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Critical Care
Published in: Critical Care 1/2020

01-12-2020 | SARS-CoV-2 | Research Letter

Eosinophilia in critically ill COVID-19 patients: a French monocenter retrospective study

Authors: Megan Fraissé, Elsa Logre, Hervé Mentec, Radj Cally, Gaëtan Plantefève, Damien Contou

Published in: Critical Care | Issue 1/2020

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Excerpt

As reported in bacterial sepsis [1], the early phase of SARS-CoV-2 infection seems to be accompanied by eosinopenia [2‐4]. Conversely, our team noticed that several of our critically ill COVID-19 patients developed unexpected and unexplained eosinophilia during their ICU stay. Indeed, as white blood cells count is performed almost daily, monitoring and studying eosinophil course is simple in the ICU setting. To our knowledge, no study has focused on eosinophilia in COVID-19 although eosinophil recovery seven days after initial eosinopenia seems to be associated with a better outcome [3]. …
Literature
1.
Abidi K, Khoudri I, Belayachi J, Madani N, Zekraoui A, Zeggwagh AA, et al. Eosinopenia is a reliable marker of sepsis on admission to medical intensive care units. Crit Care. 2008;12:R59.CrossRef
2.
Li Q, Ding X, Xia G, Chen H-G, Chen F, Geng Z, et al. Eosinopenia and elevated C-reactive protein facilitate triage of COVID-19 patients in fever clinic: a retrospective case-control study. EClinicalMedicine. 2020;23:100375.CrossRef
3.
Mateos Gonzalez M, Sierra Gonzalo E, Casado Lopez I, Arnalich Fernandez F, Beato Perez JL, Monge Monge D, et al. The prognostic value of eosinophil recovery in COVID-19: a multicentre, retrospective cohort study on patients hospitalised in Spanish hospitals. medRxiv. 2020;2020.08.18.20172874.
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Du Y, Tu L, Zhu P, Mu M, Wang R, Yang P, et al. Clinical features of 85 fatal cases of COVID-19 from Wuhan. A retrospective observational study. Am J Respir Crit Care Med. 2020;201:1372–9.CrossRef
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Buetti N, Wicky PH, Le Hingrat Q, Ruckly S, Mazzuchelli T, Loiodice A, et al. SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients. Crit Care. 2020;24:1–6.CrossRef
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Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ, et al. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020;395:1033–4.CrossRef
Metadata
Title
Eosinophilia in critically ill COVID-19 patients: a French monocenter retrospective study
Authors
Megan Fraissé
Elsa Logre
Hervé Mentec
Radj Cally
Gaëtan Plantefève
Damien Contou
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03361-z

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