Top

Published in:

01-06-2019 | Sexually Transmitted Infection | Commentary

Pre-exposure Prophylaxis for HIV Infection: Preventing Disease or Promoting Sexual Health?

Authors: Ronald O. Valdiserri, David R. Holtgrave

Published in: Journal of Community Health | Issue 3/2019

Excerpt

Practitioners of public health recognize that disease prevention and health promotion occupy the same continuum of activities that are aimed at improving individual and population health. Closely related as they are, however, these two domains are not identical—either in concept or in practice. Their differences owe to the widely-accepted definition of health as a state of “complete physical, mental and social well-being and not merely the absence of disease or infirmity” [1]. Namely, while the absence of disease brought about by prevention activities is a laudable goal and an important component of health, it may not be the only condition necessary to achieve and sustain overall health. …

World Health Organization. (1946). Constitution of the World Health Organization. Retrieved Oct 25, 2018, from https://www.who.int/about/mission/en/.

Edwards, W. M., & Coleman, E. (2004). Defining sexual health: A descriptive overview. Archives of Sexual Behavior, 33(3), 189–195.CrossRefPubMed

World Health Organization. (2010). Developing sexual health programs: A framework for action. Retrieved Oct 29, 2018, from https://www.who.int/reproductivehealth/publications/sexual_health/rhr_hrp_10...en/.

Ford, J. V., Ivankovich, M. B., Douglas, J. M., et al. (2017). The Need to promote sexual health in America: A new vision for public health action. Sexually Transmitted Diseases, 44(10), 579–585.CrossRefPubMed

Grant, R. M., Lama, J. R., Anderson, P. L., et al. (2010). Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. New England Journal of Medicine, 363(27), 2587–2599.CrossRefPubMed

Smith, D. K., Grant, R. M., Weidle, P. J., Lansky, A., Mermin, J., & Fenton, K. A. (2011). Interim guidance: Preexposure prophylaxis for the prevention of HIV infection in men who have sex with men. Morbidity and Mortality Weekly Report, 60(3), 65–68.

Smith, D. K., Thigpen, M. C., Nesheim, S. R., et al. (2012). Interim guidance for clinicians considering the use of preexposure prophylaxis for the prevention of HIV infection in heterosexually active adults. Morbidity and Mortality Weekly Report, 61(31), 586–589.

Smith, D. K., Martin, M., Lansky, A., Mermin, J., & Choopanya, K. (2013). Update to interim guidance for preexposure prophylaxis (PrEP) for the prevention of HIV infection: PrEP for injecting drug users. Morbidity and Mortality Weekly Report, 62(23), 463–465.PubMedCentral

Food and Drug Administration. (2012). FDA approves first drug for reducing the risk of sexually acquired HIV infection. Retrieved Oct 31, 2018, from https://aidsinfo.nih.gov/news/1254/fda-approves-first-drug-for-reducing-the-risk-of-sexually-acquired-hiv-infection.

10.

Centers for Disease Control and Prevention: US Public Health Service. (2014). Preexposure Prophylaxis for the Prevention of HIV Infection in the United States: A Clinical Practice Guideline. Published May 14, 2014. Note: 2014 PrEP Guidelines are no longer maintained by CDC.

11.

Ryan, B. (2018). FDA Approves Truvada as PrEP for Adolescents at Risk for HIV. POZ. Retrieved Nov 1, 2018, from https://www.poz.com/articel/fda-approves-truvada-prep-adolescents-risk-hiv.

12.

Office of National AIDS Policy. (2015). National HIV/AIDS Strategy for the United States: Updated to 2020. Retrieved Nov 3, 2018, from https://obamawhitehouse.archives.gov/sites/default/files/docs/national_hiv_aids_strategy_update_2020.pdf.

13.

Jenness, S. M., Goodreau, S. M., Rosenberg, E., Beylerian, E. N., Hoover, K. W., Smith, D. K., & Sullivan, P. (2016). Impact of the Centers for Disease Control’s HIV preexposure prophylaxis guidelines for men who have sex with men in the United States. Journal of Infectious Diseases, 214(12), 1800–1807.CrossRefPubMed

14.

Sullivan, P. S., Giler, R. M., Mouhanna, F., et al. (2018). Trends in the use of oral emtricitabine/tenofovir disoproxil fumarate for pre-exposure prophylaxis against HIV infection, United States, 2012–2017. Annals of Epidemiology, 12(12), 833-840.

15.

Huang, Y. A., Zhu, W., Smith, D. K., Harris, N., & Hoover, K. W. (2018). HIV preexposure prophylaxis, by race and ethnicity—United States, 2014–2016. Morbidity and Mortality Weekly Report, 67(41), 1147–1150.CrossRefPubMedPubMedCentral

16.

Harawa, N., McBride, S., Leibowitz, A., Pulsipher, C., & Holloway, I. (2018). Examining PrEP Uptake among Medi-Cal Beneficiaries in California: Differences by Age, Gender, Race/Ethnicity and Geographic Region. California HIV/AIDS Policy Research Centers. Retrieved Nov 5, 2018, from http://www.chprc.org/examining-prep-uptake-among-medi-cal-beneficiaries-in-california/.

17.

Green, L. W., Ottoson, J. M., Garcia, C., & Hiatt, R. A. (2009). Diffusion theory and knowledge dissemination, utilization and integration in public health. Annual Review of Public Health, 30, 151–174.CrossRefPubMed

18.

Smith, D. K., Mendoza, M. C., Stryker, J. E., & Rose, C. E. (2016). PrEP awareness and attitudes in a national survey of primary care clinicians in the United States, 2009–2015. PLoS ONE, 11 (6), e0156592.CrossRefPubMedPubMedCentral

19.

Misra, K., & Udeaugu, C. C. (2017). Disparities in awareness of HIV postexposure and preexposure prophylaxis among notified partners of HIV-positive individuals, New York City 2015–2017. Journal of Acquired Immune Deficiency Syndromes, 76(2), 132–140.CrossRefPubMed

20.

Eaton, L. A., Kalichman, S. C., Price, D., Finneran, S., Allen, A., & Maksut, J. (2017). Stigma and conspiracy beliefs related to pre-exposure prophylaxis (PrEP) and interest in using PrEP among black and white men and transgender women who have sex with men. AIDS and Behavior, 21(5), 1236–1246.CrossRefPubMedPubMedCentral

21.

Calabrese, S. K., Dovidio, J. F., Tekeste, M., et al. (2018). HIV pre-exposure prophylaxis stigma as a multidimensional barrier to uptake among women who attend planned parenthood. Journal of Acquired Immune Deficiency Syndromes, 79(1), 46–53.CrossRefPubMed

22.

Eaton, L. A., Driffin, D. D., Smith, H., Conway-Washington, C., White, D., & Cherry, C. (2014). Psycho-social factors related to willingness to use pre-exposure prophylaxis for HIV prevention among black men who have sex with men attending a community event. Sexual Health, 11(3), 244–251.CrossRefPubMedPubMedCentral

23.

Lelutiu-Weinberger, C., & Golub, S. A. (2016). Enhancing PrEP access for black and latino men who have sex with men. Journal of Acquired Immune Deficiency Syndromes, 73(5), 547–555.CrossRefPubMed

24.

Cahill, S., Taylor, S. W., Elesser, S. A., Mena, L., Hickson, D., & Mayer, K. H. (2017). Stigma, medical mistrust, and perceived racism may affect PrEP awareness and uptake in black compared to white gay and bisexual men in Jackson, Mississippi and Boston, Massachusetts. AIDS Care, 29(11), 1351–1358.CrossRefPubMedPubMedCentral

25.

Smith, D. K., Van Handel, M., & Grey, J. (2018). Estimates of adults with indications for HIV pre-exposure prophylaxis by jurisdiction, transmission risk group, and race/ethnicity, United States, 2015. Annals of Epidemiology, 28(12), 850-857.CrossRef

26.

Calabrese, S. K., Earnshaw, V. A., Krakower, D. S., et al. (2018). A closer look at racism and heterosexism in medical students’ clinical decision-making related to HIV pre-exposure prophylaxis (PrEP): Implications for PrEP education. AIDS and Behavior, 22(4), 1122–1138.CrossRefPubMedPubMedCentral

27.

Pathela, P., Jamison, K., Braunstein, S. L., Schillinger, J. A., Varma, J. K., & Blank, S. (2017). Incidence and predictors of HIV infection among men who have sex with men attending public sexually transmitted disease clinics, New York City, 2007–2012. AIDS and Behavior, 21(5), 1444–1451.CrossRefPubMed

28.

Marx, G. E., Bhatia, R., & Rietmeijer, C. A. (2016). An opportunity too good to miss: Implementing human immunodeficiency virus preexposure prophylaxis in sexually transmitted diseases clinics. Sexually Transmitted Diseases, 43(4), 266–267.CrossRefPubMed

29.

Hoover, K. W., Ham, D. C., Peters, P. J., Smith, D. K., & Bernstein, K. T. (2016). Human immunodeficiency virus prevention with preexposure prophylaxis in sexually transmitted disease clinics. Sexually Transmitted Diseases, 43(5), 277–282.CrossRefPubMed

30.

Leichliter, J. S., Heyer, K., Peterman, T. A., et al. (2017). US public STD clinical services in an era of declining public health funding, 2013–2014. Sexually Transmitted Diseases, 44(8), 505–509.CrossRefPubMedPubMedCentral

31.

National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. (2018). New CDC analysis shows steep and sustained increases in STDs in recent years. Retrieved Nov 28, 2018, from http://www.cdc.gov/nchstp/newsroom/2018/press-release-2018-std-prevention-conference.html.

32.

U. S. Office of Disease Prevention and Health Promotion. Healthy People 2020: Public Health Infrastructure. Retrieved Nov 29, 2018, from https://www.healthypeople.gov/2020/topics-objectives/topic/public-health-infrastructure.

33.

Liu, A. Y., Cohen, S. E., Vittinghoff, E., et al. (2016). HIV pre-exposure prophylaxis integrated with municipal and community based sexual health services. JAMA Internal Medicine, 176(1), 75–84.CrossRefPubMedPubMedCentral

34.

Parisi, D., Warren, B., Leung, S. Y., Akkaya-Hocagil, T., Qin, Q., Hahn, I., & Stevens, L. (2018). A multicomponent approach to evaluating a pre-exposure prophylaxis (PrEP) implementation program in five agencies in New York. Journal of the Association of Nurses in AIDS Care, 29(1), 10–19.CrossRefPubMed

35.

New York State Department of Health. PrEP Assistance Program (PrEP-AP). Retrieved Dec 4, 2018, from https://www.health.ny.gov/diseases/aids/general/prep/prep-ap_provider.htm.

36.

Patel, R. R., Mena, L., Nunn, A., et al. (2017). Impact of insurance coverage on utilization of pre-exposure prophylaxis for HIV prevention. PLoS ONE, 12(5), e0178737.CrossRefPubMedPubMedCentral

37.

Morgan, E., Ryan, D. T., Newcomb, M. E., & Mustanski, B. (2018). High rate of discontinuation may diminish prep coverage among young men who have sex with men. AIDS and Behavior, 22(11), 3645–3648.CrossRefPubMed

38.

McKenney, J., Chen, A., Hoover, K. W., et al. (2017). Optimal costs of pre-exposure prophylaxis for men who have sex with men. PLoS ONE, 12(6), e0178170.CrossRefPubMedPubMedCentral

39.

United Nations General Assembly. (2016). Political declaration on HIV and AIDS: On the fast track to accelerating the fight against HIV and to ending the AIDS Epidemic by 2030. Retrieved Dec 6, 2018, from http://www.unaids.org/sites/default/files/media-asset/2016-political-declaration-HIV-AIDS_en.pdf.

Title: Pre-exposure Prophylaxis for HIV Infection: Preventing Disease or Promoting Sexual Health?
Authors: Ronald O. Valdiserri
David R. Holtgrave
Publication date: 01-06-2019
Publisher: Springer US
Keywords: Sexually Transmitted Infection
Sexually Transmitted Infection
Sexually Transmitted Infection
Human Immunodeficiency Virus
Sexually Transmitted Infection
Published in: Journal of Community Health / Issue 3/2019
Print ISSN: 0094-5145
Electronic ISSN: 1573-3610
DOI: https://doi.org/10.1007/s10900-018-00616-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Pre-exposure Prophylaxis for HIV Infection: Preventing Disease or Promoting Sexual Health?

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 3/2019

Community-Based Cervical Cancer Education: Changes in Knowledge and Beliefs Among Vietnamese American Women

Ann Goerdt, Donna Page, Herbert M. Cole, Peter E. Udo Umoh, Leonard Kahan, and Faustino Quintanilla: Deformity Masks and Their Role in African Cultures: The Ann Goerdt Collection

Food Insecurity, Food Deserts, and Waist-to-Height Ratio: Variation by Sex and Race/Ethnicity

Sex Differences in the Association Between School Experiences and Marijuana Use Among African American Adolescents

Disparities in HPV Screening and Prevention in Metropolitan and Nonmetropolitan Regions of Michigan

Barriers to Disease Monitoring and Liver Cancer Surveillance Among Patients with Chronic Hepatitis B in the United States