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Open Access 01-12-2020 | Septicemia | Viewpoint

Nutritional support in sepsis: when less may be more

Authors: Gustav van Niekerk, Charné Meaker, Anna-Mart Engelbrecht

Published in: Critical Care | Issue 1/2020

Abstract

Despite sound basis to suspect that aggressive and early administration of nutritional support may hold therapeutic benefits during sepsis, recommendations for nutritional support have been somewhat underwhelming. Current guidelines (ESPEN and ASPEN) recognise a lack of clear evidence demonstrating the beneficial effect of nutritional support during sepsis, raising the question: why, given the perceived low efficacy of nutritionals support, are there no high-quality clinical trials on the efficacy of permissive underfeeding in sepsis? Here, we review clinically relevant beneficial effects of permissive underfeeding, motivating the urgent need to investigate the clinical benefits of delaying nutritional support during sepsis.

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Title: Nutritional support in sepsis: when less may be more
Authors: Gustav van Niekerk
Charné Meaker
Anna-Mart Engelbrecht
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Septicemia
Septicemia
Published in: Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-020-2771-4

At a glance: The STEP trials

Springer Medicine

Nutritional support in sepsis: when less may be more

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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