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Journal of Neuro-Oncology

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01-12-2020 | Salivary Gland Cancer | Topic Review

Management of advanced adenoid cystic carcinoma infiltrating the skull base: a contemporary review

Authors: E. Guazzo, B. Panizza

Published in: Journal of Neuro-Oncology | Issue 3/2020

Abstract

Introduction

This article provides an overview of the natural history and management of adenoid cystic carcinoma infiltrating the skull base (SB ACC).

Methods

A comprehensive review of the available literature and discussion regarding the current management of SB ACC.

Results

This review describes the unique pathology, appropriate diagnostic work-up and contemporary management options in SB ACC. There is a specific focus on the role of surgical resection with post-operative radiotherapy, given the literature suggesting a superior locoregional control rate. The importance of surgical decision making and varying surgical approaches are detailed. In addition, the emerging role of biological agents is discussed.

Conclusion

The gold standard for SB ACC is surgical resection and post-operative radiation, given the superior locoregional control. In patients not amendable to surgery, palliative radiation should be considered. The role of biological agents is still evolving. The complexity of SB ACC management mandates experienced multi-speciality management.

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Title: Management of advanced adenoid cystic carcinoma infiltrating the skull base: a contemporary review
Authors: E. Guazzo
B. Panizza
Publication date: 01-12-2020
Publisher: Springer US
Keywords: Salivary Gland Cancer
Radiotherapy
Salivary Gland Cancer
Published in: Journal of Neuro-Oncology / Issue 3/2020
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-019-03366-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Management of advanced adenoid cystic carcinoma infiltrating the skull base: a contemporary review

Abstract

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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