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Current Infectious Disease Reports

11-04-2024 | Skin, Soft Tissue, Bone and Joint Infections (N Safdar and A Haleem, Section Editors)

Role of Povidone-Iodine in Reducing Surgical Site Infection

Authors: A. Haleem, C. L. Abad

Published in: Current Infectious Disease Reports

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Abstract

Purpose of Review

Surgical site infections (SSIs) are associated with significant morbidity and mortality. Given the role of endogenous carriage of Staphylococcus aureus, current patient decolonization strategies revolve around the application of topical antiseptic agents prior to and at the time of surgery.

Recent Findings

Intranasal single-application povidone-iodine (PVP-I) on the day of surgery is an emerging, attractive alternative to the established approach of a 5-day course of intranasal mupirocin for preoperative decolonization.

Summary

PVP-I appears more convenient and cost-effective for both patients and healthcare systems, and its role in reducing SSI is under investigation. However, most published literature consists of retrospective, single-center studies primarily done in orthopedic surgical populations. Based on current data, PVP-I appears to be as equally effective in SSI reduction as mupirocin, but larger and better-quality studies are needed to implement a change from currently established preoperative decontamination practices.
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Metadata
Title
Role of Povidone-Iodine in Reducing Surgical Site Infection
Authors
A. Haleem
C. L. Abad
Publication date
11-04-2024
Publisher
Springer US
Published in
Current Infectious Disease Reports
Print ISSN: 1523-3847
Electronic ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-024-00841-z
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

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