dysfunction in men with newly diagnosed with type 2 diabetes mellitus. BJU Int. 2007;99:130–4.CrossRefPubMed Al-Hunayan A, Al-Mutar M, Kehinde EO, Thalib L, Al-Ghorory M. The prevalence and predictors of erectile dysfunction in men with newly diagnosed with type 2 diabetes mellitus. BJU Int. 2007;99:130–4.CrossRefPubMed
7.
go back to reference Njuguna J, Olieva S, Muruka C, Owek C. Khat consumption in Masalani town, Northeastern Kenya. J Psychoact Drugs. 2013;45:355–9.CrossRef Njuguna J, Olieva S, Muruka C, Owek C. Khat consumption in Masalani town, Northeastern Kenya. J Psychoact Drugs. 2013;45:355–9.CrossRef
8.
go back to reference Freitas D, Athanazio R, Almeida D, Dantas N, Reis F. Sildenafil improves quality of life in men with heart failure and erectile dysfunction. Int J Impot Res. 2006;18:210–2.CrossRefPubMed Freitas D, Athanazio R, Almeida D, Dantas N, Reis F. Sildenafil improves quality of life in men with heart failure and erectile dysfunction. Int J Impot Res. 2006;18:210–2.CrossRefPubMed
9.
go back to reference Hackett G, Kell P, Ralph D, Dean J, Price D, Speakman M, Wylie K. British Society for sexual medicine guidelines on the management of erectile dysfunction. J Sex Med. 2008;5:1841–65.CrossRefPubMed Hackett G, Kell P, Ralph D, Dean J, Price D, Speakman M, Wylie K. British Society for sexual medicine guidelines on the management of erectile dysfunction. J Sex Med. 2008;5:1841–65.CrossRefPubMed
10.
go back to reference Mulhall JP, Montorsi F. Evaluating preference trials of oral phosphodiesterase 5 inhibitors for erectile dysfunction. Eur Urol. 2006;49:30–7.CrossRefPubMed Mulhall JP, Montorsi F. Evaluating preference trials of oral phosphodiesterase 5 inhibitors for erectile dysfunction. Eur Urol. 2006;49:30–7.CrossRefPubMed
11.
go back to reference Vickers MA, Satyanarayana R. Phosphodiesterase type 5 inhibitors for the treatment of erectile dysfunction in patients with diabetes mellitus. Int J Impot Res. 2002;14:466–71.CrossRefPubMed Vickers MA, Satyanarayana R. Phosphodiesterase type 5 inhibitors for the treatment of erectile dysfunction in patients with diabetes mellitus. Int J Impot Res. 2002;14:466–71.CrossRefPubMed
12.
go back to reference Ghofrani HA, Osterloh IH, Grimminger F. Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond. Nat Rev Drug Discov. 2006;5:689–702.CrossRefPubMed Ghofrani HA, Osterloh IH, Grimminger F. Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond. Nat Rev Drug Discov. 2006;5:689–702.CrossRefPubMed
13.
go back to reference Harte CB, Meston CM. Recreational use of erectile dysfunction medications in undergraduate men in the United States: characteristics and associated risk factors. Arch Sex Behav. 2011;40:597–606.CrossRefPubMed Harte CB, Meston CM. Recreational use of erectile dysfunction medications in undergraduate men in the United States: characteristics and associated risk factors. Arch Sex Behav. 2011;40:597–606.CrossRefPubMed
14.
go back to reference Bechara A, Casabe A, De Bonis W, Helien A, Bertolino MV. Recreational use of phosphodiesterase type 5 inhibitors by healthy young men. J Sex Med. 2010;7:3736–42.CrossRefPubMed Bechara A, Casabe A, De Bonis W, Helien A, Bertolino MV. Recreational use of phosphodiesterase type 5 inhibitors by healthy young men. J Sex Med. 2010;7:3736–42.CrossRefPubMed
15.
go back to reference Mitchell KR, Prah P, Mercer CH, Datta J, Tanton C, Macdowall W, Copas AJ, Clifton S, Sonnenberg P, Field N, Johnson AM, Wellings K. Medicated sex in Britain: evidence from the third National Survey of Sexual Attitudes and Lifestyles. Sex Transm Infect. 2016;92:32–8.CrossRefPubMed Mitchell KR, Prah P, Mercer CH, Datta J, Tanton C, Macdowall W, Copas AJ, Clifton S, Sonnenberg P, Field N, Johnson AM, Wellings K. Medicated sex in Britain: evidence from the third National Survey of Sexual Attitudes and Lifestyles. Sex Transm Infect. 2016;92:32–8.CrossRefPubMed
16.
go back to reference Korkes F, Costa-Matos A, Gasperini R, Reginato PV, Perez MDC. Recreational use of PDE5 inhibitors by young healthy men: recognizing this issue among medical students. J Sex Med. 2008;5:2414–8.CrossRefPubMed Korkes F, Costa-Matos A, Gasperini R, Reginato PV, Perez MDC. Recreational use of PDE5 inhibitors by young healthy men: recognizing this issue among medical students. J Sex Med. 2008;5:2414–8.CrossRefPubMed
17.
go back to reference Tsai WK, Jiann BP. Data on the utilization of treatment modalities for ED in Taiwan in the era of PDE5 inhibitors. Int J Impot Res. 2014;26:141–5.CrossRefPubMed Tsai WK, Jiann BP. Data on the utilization of treatment modalities for ED in Taiwan in the era of PDE5 inhibitors. Int J Impot Res. 2014;26:141–5.CrossRefPubMed
21.
go back to reference Tesso DW, Fantahun MA, Enquselassie F. Parent-young people communication about sexual and reproductive health in E/Wollega zone, West Ethiopia: implications for interventions. Reprod Health. 2012;9:13.CrossRefPubMedPubMedCentral Tesso DW, Fantahun MA, Enquselassie F. Parent-young people communication about sexual and reproductive health in E/Wollega zone, West Ethiopia: implications for interventions. Reprod Health. 2012;9:13.CrossRefPubMedPubMedCentral
24.
go back to reference Alahdal A, Noor A, Bagalagel A. Use pattern of oral PDE-5 inhibitors in Jeddah, Saudi Arabia. JKAU Med Sci. 2008;15:27–38.CrossRef Alahdal A, Noor A, Bagalagel A. Use pattern of oral PDE-5 inhibitors in Jeddah, Saudi Arabia. JKAU Med Sci. 2008;15:27–38.CrossRef
25.
go back to reference Hsieh H-F, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15:1277–88.CrossRefPubMed Hsieh H-F, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15:1277–88.CrossRefPubMed
26.
go back to reference Kimura M, Shimura S, Kobayashi H, Tai T, Chikano Y, Baba S, Kano M, Nagao K. Profiling characteristics of men who use phosphodiesterase type 5 inhibitors based on obtaining patterns: data from the nationwide Japanese population. J Sex Med. 2012;9:1649–58.CrossRefPubMed Kimura M, Shimura S, Kobayashi H, Tai T, Chikano Y, Baba S, Kano M, Nagao K. Profiling characteristics of men who use phosphodiesterase type 5 inhibitors based on obtaining patterns: data from the nationwide Japanese population. J Sex Med. 2012;9:1649–58.CrossRefPubMed
27.
go back to reference Simopoulos EF, Trinidad AC. Male erectile dysfunction: integrating psychopharmacology and psychotherapy. Gen Hosp Psychiatry. 2013;35:33–8.CrossRefPubMed Simopoulos EF, Trinidad AC. Male erectile dysfunction: integrating psychopharmacology and psychotherapy. Gen Hosp Psychiatry. 2013;35:33–8.CrossRefPubMed
28.
go back to reference Gareri P, Castagna A, Francomano D, Cerminara G, De Fazio P. Erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives. Int J Endocrinol. 2014;2014:878670.CrossRefPubMedPubMedCentral Gareri P, Castagna A, Francomano D, Cerminara G, De Fazio P. Erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives. Int J Endocrinol. 2014;2014:878670.CrossRefPubMedPubMedCentral
29.
go back to reference Mondaini N, Ponchietti R, Muir GH, Montorsi F, Di Loro F, Lombardi G, Rizzo M. Sildenafil does not improve sexual function in men without erectile dysfunction but does reduce the postorgasmic refractory time. Int J Impot Res. 2003;15:225–8.CrossRefPubMed Mondaini N, Ponchietti R, Muir GH, Montorsi F, Di Loro F, Lombardi G, Rizzo M. Sildenafil does not improve sexual function in men without erectile dysfunction but does reduce the postorgasmic refractory time. Int J Impot Res. 2003;15:225–8.CrossRefPubMed
30.
go back to reference Santtila P, Sandnabba NK, Jern P, Varjonen M, Witting K, von der Pahlen B. Recreational use of erectile dysfunction medication may decrease confidence in ability to gain and hold erections in young males. Int J Impot Res. 2007;19:591–6.CrossRefPubMed Santtila P, Sandnabba NK, Jern P, Varjonen M, Witting K, von der Pahlen B. Recreational use of erectile dysfunction medication may decrease confidence in ability to gain and hold erections in young males. Int J Impot Res. 2007;19:591–6.CrossRefPubMed
34.
go back to reference Wu C, Zhanag H, Gao Y, Tan A, Yang X, Lu Z, Zhang Y, Liao M, Wang M, Mo Z. The association of smoking and erectile dysfunction: results from the Fangchenggang Area Male Health and Examination Survey (FAMHES). J Androl. 2012;33:59–65.CrossRefPubMed Wu C, Zhanag H, Gao Y, Tan A, Yang X, Lu Z, Zhang Y, Liao M, Wang M, Mo Z. The association of smoking and erectile dysfunction: results from the Fangchenggang Area Male Health and Examination Survey (FAMHES). J Androl. 2012;33:59–65.CrossRefPubMed
35.
go back to reference Teshome D, Gedif T. Determinants of alcohol drinking and its association with sexual practices among high school students in Addis Ababa, Ethiopia: cross sectional study. Open J Prev Med. 2013;3:420–7.CrossRef Teshome D, Gedif T. Determinants of alcohol drinking and its association with sexual practices among high school students in Addis Ababa, Ethiopia: cross sectional study. Open J Prev Med. 2013;3:420–7.CrossRef
37.
go back to reference Astatkie A, Demissie M, Berhane Y, Worku A. Prevalence of and factors associated with regular khat chewing among university students in Ethiopia. Subst Abuse Rehabil. 2015;6:41–50.CrossRefPubMedPubMedCentral Astatkie A, Demissie M, Berhane Y, Worku A. Prevalence of and factors associated with regular khat chewing among university students in Ethiopia. Subst Abuse Rehabil. 2015;6:41–50.CrossRefPubMedPubMedCentral
38.
go back to reference Mohammed A, Engidawork E. Reproductive parameters are differentially altered following subchronic administration of Catha edulis F. (Khat) extract and cathinone in male rats. J Ethnopharmacol. 2011;134:977–83.CrossRefPubMed Mohammed A, Engidawork E. Reproductive parameters are differentially altered following subchronic administration of Catha edulis F. (Khat) extract and cathinone in male rats. J Ethnopharmacol. 2011;134:977–83.CrossRefPubMed
39.
go back to reference Deressa W, Azazh A. Substance use and its predictors among undergraduate medical students of Addis Ababa University in Ethiopia. BMC Public Health. 2011;11:660.CrossRefPubMedPubMedCentral Deressa W, Azazh A. Substance use and its predictors among undergraduate medical students of Addis Ababa University in Ethiopia. BMC Public Health. 2011;11:660.CrossRefPubMedPubMedCentral
40.
go back to reference Elmerstig E, Wijma B, Sandell K, Berterö C. Sexual interaction or a solitary action: young Swedish men’s ideal images of sexual situations in relationships and in one-night stands. Sex Reprod Healthc. 2014;5:149–55.CrossRefPubMed Elmerstig E, Wijma B, Sandell K, Berterö C. Sexual interaction or a solitary action: young Swedish men’s ideal images of sexual situations in relationships and in one-night stands. Sex Reprod Healthc. 2014;5:149–55.CrossRefPubMed
41.
go back to reference Both R. A matter of sexual confidence. Young men’s non-prescription use of Viagra in Addis Ababa, Ethiopia. Cult Health Sex. 2016;18:495–508.CrossRefPubMed Both R. A matter of sexual confidence. Young men’s non-prescription use of Viagra in Addis Ababa, Ethiopia. Cult Health Sex. 2016;18:495–508.CrossRefPubMed
Metadata
Title
Sildenafil citrate use in Addis Ababa: characteristics of users and pharmacists’ dispensing practices
Authors
Dawit Teshome Gebregeorgise
Yajeb Melesse Belay
Sofia Kälvemark Sporrong
Publication date
01-02-2018
Publisher
Springer International Publishing
Published in
International Journal of Clinical Pharmacy / Issue 1/2018
Print ISSN: 2210-7703
Electronic ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-017-0558-8

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