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Journal of Nuclear Cardiology

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Open Access 01-12-2020 | Sarcoidosis | Original Article

Same day comparison of PET/CT and PET/MR in patients with cardiac sarcoidosis

Authors: G. Wisenberg, MD, J. D. Thiessen, PhD, W. Pavlovsky, MD, J. Butler, BSc, B. Wilk, MSc, F. S. Prato, PhD

Published in: Journal of Nuclear Cardiology | Issue 6/2020

Abstract

Background

Inflammatory cardiac disorders, in particular, sarcoidosis, play an important role in left ventricular dysfunction, conduction abnormalities, and arrhythmias. In this study, we compared the imaging characteristics and diagnostic information obtained when patients were imaged sequentially with PET/CT and then with hybrid PET/MRI on the same day following a single ¹⁸F-FDG injection.

Methods

Ten patients with known or suspected sarcoidosis underwent imaging in sequence of (a) ^99mTc-MIBI, (b) ¹⁸F-FDG with PET/CT, and (c) ¹⁸F-FDG with 3T PET/MRI. Images were compared quantitatively by determination of SUV_max and SUV on a voxel by voxel basis, and qualitatively by two experienced observers.

Results

When both platforms were compared quantitatively, similar data for the evaluation of enhanced ¹⁸F-FDG uptake were obtained. Qualitatively, there were (1) several instances of normal perfusion with delayed enhancement and/or focal ¹⁸F-FDG uptake, (2) comparable enhanced ¹⁸F-FDG uptake on PET/CT vs. PET/MRI, and (3) diversity in disease patterns with delayed enhancement only, increased ¹⁸F-FDG uptake only, or both.

Conclusion

In this limited patient study, PET/CT and PET/MR provided similar diagnostic data for ¹⁸F-FDG uptake, and the concurrent acquisition of MR images provided further insight into the disease process.

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Title: Same day comparison of PET/CT and PET/MR in patients with cardiac sarcoidosis
Authors: G. Wisenberg, MD
J. D. Thiessen, PhD
W. Pavlovsky, MD
J. Butler, BSc
B. Wilk, MSc
F. S. Prato, PhD
Publication date: 01-12-2020
Publisher: Springer International Publishing
Keywords: Sarcoidosis
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Computed Tomography
Computed Tomography
Sarcoidosis
Positron Emission Tomography
Published in: Journal of Nuclear Cardiology / Issue 6/2020
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-018-01578-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Same day comparison of PET/CT and PET/MR in patients with cardiac sarcoidosis

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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